STRINGSTRING
RYR1 RYR1 G1PBZ4_MYOLU G1PBZ4_MYOLU PIK3R5 PIK3R5 PRKACA PRKACA PLCB2 PLCB2 ADCY5 ADCY5 MEF2C MEF2C PTGS2 PTGS2 MAPK7 MAPK7 CACNA2D1 CACNA2D1 PPP3CC PPP3CC G1PA19_MYOLU G1PA19_MYOLU GNAS GNAS PLA2G4A PLA2G4A CALM1 CALM1 CAMK4 CAMK4 SLC39A12 SLC39A12 CAMK1D CAMK1D PLCB3 PLCB3 PRKCB PRKCB KCNJ2 KCNJ2 MYL6 MYL6 MYL6B MYL6B RYR2 RYR2 G1P5Y1_MYOLU G1P5Y1_MYOLU NFATC3 NFATC3 ADCY9 ADCY9 CACNA1F CACNA1F G1P5B5_MYOLU G1P5B5_MYOLU CSDE1 CSDE1 PPP1R12A PPP1R12A GNAI1 GNAI1 KCNJ5 KCNJ5 PPP1CA PPP1CA CALML5 CALML5 RYR3 RYR3 CAMK1G CAMK1G RGS2 RGS2 GNAI3 GNAI3 PRKAG2 PRKAG2 PRKAG3 PRKAG3 PPP1CB PPP1CB GNAQ GNAQ FOS FOS EEF2K EEF2K LOC102433374 LOC102433374 CACNB4 CACNB4 PRKACB PRKACB ACTBL2 ACTBL2 PPP1R12C PPP1R12C PIK3CG PIK3CG GNAI2 GNAI2 CACNA2D4 CACNA2D4 MAP2K5 MAP2K5 NPR1 NPR1 CACNB2 CACNB2 ELK1 ELK1 PRKCA PRKCA PIK3R6 PIK3R6 NFATC1 NFATC1 PPP1R12B PPP1R12B JMJD7 JMJD7 G1QFY8_MYOLU G1QFY8_MYOLU G1QFL7_MYOLU G1QFL7_MYOLU G1QER2_MYOLU G1QER2_MYOLU G1QDP4_MYOLU G1QDP4_MYOLU LOC102440407 LOC102440407 CACNG3 CACNG3 NRAS NRAS G1QAY5_MYOLU G1QAY5_MYOLU G1Q9J5_MYOLU G1Q9J5_MYOLU KCNJ9 KCNJ9 G1NTT7_MYOLU G1NTT7_MYOLU PLA2G4F PLA2G4F PLA2G4D PLA2G4D G1NSR6_MYOLU G1NSR6_MYOLU G1Q8S3_MYOLU G1Q8S3_MYOLU ADCY7 ADCY7 NPR2 NPR2 PLCB1 PLCB1 CALM2 CALM2 GPR150 GPR150 LOC102436383 LOC102436383 LOC102420454 LOC102420454 LOC102441815 LOC102441815 G1Q560_MYOLU G1Q560_MYOLU G1Q555_MYOLU G1Q555_MYOLU G1Q4P8_MYOLU G1Q4P8_MYOLU LOC102430746 LOC102430746 KCNJ4 KCNJ4 G1Q2Q4_MYOLU G1Q2Q4_MYOLU G1Q234_MYOLU G1Q234_MYOLU PPP1CC PPP1CC G1Q1E4_MYOLU G1Q1E4_MYOLU ACTL8 ACTL8 SRC SRC ERAS ERAS LOC102433989 LOC102433989 RAF1 RAF1 KCNJ6 KCNJ6 GUCY1A2 GUCY1A2 CACNA1D CACNA1D CAMKK2 CAMKK2 G1PUW2_MYOLU G1PUW2_MYOLU OXTR OXTR LOC102419493 LOC102419493 KRAS KRAS CACNG2 CACNG2 ROCK2 ROCK2 PRKCG PRKCG PPP3CA PPP3CA PRKAB1 PRKAB1 LOC102419721 LOC102419721 LOC102423280 LOC102423280 ADCY4 ADCY4 NOS3 NOS3 NFATC2 NFATC2 G1PQ28_MYOLU G1PQ28_MYOLU PRKAA2 PRKAA2 EEF2 EEF2 PRKAA1 PRKAA1 CACNG1 CACNG1 CACNG4 CACNG4 CACNA1C CACNA1C ADCY3 ADCY3 PTRHD1 PTRHD1 ROCK1 ROCK1 RHOA RHOA ADCY2 ADCY2 CACNA2D3 CACNA2D3 ARSI ARSI CAMK2A CAMK2A CAMK1 CAMK1 CAMK2G CAMK2G PPP3CB PPP3CB CACNB1 CACNB1 PLCB4 PLCB4 ADCY8 ADCY8 G1PJN7_MYOLU G1PJN7_MYOLU G1PJJ0_MYOLU G1PJJ0_MYOLU MYLK MYLK ITPR3 ITPR3 LOC102441292 LOC102441292 MAP2K1 MAP2K1 LOC102432706 LOC102432706 PLA2G4E PLA2G4E LOC102425233 LOC102425233 GUCY1B1 GUCY1B1 ITPR2 ITPR2 GUCY1A1 GUCY1A1 MAPK3 MAPK3 NFATC4 NFATC4 MYLK4 MYLK4 CCND1 CCND1 PRKAG1 PRKAG1 TRPM2 TRPM2 CACNB3 CACNB3 ADCY6 ADCY6 CDKN1A CDKN1A KCNJ3 KCNJ3 CALM3 CALM3 CALML4 CALML4 CD38 CD38
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RYR1Ryanodine receptor 1. (4938 aa)
G1PBZ4_MYOLUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (373 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (856 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (243 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1215 aa)
MEF2CMyocyte enhancer factor 2C. (474 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (810 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (965 aa)
PPP3CCSerine/threonine-protein phosphatase. (500 aa)
G1PA19_MYOLUUncharacterized protein. (1508 aa)
GNASGNAS complex locus. (1058 aa)
PLA2G4APhospholipase A2. (742 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (159 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (423 aa)
