STRINGSTRING
CSDE1 CSDE1 G1QEZ1_MYOLU G1QEZ1_MYOLU ATF4 ATF4 G1QEB1_MYOLU G1QEB1_MYOLU LOC102439967 LOC102439967 G1QD05_MYOLU G1QD05_MYOLU G1QCQ8_MYOLU G1QCQ8_MYOLU NRAS NRAS ENSMLUP00000021192 ENSMLUP00000021192 G1QBB3_MYOLU G1QBB3_MYOLU G1QA52_MYOLU G1QA52_MYOLU G1Q9J5_MYOLU G1Q9J5_MYOLU G1Q8T5_MYOLU G1Q8T5_MYOLU LOC102437790 LOC102437790 ADCY7 ADCY7 G1Q7Q1_MYOLU G1Q7Q1_MYOLU IRS1 IRS1 G1Q657_MYOLU G1Q657_MYOLU ATF6B ATF6B G1Q3H7_MYOLU G1Q3H7_MYOLU G1Q2X6_MYOLU G1Q2X6_MYOLU G1PZ51_MYOLU G1PZ51_MYOLU CREB3L2 CREB3L2 ERAS ERAS PPARG PPARG ATG13 ATG13 IGF1R IGF1R AKT1S1 AKT1S1 CAMKK2 CAMKK2 PPARGC1A PPARGC1A CREB1 CREB1 ADIPOR1 ADIPOR1 KRAS KRAS ATF2 ATF2 PIK3R1 PIK3R1 PRKAB1 PRKAB1 STK11 STK11 ADCY4 ADCY4 SESN3 SESN3 G1PQ28_MYOLU G1PQ28_MYOLU PRKAA2 PRKAA2 PRKAA1 PRKAA1 AKT3 AKT3 ADCY3 ADCY3 PTRHD1 PTRHD1 ATG5 ATG5 INSR INSR CREB5 CREB5 ADCY2 ADCY2 KL KL CREB3L4 CREB3L4 G1PK52_MYOLU G1PK52_MYOLU ADCY8 ADCY8 EHMT1 EHMT1 CREB3 CREB3 IGF1 IGF1 EIF4E2 EIF4E2 PRKAG1 PRKAG1 ADCY6 ADCY6 IRS4 IRS4 G1PG02_MYOLU G1PG02_MYOLU BAX BAX CREB3L1 CREB3L1 PIK3CA PIK3CA RPTOR RPTOR ATG101 ATG101 RELA RELA CREB3L3 CREB3L3 RHEBL1 RHEBL1 PRKACA PRKACA ADCY5 ADCY5 PIK3CD PIK3CD G1P9Y9_MYOLU G1P9Y9_MYOLU EIF4EBP1 EIF4EBP1 CAMK4 CAMK4 SESN1 SESN1 TSC1 TSC1 TP53 TP53 NFKB1 NFKB1 ADCY9 ADCY9 RPS6KB2 RPS6KB2 EIF4E EIF4E G1P265_MYOLU G1P265_MYOLU PRKAG2 PRKAG2 RHEB RHEB SIRT1 SIRT1 TSC2 TSC2 PRKAG3 PRKAG3 PIK3R2 PIK3R2 INS INS RPS6KB1 RPS6KB1 PRKACB PRKACB CAT CAT FOXO3 FOXO3 AKT2 AKT2 ADIPOR2 ADIPOR2 G1NVZ4_MYOLU G1NVZ4_MYOLU EIF4E1B EIF4E1B G1NUS6_MYOLU G1NUS6_MYOLU APPL1 APPL1 ADIPOQ ADIPOQ SESN2 SESN2 PIK3CB PIK3CB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSDE1Cold shock domain containing E1. (813 aa)
G1QEZ1_MYOLUProtein kinase C. (646 aa)
ATF4BZIP domain-containing protein. (347 aa)
G1QEB1_MYOLUSH2 domain-containing protein. (266 aa)
LOC102439967Uncharacterized protein. (562 aa)
G1QD05_MYOLUUncharacterized protein. (389 aa)
G1QCQ8_MYOLUUncharacterized protein. (333 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
ENSMLUP00000021192annotation not available (245 aa)
G1QBB3_MYOLUSH2 domain-containing protein. (270 aa)
G1QA52_MYOLUUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (216 aa)
G1Q9J5_MYOLUAMPK1_CBM domain-containing protein. (183 aa)
G1Q8T5_MYOLUUncharacterized protein. (80 aa)
LOC102437790Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (848 aa)
ADCY7Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (574 aa)
G1Q7Q1_MYOLUNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (443 aa)
IRS1Insulin receptor substrate 1. (1231 aa)
G1Q657_MYOLUUncharacterized protein. (50 aa)
ATF6BActivating transcription factor 6 beta. (653 aa)
G1Q3H7_MYOLUUncharacterized protein. (386 aa)
G1Q2X6_MYOLUUncharacterized protein. (386 aa)
G1PZ51_MYOLUCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (526 aa)
ERASES cell expressed Ras. (229 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (551 aa)
IGF1RTyrosine-protein kinase receptor. (1155 aa)
AKT1S1AKT1 substrate 1. (253 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (578 aa)
PPARGC1APPARG coactivator 1 alpha. (796 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
ADIPOR1Uncharacterized protein. (375 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (441 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
SESN3Sestrin 3. (470 aa)
G1PQ28_MYOLUAMPKBI domain-containing protein. (221 aa)
PRKAA2Non-specific serine/threonine protein kinase. (528 aa)
PRKAA1Non-specific serine/threonine protein kinase. (517 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1151 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (277 aa)
INSRTyrosine-protein kinase receptor. (1336 aa)
CREB5cAMP responsive element binding protein 5. (276 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (852 aa)
KLKlotho. (1008 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (394 aa)
G1PK52_MYOLUSuperoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
EHMT1Euchromatic histone lysine methyltransferase 1. (1273 aa)
CREB3cAMP responsive element binding protein 3. (365 aa)
IGF1Insulin like growth factor 1. (187 aa)
EIF4E2Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (245 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (329 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1165 aa)
IRS4Insulin receptor substrate 4. (1031 aa)
G1PG02_MYOLUATG11 domain-containing protein. (1031 aa)
BAXBCL2 associated X, apoptosis regulator. (193 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (486 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1070 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1012 aa)
ATG101Autophagy related 101. (218 aa)
RELARELA proto-oncogene, NF-kB subunit. (545 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (473 aa)
RHEBL1RHEB like 1. (183 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (243 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1215 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1053 aa)
G1P9Y9_MYOLUFork-head domain-containing protein. (483 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (423 aa)
SESN1Sestrin 1. (492 aa)
TSC1TSC complex subunit 1. (1167 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa)
NFKB1Nuclear factor kappa B subunit 1. (972 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa)
EIF4EUncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (218 aa)
G1P265_MYOLUSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2547 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (320 aa)
RHEBRas homolog, mTORC1 binding. (179 aa)
SIRT1Sirtuin 1. (610 aa)
TSC2TSC complex subunit 2. (1809 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (496 aa)
PIK3R2Uncharacterized protein. (730 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
FOXO3Forkhead box O3. (672 aa)
AKT2Non-specific serine/threonine protein kinase. (467 aa)
ADIPOR2Uncharacterized protein. (386 aa)
G1NVZ4_MYOLUUncharacterized protein. (433 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (247 aa)
G1NUS6_MYOLUTubulin-specific chaperone A; Belongs to the TBCA family. (106 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
SESN2Sestrin 2. (489 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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