72 items (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	HTR1B	5-hydroxytryptamine receptor 1B. (383 aa)
	TAS1R2	Taste 1 receptor member 2. (775 aa)
	GABRA4	Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (554 aa)
	SCNN1G	Sodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (650 aa)
	GNB3	G protein subunit beta 3. (340 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1198 aa)
	P2RX3	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
	TAS2R3	Taste receptor type 2. (316 aa)
	KCNK5	Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (521 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (243 aa)
	HTR3B	5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (442 aa)
	HTR3A	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (486 aa)
	SCN9A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1984 aa)
	PDE1A	Phosphodiesterase. (511 aa)
	CACNA1A	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2210 aa)
	HTR1F	5-hydroxytryptamine receptor 1F. (366 aa)
	LOC102421327	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
	LOC102420721	5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (458 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1165 aa)
	LOC102442662	G_PROTEIN_RECEP_F3_4 domain-containing protein. (415 aa)
	GABRA2	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (391 aa)
	LOC102432706	Phosphoinositide phospholipase C. (954 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2048 aa)
	SCNN1B	Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (539 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
	GABRA3	Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (492 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
	PDE1B	Phosphodiesterase. (541 aa)
	GABRA1	Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (459 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2005 aa)
	TAS2R1	Taste receptor type 2. (299 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
	P2RX2	Purinergic receptor P2X 2. (323 aa)
	PKD2L1	Polycystin 2 like 1, transient receptor potential cation channel. (804 aa)
	TAS2R5	Taste receptor type 2. (296 aa)
	G1PYK1_MYOLU	Taste receptor type 2. (303 aa)
	GABRA5	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (434 aa)
	G1Q141_MYOLU	Uncharacterized protein. (2174 aa)
	LOC102431998	Uncharacterized protein; Belongs to the G-protein coupled receptor T2R family. (178 aa)
	P2RY4	Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (347 aa)
	LOC102425924	Taste receptor type 2. (305 aa)
	TAS2R40	Taste receptor type 2. (317 aa)
	TAS2R16	Taste receptor type 2. (299 aa)
	GNAT3	G protein subunit alpha transducin 3. (355 aa)
	LOC102440242	Taste receptor type 2. (300 aa)
	G1Q7B9_MYOLU	Uncharacterized protein. (109 aa)
	P2RY1	Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	PLCB1	Phosphoinositide phospholipase C. (726 aa)
	LOC102424215	Taste receptor type 2. (308 aa)
	GNG13	G protein subunit gamma 13. (67 aa)
	TAS2R38	Taste receptor type 2. (335 aa)
	HTR1D	G_PROTEIN_RECEP_F1_2 domain-containing protein. (377 aa)
	CHRM3	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
	TAS2R4	Taste receptor type 2. (300 aa)
	HCN4	Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1001 aa)
	TAS2R10	Taste receptor type 2. (299 aa)
	TAS2R39	Taste receptor type 2. (316 aa)
	G1QFL2_MYOLU	Taste receptor type 2. (304 aa)
	LOC102441167	Taste receptor type 2. (313 aa)
	CALHM1	Calcium homeostasis modulator 1. (345 aa)
	GABBR2	Gamma-aminobutyric acid type B receptor subunit 2. (835 aa)
	SCN2A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2019 aa)
	GABRA6	Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
	GRM1	Glutamate metabotropic receptor 1. (1205 aa)
	HTR1E	5-hydroxytryptamine receptor 1E. (365 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
	LOC102437885	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (387 aa)
	PDE1C	Phosphodiesterase. (670 aa)
	ASIC2	Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (567 aa)
	GABBR1	Gamma-aminobutyric acid type B receptor subunit 1; Belongs to the G-protein coupled receptor 3 family. (742 aa)
	SCN3A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1999 aa)

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY4	ADCY6	ENSMLUP00000013491	ENSMLUP00000009988	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.968
ADCY4	ADCY8	ENSMLUP00000013491	ENSMLUP00000011119	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.891
ADCY4	GNAT3	ENSMLUP00000013491	ENSMLUP00000018925	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha transducin 3.	0.788
ADCY4	GNB3	ENSMLUP00000013491	ENSMLUP00000006150	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 3.	0.888
ADCY4	GNG13	ENSMLUP00000013491	ENSMLUP00000019806	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit gamma 13.	0.887
ADCY4	PDE1A	ENSMLUP00000013491	ENSMLUP00000009073	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.882
ADCY4	PDE1B	ENSMLUP00000013491	ENSMLUP00000011818	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.882
ADCY4	PDE1C	ENSMLUP00000013491	ENSMLUP00000001892	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.882
ADCY4	PLCB3	ENSMLUP00000013491	ENSMLUP00000006407	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.592
ADCY4	PRKACA	ENSMLUP00000013491	ENSMLUP00000007530	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.938
ADCY4	PRKACB	ENSMLUP00000013491	ENSMLUP00000003022	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.938
ADCY6	ADCY4	ENSMLUP00000009988	ENSMLUP00000013491	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.968
ADCY6	ADCY8	ENSMLUP00000009988	ENSMLUP00000011119	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.882
ADCY6	GNAT3	ENSMLUP00000009988	ENSMLUP00000018925	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha transducin 3.	0.788
ADCY6	GNB3	ENSMLUP00000009988	ENSMLUP00000006150	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 3.	0.888
ADCY6	GNG13	ENSMLUP00000009988	ENSMLUP00000019806	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit gamma 13.	0.887
ADCY6	PDE1A	ENSMLUP00000009988	ENSMLUP00000009073	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.883
ADCY6	PDE1B	ENSMLUP00000009988	ENSMLUP00000011818	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.969
ADCY6	PDE1C	ENSMLUP00000009988	ENSMLUP00000001892	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.887
ADCY6	PLCB3	ENSMLUP00000009988	ENSMLUP00000006407	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.591