SLC39A12Solute carrier family 39 member 12. (691 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID. (282 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1198 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (595 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
MYL6Myosin light chain 6. (151 aa)
MYL6BMyosin light chain 6B. (209 aa)
RYR2Ryanodine receptor 2. (4909 aa)
G1P5Y1_MYOLUMitogen-activated protein kinase. (321 aa)
NFATC3RHD domain-containing protein. (1062 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1943 aa)
G1P5B5_MYOLUUncharacterized protein. (635 aa)
CSDE1Cold shock domain containing E1. (813 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
GNAI1G protein subunit alpha i1. (319 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
CALML5Calmodulin like 5. (149 aa)
RYR3Ryanodine receptor 3. (4888 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (477 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (320 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (496 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (312 aa)
GNAQG protein subunit alpha q. (316 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
EEF2KEukaryotic elongation factor 2 kinase. (726 aa)
LOC102433374Uncharacterized protein. (374 aa)
CACNB4SH3 domain-containing protein. (471 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
ACTBL2Actin beta like 2. (370 aa)
PPP1R12CProtein phosphatase 1 regulatory subunit 12C. (589 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
GNAI2G protein subunit alpha i2. (317 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1094 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (393 aa)
NPR1Guanylate cyclase. (809 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (549 aa)
ELK1ETS transcription factor ELK1. (461 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (632 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (509 aa)
NFATC1Nuclear factor of activated T cells 1. (928 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (802 aa)
JMJD7Jumonji domain containing 7. (313 aa)
G1QFY8_MYOLUUncharacterized protein. (49 aa)
G1QFL7_MYOLUUncharacterized protein. (259 aa)
G1QER2_MYOLUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (360 aa)
G1QDP4_MYOLUUncharacterized protein. (154 aa)
LOC102440407Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (246 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
G1QAY5_MYOLUUncharacterized protein. (639 aa)
G1Q9J5_MYOLUAMPK1_CBM domain-containing protein. (183 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (397 aa)
G1NTT7_MYOLUProtein kinase domain-containing protein. (310 aa)
PLA2G4FPhospholipase A2. (839 aa)
PLA2G4DPhospholipase A2. (827 aa)
G1NSR6_MYOLUUncharacterized protein. (175 aa)
G1Q8S3_MYOLUUncharacterized protein. (414 aa)
ADCY7Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (574 aa)
NPR2Guanylate cyclase. (1057 aa)
PLCB1Phosphoinositide phospholipase C. (726 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
GPR150G_PROTEIN_RECEP_F1_2 domain-containing protein. (369 aa)
LOC102436383SER_THR_PHOSPHATASE domain-containing protein. (321 aa)
LOC102420454MIR domain-containing protein. (102 aa)
LOC102441815Guanylate cyclase. (1092 aa)
G1Q560_MYOLUUncharacterized protein. (430 aa)
G1Q555_MYOLUUncharacterized protein. (175 aa)
G1Q4P8_MYOLUUncharacterized protein; Belongs to the calmodulin family. (145 aa)
LOC102430746Uncharacterized protein. (193 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (442 aa)
G1Q2Q4_MYOLUUncharacterized protein. (194 aa)
