Your Input: | |
| | G1P265_MYOLU | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2547 aa) |
| | PLCD3 | Phosphoinositide phospholipase C. (593 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | G1NT50_MYOLU | Uncharacterized protein. (243 aa) |
| | NCOA3 | Nuclear receptor coactivator. (1408 aa) |
| | MED13L | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2056 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | MED14 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1456 aa) |
| | LOC102417711 | Sodium/potassium-transporting ATPase subunit alpha. (623 aa) |
| | G1NV71_MYOLU | Sodium/potassium-transporting ATPase subunit alpha. (988 aa) |
| | CREBBP | CREB binding protein. (2408 aa) |
| | PLCD4 | Phosphoinositide phospholipase C. (766 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (632 aa) |
| | G1NVZ4_MYOLU | Uncharacterized protein. (433 aa) |
| | PFKP | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (790 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2452 aa) |
| | MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (269 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (467 aa) |
| | MED30 | Mediator complex subunit 30. (149 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (408 aa) |
| | NOTCH2 | Notch receptor 2. (2463 aa) |
| | G1NZE8_MYOLU | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (512 aa) |
| | ACTBL2 | Actin beta like 2. (370 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa) |
| | MED24 | Mediator complex subunit 24. (925 aa) |
| | LOC102433374 | Uncharacterized protein. (374 aa) |
| | MED13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2177 aa) |
| | PIK3R2 | Uncharacterized protein. (730 aa) |
| | MYH15 | Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1496 aa) |
| | TSC2 | TSC complex subunit 2. (1809 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (179 aa) |
| | G1Q300_MYOLU | Uncharacterized protein. (601 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (557 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (814 aa) |
| | NOTCH3 | Notch receptor 3. (2210 aa) |
| | ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha. (986 aa) |
| | GATA4 | GATA binding protein 4. (240 aa) |
| | CSDE1 | Cold shock domain containing E1. (813 aa) |
| | NOTCH1 | Notch receptor 1. (1802 aa) |
| | G1P5Y1_MYOLU | Mitogen-activated protein kinase. (321 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1575 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (595 aa) |
| | MED12 | Mediator complex subunit 12. (2187 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1198 aa) |
| | BAD | BCL2 associated agonist of cell death. (174 aa) |
| | KAT2B | Lysine acetyltransferase 2B. (730 aa) |
| | PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (518 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (996 aa) |
| | G1P9Y9_MYOLU | Fork-head domain-containing protein. (483 aa) |
| | SLC16A2 | Solute carrier family 16 member 2. (399 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1053 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (243 aa) |
| | RHEBL1 | RHEB like 1. (183 aa) |
| | HDAC3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa) |
| | G1PBZ4_MYOLU | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (373 aa) |
| | CTNNB1 | Catenin beta 1. (782 aa) |
| | PIK3CA | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | MED4-2 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (234 aa) |
| | THRB | Thyroid hormone receptor beta. (482 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (416 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1275 aa) |
| | ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1052 aa) |
| | MDM2 | MDM2 proto-oncogene. (499 aa) |
| | ATP1B1 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa) |
| | STAT1 | Signal transducer and activator of transcription. (1171 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1218 aa) |
| | PLCD1 | Phosphoinositide phospholipase C. (616 aa) |
| | RXRA | Retinoid X receptor alpha. (460 aa) |
| | G1PGZ7_MYOLU | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (97 aa) |
| | G1PH02_MYOLU | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (122 aa) |
| | PFKL | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (752 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (370 aa) |
| | ATP1B3 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (245 aa) |
| | MED12L | Mediator complex subunit 12L. (2134 aa) |
| | MED17 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (652 aa) |
| | LOC102425233 | Uncharacterized protein. (335 aa) |
| | MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (833 aa) |
| | LOC102432706 | Phosphoinositide phospholipase C. (954 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (776 aa) |
| | RCAN3 | RCAN family member 3. (241 aa) |
| | SLC16A10 | Solute carrier family 16 member 10. (410 aa) |
| | TBC1D4 | TBC1 domain family member 4. (1139 aa) |
| | ATP1B4 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (355 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1464 aa) |
| | PLCL2 | Phosphoinositide phospholipase C. (1018 aa) |
| | SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (515 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | SIN3B | SIN3 transcription regulator family member B. (1161 aa) |
| | NCOA1 | Nuclear receptor coactivator. (1440 aa) |
| | RXRB | Retinoid X receptor beta. (532 aa) |
| | CCDC170 | Coiled-coil domain containing 170. (691 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (551 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa) |
| | G1PQI2_MYOLU | Sodium/potassium-transporting ATPase subunit alpha. (1029 aa) |
| | EP300 | E1A binding protein p300. (2412 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (826 aa) |
| | G1PS02_MYOLU | Uncharacterized protein. (197 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (969 aa) |
| | PRKCG | Protein kinase C gamma; Belongs to the protein kinase superfamily. (490 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | DIO2 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (73 aa) |
| | MYH8 | Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1891 aa) |
| | MYH4 | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1943 aa) |
| | MYH1 | Myosin heavy chain 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa) |
| | MYH2 | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa) |
| | MYH3 | Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa) |
| | PLCE1 | Phosphoinositide phospholipase C. (2267 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (967 aa) |
| | PLCZ1 | Phosphoinositide phospholipase C. (647 aa) |
| | G1PWD2_MYOLU | Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (169 aa) |
| | MYH7 | Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1936 aa) |
| | SLCO1C1 | Solute carrier organic anion transporter family member. (711 aa) |
| | PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (648 aa) |
| | PFKM | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (854 aa) |
| | G1PXS4_MYOLU | Uncharacterized protein. (146 aa) |
| | ERAS | ES cell expressed Ras. (229 aa) |
| | G1PYS3_MYOLU | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | G1PZ51_MYOLU | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa) |
| | G1PZA9_MYOLU | Uncharacterized protein. (537 aa) |
| | G1PZF4_MYOLU | Uncharacterized protein. (708 aa) |
| | SRC | Tyrosine-protein kinase. (543 aa) |
| | ACTL8 | Actin like 8; Belongs to the actin family. (367 aa) |
| | G1Q0Z1_MYOLU | Uncharacterized protein. (738 aa) |
| | G1Q1C5_MYOLU | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (51 aa) |
| | RXRG | Retinoid X receptor gamma. (258 aa) |
| | G1QFY8_MYOLU | Uncharacterized protein. (49 aa) |
| | G1QER2_MYOLU | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (360 aa) |
| | G1QEB5_MYOLU | Uncharacterized protein. (586 aa) |
| | G1QEB1_MYOLU | SH2 domain-containing protein. (266 aa) |
| | LOC102433258 | Uncharacterized protein. (118 aa) |
| | G1QCZ0_MYOLU | TAZ-type domain-containing protein. (636 aa) |
| | LOC102428025 | Uncharacterized protein. (311 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (440 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | ATP1B2 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa) |
| | G1QBB3_MYOLU | SH2 domain-containing protein. (270 aa) |
| | G1Q9T3_MYOLU | Uncharacterized protein. (72 aa) |
| | G1Q8T5_MYOLU | Uncharacterized protein. (80 aa) |
| | LOC102437790 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (848 aa) |
| | G1Q7H0_MYOLU | Uncharacterized protein. (544 aa) |
| | PLCB1 | Phosphoinositide phospholipase C. (726 aa) |
| | G1Q6V0_MYOLU | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (784 aa) |
