STRINGSTRING
RNF6 RNF6 MYO9A MYO9A G6PC3 G6PC3 G1QG66_MYOLU G1QG66_MYOLU G1QER2_MYOLU G1QER2_MYOLU RAG2 RAG2 G1QEB1_MYOLU G1QEB1_MYOLU G6PC2 G6PC2 TSSK4 TSSK4 G1QCZ0_MYOLU G1QCZ0_MYOLU REM1 REM1 NRAS NRAS RASL11B RASL11B G1QBB3_MYOLU G1QBB3_MYOLU G1QB68_MYOLU G1QB68_MYOLU ENSMLUP00000020598 ENSMLUP00000020598 G1Q9X2_MYOLU G1Q9X2_MYOLU G1Q9J5_MYOLU G1Q9J5_MYOLU G1Q7H0_MYOLU G1Q7H0_MYOLU IRS1 IRS1 LOC102430724 LOC102430724 TNFSF10 TNFSF10 CCNG2 CCNG2 CNTD2 CNTD2 S1PR1 S1PR1 G1Q1H5_MYOLU G1Q1H5_MYOLU FOXG1 FOXG1 G1Q0Z1_MYOLU G1Q0Z1_MYOLU G1Q0W8_MYOLU G1Q0W8_MYOLU FOXO4 FOXO4 LOC102430620 LOC102430620 G1PZF4_MYOLU G1PZF4_MYOLU G1PZA5_MYOLU G1PZA5_MYOLU ERAS ERAS IL10 IL10 RAF1 RAF1 PRMT3 PRMT3 TGFBR2 TGFBR2 RASGEF1A RASGEF1A STAT3 STAT3 TSSK6 TSSK6 RASGEF1B RASGEF1B IGF1R IGF1R CCND2 CCND2 PRMT1 PRMT1 SGK1 SGK1 SGK2 SGK2 CHUK CHUK KRAS KRAS IL6 IL6 SOS1 SOS1 EGF EGF PIK3R1 PIK3R1 PRKAB1 PRKAB1 GRB2 GRB2 GABARAPL2 GABARAPL2 TGFBR1 TGFBR1 STK11 STK11 SGK3 SGK3 EP300 EP300 MAPK10 MAPK10 ARAF ARAF GRAP GRAP MAPK8 MAPK8 G1PQ28_MYOLU G1PQ28_MYOLU MYO9B MYO9B PRKAA2 PRKAA2 PRKAA1 PRKAA1 AKT3 AKT3 SMAD4 SMAD4 INSR INSR RRAD RRAD CCNB2 CCNB2 LDLRAD4 LDLRAD4 RNF111 RNF111 TGFB3 TGFB3 FBXO32 FBXO32 TGFB1 TGFB1 REM2 REM2 BCL6 BCL6 CCNB1 CCNB1 G1PK52_MYOLU G1PK52_MYOLU HOMER3 HOMER3 PLK1 PLK1 STK4 STK4 MAP2K1 MAP2K1 GADD45G GADD45G LOC102430370 LOC102430370 IGF1 IGF1 MAPK3 MAPK3 G1PHV0_MYOLU G1PHV0_MYOLU CCND1 CCND1 PRKAG1 PRKAG1 PMEPA1 PMEPA1 PCK1 PCK1 HOMER1 HOMER1 IRS4 IRS4 CDKN1A CDKN1A FBXO25 FBXO25 IKBKB IKBKB MDM2 MDM2 IL7R IL7R PCK2 PCK2 SUCO SUCO TMEM232 TMEM232 GADD45B GADD45B G1PDJ5_MYOLU G1PDJ5_MYOLU PLK2 PLK2 PIK3CA PIK3CA GEM GEM AGAP2 AGAP2 SETD7 SETD7 NLK NLK G1PBZ4_MYOLU G1PBZ4_MYOLU PRMT8 PRMT8 PIK3CD PIK3CD G1P9Y9_MYOLU G1P9Y9_MYOLU BRAF BRAF TSSK2 TSSK2 TSSK1B TSSK1B LOC102430514 LOC102430514 FASLG FASLG PIK3CB PIK3CB TGFB2 TGFB2 RAG1 RAG1 TSSK3 TSSK3 CDK3 CDK3 CREBBP CREBBP BNIP3 BNIP3 PLK3 PLK3 G1NVZ4_MYOLU G1NVZ4_MYOLU HOMER2 HOMER2 G1NW48_MYOLU G1NW48_MYOLU SNAPIN SNAPIN MAPK12 MAPK12 SMAD3 SMAD3 AKT2 AKT2 FOXO3 FOXO3 SLC35E3 SLC35E3 PTEN PTEN SKP2 SKP2 CAT CAT ATG12 ATG12 CDKN1B CDKN1B SOS2 SOS2 LOC102424820 LOC102424820 G1P0X3_MYOLU G1P0X3_MYOLU INS INS PIK3R2 PIK3R2 G6PC G6PC PRKAG3 PRKAG3 SIRT1 SIRT1 PRKAG2 PRKAG2 G1P2J3_MYOLU G1P2J3_MYOLU GRM1 GRM1 PDPK1 PDPK1 GABARAP GABARAP SLC2A4 SLC2A4 GADD45A GADD45A CDK2 CDK2 USP7 USP7 FOXJ2 FOXJ2 PLK4 PLK4 CSDE1 CSDE1 G1P5B5_MYOLU G1P5B5_MYOLU FOXJ3 FOXJ3 MAPK9 MAPK9 G1P5Y1_MYOLU G1P5Y1_MYOLU MAPK14 MAPK14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RNF6Ring finger protein 6. (677 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2626 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
G1QG66_MYOLUUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1083 aa)
G1QER2_MYOLUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (360 aa)
RAG2Recombination activating 2. (527 aa)
G1QEB1_MYOLUSH2 domain-containing protein. (266 aa)
G6PC2Glucose-6-phosphatase catalytic subunit 2. (358 aa)
TSSK4Testis specific serine kinase 4; Belongs to the protein kinase superfamily. (328 aa)
G1QCZ0_MYOLUTAZ-type domain-containing protein. (636 aa)
REM1RRAD and GEM like GTPase 1. (212 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
RASL11BRAS like family 11 member B. (182 aa)
G1QBB3_MYOLUSH2 domain-containing protein. (270 aa)
G1QB68_MYOLUProtein kinase domain-containing protein. (144 aa)
ENSMLUP00000020598annotation not available (291 aa)
