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| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa) |
| | FASLG | Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa) |
| | BAD | BCL2 associated agonist of cell death. (174 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1421 aa) |
| | PMAIP1 | Uncharacterized protein. (54 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | SPTAN1 | Spectrin alpha, non-erythrocytic 1. (2511 aa) |
| | DAXX | Death domain associated protein. (761 aa) |
| | G1PA19_MYOLU | Uncharacterized protein. (1508 aa) |
| | PARP3 | Poly [ADP-ribose] polymerase. (446 aa) |
| | CAPN13 | Calpain 13; Belongs to the peptidase C2 family. (668 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1053 aa) |
| | TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | LOC102441463 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (261 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1252 aa) |
| | G1PBK4_MYOLU | Uncharacterized protein. (427 aa) |
| | G1PBZ4_MYOLU | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (373 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (545 aa) |
| | GEM | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (293 aa) |
| | PRF1 | Perforin 1. (555 aa) |
| | G1PCN7_MYOLU | Uncharacterized protein. (613 aa) |
| | PIK3CA | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | G1PDJ5_MYOLU | Bclx_interact domain-containing protein. (70 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | SUCO | SUN domain containing ossification factor. (1257 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (416 aa) |
| | LMNB1 | Lamin B1; Belongs to the intermediate filament family. (586 aa) |
| | IKBKB | Uncharacterized protein. (756 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (193 aa) |
| | G1PG23_MYOLU | Receptor protein-tyrosine kinase. (716 aa) |
| | CTSC | Cathepsin C; Belongs to the peptidase C1 family. (359 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1015 aa) |
| | TUBA1A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa) |
| | CTSW | Cathepsin W; Belongs to the peptidase C1 family. (371 aa) |
| | TRADD | TNFRSF1A associated via death domain. (310 aa) |
| | HTRA4 | HtrA serine peptidase 4. (481 aa) |
| | G1PHV0_MYOLU | FAT domain-containing protein. (2192 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (370 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2648 aa) |
| | LOC102425233 | Uncharacterized protein. (335 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2048 aa) |
| | G1PJJ0_MYOLU | Ion_trans domain-containing protein. (561 aa) |
| | ERN2 | Endoplasmic reticulum to nucleus signaling 2. (796 aa) |
| | DAB2IP | DAB2 interacting protein. (1089 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase. (903 aa) |
| | CTSO | Cathepsin O; Belongs to the peptidase C1 family. (321 aa) |
| | CTSV | Uncharacterized protein; Belongs to the peptidase C1 family. (335 aa) |
| | LMNB2 | Lamin B2; Belongs to the intermediate filament family. (607 aa) |
| | G1PMR9_MYOLU | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (253 aa) |
| | RRAD | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa) |
| | LOC102430512 | Uncharacterized protein; Belongs to the peptidase C2 family. (565 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (448 aa) |
| | SCNN1A | Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (658 aa) |
| | ENDOG | Endonuclease. (294 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (422 aa) |
| | LOC102438614 | Uncharacterized protein. (127 aa) |
| | CTSZ | Cathepsin Z; Belongs to the peptidase C1 family. (270 aa) |
| | TUBA3D | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | CASP2 | Caspase 2; Belongs to the peptidase C14A family. (452 aa) |
| | PARP2 | Poly [ADP-ribose] polymerase. (458 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | LOC102431314 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa) |
| | FAS | Fas cell surface death receptor. (338 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (481 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (603 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (621 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2418 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (668 aa) |
| | HTRA2 | HtrA serine peptidase 2. (456 aa) |
| | HPS5 | Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (1129 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (746 aa) |
| | C7orf31 | Chromosome 7 open reading frame 31. (590 aa) |
| | CENPU | Centromere protein U. (372 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (974 aa) |
| | CAPN2 | Calpain 2; Belongs to the peptidase C2 family. (698 aa) |
| | DIABLO | Uncharacterized protein. (238 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | ERAS | ES cell expressed Ras. (229 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (191 aa) |
| | G1PZ39_MYOLU | Uncharacterized protein. (264 aa) |
| | G1PZ51_MYOLU | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa) |
| | LOC102440001 | Uncharacterized protein; Belongs to the peptidase C1 family. (324 aa) |
| | LOC102430620 | Uncharacterized protein. (226 aa) |
| | LOC102438700 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa) |
| | G1Q0J5_MYOLU | Uncharacterized protein. (145 aa) |
| | CAPN3 | Calpain 3; Belongs to the peptidase C2 family. (715 aa) |
| | ACTL8 | Actin like 8; Belongs to the actin family. (367 aa) |
| | ENSMLUP00000017338 | annotation not available (451 aa) |
| | G1Q0X3_MYOLU | Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (426 aa) |
