7 items (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (416 aa)
	IGF1	Insulin like growth factor 1. (187 aa)
	APAF1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1252 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (277 aa)

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	CASP3	ENSMLUP00000007636	ENSMLUP00000002223	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 3; Belongs to the peptidase C14A family.	0.992
APAF1	CASP9	ENSMLUP00000007636	ENSMLUP00000008827	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 9; Belongs to the peptidase C14A family.	0.999
CASP3	APAF1	ENSMLUP00000002223	ENSMLUP00000007636	Caspase 3; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.992
CASP3	CASP9	ENSMLUP00000002223	ENSMLUP00000008827	Caspase 3; Belongs to the peptidase C14A family.	Caspase 9; Belongs to the peptidase C14A family.	0.988
CASP3	IGF1	ENSMLUP00000002223	ENSMLUP00000010317	Caspase 3; Belongs to the peptidase C14A family.	Insulin like growth factor 1.	0.639
CASP9	APAF1	ENSMLUP00000008827	ENSMLUP00000007636	Caspase 9; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.999
CASP9	CASP3	ENSMLUP00000008827	ENSMLUP00000002223	Caspase 9; Belongs to the peptidase C14A family.	Caspase 3; Belongs to the peptidase C14A family.	0.988
CASP9	IGF1	ENSMLUP00000008827	ENSMLUP00000010317	Caspase 9; Belongs to the peptidase C14A family.	Insulin like growth factor 1.	0.448
IGF1	CASP3	ENSMLUP00000010317	ENSMLUP00000002223	Insulin like growth factor 1.	Caspase 3; Belongs to the peptidase C14A family.	0.639
IGF1	CASP9	ENSMLUP00000010317	ENSMLUP00000008827	Insulin like growth factor 1.	Caspase 9; Belongs to the peptidase C14A family.	0.448