37 items (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PMAIP1	Uncharacterized protein. (54 aa)
	BCL2L1	BCL2 like 1. (233 aa)
	APAF1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1252 aa)
	G1PDJ5_MYOLU	Bclx_interact domain-containing protein. (70 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (416 aa)
	BAX	BCL2 associated X, apoptosis regulator. (193 aa)
	TNFRSF1A	TNF receptor superfamily member 1A. (448 aa)
	SCNN1A	Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (658 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	MAPK10	Mitogen-activated protein kinase. (422 aa)
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (481 aa)
	BIRC3	Baculoviral IAP repeat containing 3. (603 aa)
	BIRC2	Baculoviral IAP repeat containing 2. (621 aa)
	HTRA2	HtrA serine peptidase 2. (456 aa)
	C7orf31	Chromosome 7 open reading frame 31. (590 aa)
	BIRC6	Baculoviral IAP repeat containing 6. (4865 aa)
	DIABLO	Uncharacterized protein. (238 aa)
	BID	BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (191 aa)
	G1PZN5_MYOLU	Uncharacterized protein. (427 aa)
	LOC102427260	Uncharacterized protein. (143 aa)
	SEPTIN4	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (586 aa)
	NGFR	Nerve growth factor receptor. (432 aa)
	LOC102422056	Uncharacterized protein. (445 aa)
	LOC102417876	Uncharacterized protein. (445 aa)
	LOC102420929	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa)
	LOC102419640	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	LOC102421025	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	ENSMLUP00000020832	annotation not available (105 aa)
	LOC102443111	DUF4203 domain-containing protein. (355 aa)
	TMEM198	Transmembrane protein 198. (360 aa)
	BOK	BCL2 family apoptosis regulator BOK. (162 aa)
	XIAP	X-linked inhibitor of apoptosis. (497 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (277 aa)
	CASP7	Caspase 7; Belongs to the peptidase C14A family. (269 aa)
	BECN1	Beclin 1. (448 aa)
	MAPK9	Mitogen-activated protein kinase. (423 aa)
	BIRC5	Baculoviral IAP repeat containing 5. (142 aa)

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	BAX	ENSMLUP00000007636	ENSMLUP00000009353	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BCL2 associated X, apoptosis regulator.	0.792
APAF1	BCL2L1	ENSMLUP00000007636	ENSMLUP00000006829	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BCL2 like 1.	0.854
APAF1	BID	ENSMLUP00000007636	ENSMLUP00000016550	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.	0.572
APAF1	BIRC2	ENSMLUP00000007636	ENSMLUP00000014380	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat containing 2.	0.848
APAF1	BIRC3	ENSMLUP00000007636	ENSMLUP00000014372	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat containing 3.	0.848
APAF1	BIRC5	ENSMLUP00000007636	ENSMLUP00000005735	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat containing 5.	0.838
APAF1	BIRC6	ENSMLUP00000007636	ENSMLUP00000015232	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat containing 6.	0.964
APAF1	BOK	ENSMLUP00000007636	ENSMLUP00000022590	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BCL2 family apoptosis regulator BOK.	0.755
APAF1	CASP3	ENSMLUP00000007636	ENSMLUP00000002223	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 3; Belongs to the peptidase C14A family.	0.992
APAF1	CASP7	ENSMLUP00000007636	ENSMLUP00000003478	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 7; Belongs to the peptidase C14A family.	0.963
APAF1	CASP8	ENSMLUP00000007636	ENSMLUP00000014156	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 8; Belongs to the peptidase C14A family.	0.973
APAF1	CASP9	ENSMLUP00000007636	ENSMLUP00000008827	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 9; Belongs to the peptidase C14A family.	0.999
APAF1	DIABLO	ENSMLUP00000007636	ENSMLUP00000015724	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.848
APAF1	ENSMLUP00000020832	ENSMLUP00000007636	ENSMLUP00000020832	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	annotation not available	0.996
APAF1	G1PDJ5_MYOLU	ENSMLUP00000007636	ENSMLUP00000008546	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Bclx_interact domain-containing protein.	0.505
APAF1	HTRA2	ENSMLUP00000007636	ENSMLUP00000014816	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	HtrA serine peptidase 2.	0.573
APAF1	LOC102419640	ENSMLUP00000007636	ENSMLUP00000018972	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.996
APAF1	LOC102420929	ENSMLUP00000007636	ENSMLUP00000018852	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.996
APAF1	LOC102421025	ENSMLUP00000007636	ENSMLUP00000020649	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.996
APAF1	LOC102427260	ENSMLUP00000007636	ENSMLUP00000017525	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.838