STRINGSTRING
ADCY7 ADCY7 G1Q7Q1_MYOLU G1Q7Q1_MYOLU IRS1 IRS1 G1Q6V0_MYOLU G1Q6V0_MYOLU HSPA1L HSPA1L G1Q320_MYOLU G1Q320_MYOLU G1Q2N3_MYOLU G1Q2N3_MYOLU FOXA2 FOXA2 PIK3CB PIK3CB G1NVZ4_MYOLU G1NVZ4_MYOLU AKT2 AKT2 FOXO3 FOXO3 CAT CAT G1NZE8_MYOLU G1NZE8_MYOLU PRKACB PRKACB RPS6KB1 RPS6KB1 INS INS PIK3R2 PIK3R2 PRKAG3 PRKAG3 SIRT1 SIRT1 PRKAG2 PRKAG2 G1P265_MYOLU G1P265_MYOLU TIMM8A TIMM8A HSPA8 HSPA8 LOC102425512 LOC102425512 CLPB CLPB RPS6KB2 RPS6KB2 CSDE1 CSDE1 ADCY9 ADCY9 G1P9Y9_MYOLU G1P9Y9_MYOLU PIK3CD PIK3CD ADCY5 ADCY5 PRKACA PRKACA RPTOR RPTOR PIK3CA PIK3CA IRS4 IRS4 ADCY6 ADCY6 PRKAG1 PRKAG1 IGF1 IGF1 SOD1 SOD1 ADCY8 ADCY8 TIMM8B TIMM8B G1PK52_MYOLU G1PK52_MYOLU ADCY2 ADCY2 INSR INSR HDAC1 HDAC1 ATG5 ATG5 PTRHD1 PTRHD1 ADCY3 ADCY3 AKT3 AKT3 PRKAA1 PRKAA1 PRKAA2 PRKAA2 G1PQ28_MYOLU G1PQ28_MYOLU ADCY4 ADCY4 KCNK1 KCNK1 EIF4EBP2 EIF4EBP2 PRKAB1 PRKAB1 SOD3 SOD3 LOC102425210 LOC102425210 PIK3R1 PIK3R1 KRAS KRAS AKT1S1 AKT1S1 IGF1R IGF1R G1PY32_MYOLU G1PY32_MYOLU ERAS ERAS G1PYS3_MYOLU G1PYS3_MYOLU G1QEZ1_MYOLU G1QEZ1_MYOLU G1QEB1_MYOLU G1QEB1_MYOLU NRAS NRAS G1QBB3_MYOLU G1QBB3_MYOLU FOXA1 FOXA1 G1Q9J5_MYOLU G1Q9J5_MYOLU G1Q987_MYOLU G1Q987_MYOLU LOC102437790 LOC102437790
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY7Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (574 aa)
G1Q7Q1_MYOLUNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (443 aa)
IRS1Insulin receptor substrate 1. (1231 aa)
G1Q6V0_MYOLUHistone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
G1Q320_MYOLUzf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (95 aa)
G1Q2N3_MYOLUUncharacterized protein. (318 aa)
FOXA2Forkhead box A2. (380 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
G1NVZ4_MYOLUUncharacterized protein. (433 aa)
AKT2Non-specific serine/threonine protein kinase. (467 aa)
FOXO3Forkhead box O3. (672 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
G1NZE8_MYOLUHistone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (512 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
PIK3R2Uncharacterized protein. (730 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (496 aa)
SIRT1Sirtuin 1. (610 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (320 aa)
G1P265_MYOLUSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2547 aa)
TIMM8ATranslocase of inner mitochondrial membrane 8A; Belongs to the small Tim family. (97 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
LOC102425512Uncharacterized protein; Belongs to the heat shock protein 70 family. (681 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (707 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa)
CSDE1Cold shock domain containing E1. (813 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
G1P9Y9_MYOLUFork-head domain-containing protein. (483 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1053 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1215 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (243 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1012 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1070 aa)
IRS4Insulin receptor substrate 4. (1031 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1165 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (329 aa)
IGF1Insulin like growth factor 1. (187 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (75 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
TIMM8BTranslocase of inner mitochondrial membrane 8 homolog B; Belongs to the small Tim family. (83 aa)
G1PK52_MYOLUSuperoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (852 aa)
INSRTyrosine-protein kinase receptor. (1336 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (277 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1151 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa)
PRKAA1Non-specific serine/threonine protein kinase. (517 aa)
PRKAA2Non-specific serine/threonine protein kinase. (528 aa)
G1PQ28_MYOLUAMPKBI domain-containing protein. (221 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
KCNK1Potassium two pore domain channel subfamily K member 1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (243 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (72 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (239 aa)
LOC102425210Uncharacterized protein; Belongs to the heat shock protein 70 family. (716 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
AKT1S1AKT1 substrate 1. (253 aa)
IGF1RTyrosine-protein kinase receptor. (1155 aa)
G1PY32_MYOLUUncharacterized protein; Belongs to the heat shock protein 70 family. (516 aa)
ERASES cell expressed Ras. (229 aa)
G1PYS3_MYOLUHistone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
G1QEZ1_MYOLUProtein kinase C. (646 aa)
G1QEB1_MYOLUSH2 domain-containing protein. (266 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
G1QBB3_MYOLUSH2 domain-containing protein. (270 aa)
FOXA1Forkhead box A1. (464 aa)
G1Q9J5_MYOLUAMPK1_CBM domain-containing protein. (183 aa)
G1Q987_MYOLUUncharacterized protein. (387 aa)
LOC102437790Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (848 aa)
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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