G1Q234_MYOLUBZIP domain-containing protein; Belongs to the bZIP family. (204 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (324 aa)
G1Q1E4_MYOLUTr-type G domain-containing protein. (569 aa)
ACTL8Actin like 8; Belongs to the actin family. (367 aa)
SRCTyrosine-protein kinase. (543 aa)
ERASES cell expressed Ras. (229 aa)
LOC102433989Uncharacterized protein. (242 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (424 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (630 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2018 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (578 aa)
G1PUW2_MYOLUGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (738 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (388 aa)
LOC102419493Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (256 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1341 aa)
PRKCGProtein kinase C gamma; Belongs to the protein kinase superfamily. (490 aa)
PPP3CASerine/threonine-protein phosphatase. (440 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
LOC102419721Phospholipase A2. (812 aa)
LOC102423280Uncharacterized protein. (431 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
NFATC2Nuclear factor of activated T cells 2. (878 aa)
G1PQ28_MYOLUAMPKBI domain-containing protein. (221 aa)
PRKAA2Non-specific serine/threonine protein kinase. (528 aa)
EEF2Tr-type G domain-containing protein. (860 aa)
PRKAA1Non-specific serine/threonine protein kinase. (517 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (247 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2005 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1151 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1356 aa)
RHOAUncharacterized protein. (193 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (852 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1091 aa)
ARSIArylsulfatase family member I. (571 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha. (511 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (558 aa)
PPP3CBSerine/threonine-protein phosphatase. (514 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (606 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
G1PJN7_MYOLUUncharacterized protein. (113 aa)
G1PJJ0_MYOLUIon_trans domain-containing protein. (561 aa)
MYLKMyosin light chain kinase. (1946 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2048 aa)
LOC102441292Uncharacterized protein. (153 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
LOC102432706Phosphoinositide phospholipase C. (954 aa)
PLA2G4EPhospholipase A2. (805 aa)
LOC102425233Uncharacterized protein. (335 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (621 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2648 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
MAPK3Mitogen-activated protein kinase. (370 aa)
NFATC4Nuclear factor of activated T cells 4. (869 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (336 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (329 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1557 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (483 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1165 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (192 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (148 aa)
CALML4Calmodulin like 4. (196 aa)
CD38CD38 molecule. (308 aa)
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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