G1Q9X2_MYOLUMethyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (307 aa)
G1Q9J5_MYOLUAMPK1_CBM domain-containing protein. (183 aa)
G1Q7H0_MYOLUUncharacterized protein. (544 aa)
IRS1Insulin receptor substrate 1. (1231 aa)
LOC102430724Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (368 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (344 aa)
CNTD2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (284 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
G1Q1H5_MYOLUUncharacterized protein. (450 aa)
FOXG1Uncharacterized protein. (188 aa)
G1Q0Z1_MYOLUUncharacterized protein. (738 aa)
G1Q0W8_MYOLUUncharacterized protein. (89 aa)
FOXO4Forkhead box O4. (506 aa)
LOC102430620Uncharacterized protein. (226 aa)
G1PZF4_MYOLUUncharacterized protein. (708 aa)
G1PZA5_MYOLUDUF3452 domain-containing protein. (183 aa)
ERASES cell expressed Ras. (229 aa)
IL10Interleukin 10. (178 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
PRMT3Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (531 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
RASGEF1ARasGEF domain family member 1A. (480 aa)
STAT3Signal transducer and activator of transcription. (773 aa)
TSSK6Testis specific serine kinase 6; Belongs to the protein kinase superfamily. (273 aa)
RASGEF1BRasGEF domain family member 1B. (475 aa)
IGF1RTyrosine-protein kinase receptor. (1155 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (291 aa)
PRMT1Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (361 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (379 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (746 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
IL6Interleukin 6. (208 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1178 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (471 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (441 aa)
SGK3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa)
EP300E1A binding protein p300. (2412 aa)
MAPK10Mitogen-activated protein kinase. (422 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (613 aa)
GRAPUncharacterized protein. (217 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
G1PQ28_MYOLUAMPKBI domain-containing protein. (221 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2127 aa)
PRKAA2Non-specific serine/threonine protein kinase. (528 aa)
PRKAA1Non-specific serine/threonine protein kinase. (517 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa)
SMAD4Mothers against decapentaplegic homolog. (554 aa)
INSRTyrosine-protein kinase receptor. (1336 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (397 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (290 aa)
RNF111Ring finger protein 111. (994 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (449 aa)
FBXO32F-box protein 32. (355 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
REM2RRAD and GEM like GTPase 2. (263 aa)
BCL6BCL6 transcription repressor. (708 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (433 aa)
G1PK52_MYOLUSuperoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
HOMER3WH1 domain-containing protein. (360 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
STK4Serine/threonine kinase 4. (511 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
GADD45GGrowth arrest and DNA damage inducible gamma. (159 aa)
LOC102430370Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
IGF1Insulin like growth factor 1. (187 aa)
MAPK3Mitogen-activated protein kinase. (370 aa)