| | G1Q169_MYOLU | Uncharacterized protein. (139 aa) |
| | G1Q1A7_MYOLU | Uncharacterized protein. (329 aa) |
| | LOC102427260 | Uncharacterized protein. (143 aa) |
| | G1Q1E5_MYOLU | Uncharacterized protein; Belongs to the peptidase C14A family. (525 aa) |
| | SEPTIN4 | Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (586 aa) |
| | G1Q234_MYOLU | BZIP domain-containing protein; Belongs to the bZIP family. (204 aa) |
| | G1Q2L0_MYOLU | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (245 aa) |
| | DFFB | DFF40 domain-containing protein. (189 aa) |
| | LOC102424990 | Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | G1Q487_MYOLU | Uncharacterized protein. (48 aa) |
| | G1Q4Q8_MYOLU | CathepsinC_exc domain-containing protein. (142 aa) |
| | LOC102420929 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa) |
| | G1Q5B6_MYOLU | Uncharacterized protein; Belongs to the peptidase C1 family. (326 aa) |
| | LOC102419640 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC102432058 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | G1Q5X6_MYOLU | Uncharacterized protein. (145 aa) |
| | LOC102420454 | MIR domain-containing protein. (102 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (281 aa) |
| | LOC102422616 | Uncharacterized protein; Belongs to the peptidase C14A family. (371 aa) |
| | LOC102438304 | Uncharacterized protein. (140 aa) |
| | G1Q8P3_MYOLU | Uncharacterized protein. (143 aa) |
| | G1Q8T5_MYOLU | Uncharacterized protein. (80 aa) |
| | CAPN14 | Calpain 14; Belongs to the peptidase C2 family. (769 aa) |
| | G1Q9T3_MYOLU | Uncharacterized protein. (72 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (425 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | TUBA1B | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa) |
| | EXOG | Exo/endonuclease G. (368 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | ACTBL2 | Actin beta like 2. (370 aa) |
| | CTSS | Cathepsin S; Belongs to the peptidase C1 family. (342 aa) |
| | CTSK | Cathepsin K; Belongs to the peptidase C1 family. (331 aa) |
| | LOC102433374 | Uncharacterized protein. (374 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | PARP4 | Poly [ADP-ribose] polymerase. (1711 aa) |
| | CASP7 | Caspase 7; Belongs to the peptidase C14A family. (269 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (238 aa) |
| | PIK3R2 | Uncharacterized protein. (730 aa) |
| | LOC102426649 | Uncharacterized protein; Belongs to the peptidase C1 family. (344 aa) |
| | CAPN12 | Calpain 12; Belongs to the peptidase C2 family. (658 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (316 aa) |
| | NFKBIA | ANK_REP_REGION domain-containing protein. (238 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (557 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | TRAF1 | TNF receptor-associated factor. (415 aa) |
| | CAPN11 | Calpain 11; Belongs to the peptidase C2 family. (734 aa) |
| | CTSB | Cathepsin B; Belongs to the peptidase C1 family. (298 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (957 aa) |
| | CSDE1 | Cold shock domain containing E1. (813 aa) |
| | CFLAR | CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (487 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (423 aa) |
| | G1P5Y1_MYOLU | Mitogen-activated protein kinase. (321 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (972 aa) |
| | BIRC5 | Baculoviral IAP repeat containing 5. (142 aa) |
| | G1QG66_MYOLU | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1083 aa) |
| | G1QF53_MYOLU | Uncharacterized protein. (91 aa) |
| | LOC102430141 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | ATF4 | BZIP domain-containing protein. (347 aa) |
| | G1QER2_MYOLU | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (360 aa) |
| | G1QEB1_MYOLU | SH2 domain-containing protein. (266 aa) |
| | NGF | Nerve growth factor; Belongs to the NGF-beta family. (241 aa) |
| | G1QDF7_MYOLU | Tubulin domain-containing protein. (196 aa) |
| | G1QCQ8_MYOLU | Uncharacterized protein. (333 aa) |
| | REM1 | RRAD and GEM like GTPase 1. (212 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | LMNA | Lamin A/C; Belongs to the intermediate filament family. (665 aa) |
| | G1QBN4_MYOLU | Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (208 aa) |
| | G1QBH9_MYOLU | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (406 aa) |
| | G1QBB3_MYOLU | SH2 domain-containing protein. (270 aa) |
| | G1QAV8_MYOLU | Uncharacterized protein. (324 aa) |
| | ENSMLUP00000020832 | annotation not available (105 aa) |
| | G1QAH7_MYOLU | Uncharacterized protein; Belongs to the peptidase C14A family. (522 aa) |
| | LOC102421025 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | G1QA95_MYOLU | Uncharacterized protein; Belongs to the peptidase C1 family. (330 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | DFFA | DNA fragmentation factor subunit alpha. (331 aa) |
| | G1NTF8_MYOLU | Uncharacterized protein; Belongs to the peptidase C14A family. (413 aa) |
| | CTSF | Cathepsin F; Belongs to the peptidase C1 family. (460 aa) |
| | CASP6 | Caspase 6; Belongs to the peptidase C14A family. (278 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | G1NVZ4_MYOLU | Uncharacterized protein. (433 aa) |
| | XIAP | X-linked inhibitor of apoptosis. (497 aa) |
| | PTPN13 | Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2483 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (467 aa) |
| | L7N1A9_MYOLU | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (128 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