G1PHV0_MYOLUFAT domain-containing protein. (2192 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (329 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (253 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (624 aa)
HOMER1Homer scaffold protein 1. (364 aa)
IRS4Insulin receptor substrate 4. (1031 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (192 aa)
FBXO25F-box protein 25. (372 aa)
IKBKBUncharacterized protein. (756 aa)
MDM2MDM2 proto-oncogene. (499 aa)
IL7RInterleukin 7 receptor. (457 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (662 aa)
SUCOSUN domain containing ossification factor. (1257 aa)
TMEM232Transmembrane protein 232. (548 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (160 aa)
G1PDJ5_MYOLUBclx_interact domain-containing protein. (70 aa)
PLK2Serine/threonine-protein kinase PLK. (675 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1070 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (293 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1030 aa)
SETD7SET domain containing 7, histone lysine methyltransferase. (365 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
G1PBZ4_MYOLUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (373 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (370 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1053 aa)
G1P9Y9_MYOLUFork-head domain-containing protein. (483 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (792 aa)
TSSK2Testis specific serine kinase 2; Belongs to the protein kinase superfamily. (372 aa)
TSSK1BProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (369 aa)
LOC102430514Uncharacterized protein. (87 aa)
FASLGTumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
TSSK3Testis specific serine kinase 3. (268 aa)
CDK3Cyclin dependent kinase 3. (241 aa)
CREBBPCREB binding protein. (2408 aa)
BNIP3BCL2 interacting protein 3. (204 aa)
PLK3Protein kinase domain-containing protein. (323 aa)
G1NVZ4_MYOLUUncharacterized protein. (433 aa)
HOMER2Homer scaffold protein 2. (278 aa)
G1NW48_MYOLUCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (357 aa)
SNAPINSNAP associated protein. (138 aa)
MAPK12Mitogen-activated protein kinase. (323 aa)
SMAD3Mothers against decapentaplegic homolog. (395 aa)
AKT2Non-specific serine/threonine protein kinase. (467 aa)
FOXO3Forkhead box O3. (672 aa)
SLC35E3Solute carrier family 35 member E3. (313 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (352 aa)
SKP2S-phase kinase associated protein 2. (427 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (161 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1304 aa)
LOC102424820Uncharacterized protein. (473 aa)
G1P0X3_MYOLUSerine/threonine-protein kinase PLK. (587 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
PIK3R2Uncharacterized protein. (730 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (496 aa)
SIRT1Sirtuin 1. (610 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (320 aa)
G1P2J3_MYOLUUncharacterized protein. (747 aa)
GRM1Glutamate metabotropic receptor 1. (1205 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (557 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1101 aa)
FOXJ2Forkhead box J2. (560 aa)
PLK4Polo like kinase 4. (963 aa)
CSDE1Cold shock domain containing E1. (813 aa)
G1P5B5_MYOLUUncharacterized protein. (635 aa)
FOXJ3Forkhead box J3. (623 aa)
MAPK9Mitogen-activated protein kinase. (423 aa)
G1P5Y1_MYOLUMitogen-activated protein kinase. (321 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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