STRINGSTRING
GNA13 GNA13 G1NSX7_MYOLU G1NSX7_MYOLU RUNX2 RUNX2 LOC102428376 LOC102428376 LOC102421372 LOC102421372 SLC34A2 SLC34A2 VDR VDR NACA NACA LRP5 LRP5 MMP25 MMP25 PRKCA PRKCA GNAI2 GNAI2 ARRB2 ARRB2 MMP16 MMP16 GCM1 GCM1 HBEGF HBEGF SLC9A3R1 SLC9A3R1 PRKACB PRKACB PLD1 PLD1 FOS FOS GNAQ GNAQ PDE4C PDE4C GNAI3 GNAI3 MMP24 MMP24 GCM2 GCM2 GNAI1 GNAI1 G1P5B5_MYOLU G1P5B5_MYOLU ADCY9 ADCY9 CYP27B1 CYP27B1 G1P5Y1_MYOLU G1P5Y1_MYOLU SOST SOST LOC102427353 LOC102427353 PRKCB PRKCB GNA11 GNA11 PLCB3 PLCB3 BRAF BRAF GNAS GNAS G1PA19_MYOLU G1PA19_MYOLU MEF2C MEF2C ADCY5 ADCY5 PLCB2 PLCB2 PRKACA PRKACA CYP24A1 CYP24A1 PTHLH PTHLH NR4A2 NR4A2 CREB3L3 CREB3L3 AKAP13 AKAP13 TNFSF11 TNFSF11 PDE4B PDE4B CASR CASR SLC34A1 SLC34A1 PTH1R PTH1R CREB3L1 CREB3L1 RXRA RXRA CDKN1A CDKN1A LRP6 LRP6 TRPV5 TRPV5 ADCY6 ADCY6 ARHGEF11 ARHGEF11 MAPK3 MAPK3 ITPR2 ITPR2 CREB3 CREB3 LOC102432706 LOC102432706 MAP2K1 MAP2K1 ITPR3 ITPR3 G1PJJ0_MYOLU G1PJJ0_MYOLU ADCY8 ADCY8 PLCB4 PLCB4 MMP14 MMP14 CREB3L4 CREB3L4 KL KL ADCY2 ADCY2 CREB5 CREB5 RHOA RHOA MEF2D MEF2D PTRHD1 PTRHD1 ADCY3 ADCY3 RXRB RXRB ARAF ARAF GATA3 GATA3 ADCY4 ADCY4 PDE4A PDE4A G1PRL6_MYOLU G1PRL6_MYOLU PRKCG PRKCG PLD2 PLD2 ATF2 ATF2 CREB1 CREB1 MEF2A MEF2A PDE4D PDE4D EGR1 EGR1 G1PVR1_MYOLU G1PVR1_MYOLU SP1 SP1 RAF1 RAF1 LOC102433989 LOC102433989 CREB3L2 CREB3L2 BGLAP BGLAP FGF23 FGF23 G1Q151_MYOLU G1Q151_MYOLU G1Q1U3_MYOLU G1Q1U3_MYOLU G1Q2Q4_MYOLU G1Q2Q4_MYOLU LOC102430746 LOC102430746 ATF6B ATF6B LOC102431899 LOC102431899 LOC102420454 LOC102420454 PLCB1 PLCB1 ADCY7 ADCY7 G1Q8D0_MYOLU G1Q8D0_MYOLU G1QAB2_MYOLU G1QAB2_MYOLU G1QCQ8_MYOLU G1QCQ8_MYOLU G1QER2_MYOLU G1QER2_MYOLU ATF4 ATF4 ARRB1 ARRB1 GNA12 GNA12 G1QFY8_MYOLU G1QFY8_MYOLU RXRG RXRG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNA13G protein subunit alpha 13. (284 aa)
G1NSX7_MYOLUZnMc domain-containing protein. (411 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (358 aa)
LOC102428376Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
LOC102421372Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. (111 aa)
SLC34A2Uncharacterized protein. (696 aa)
VDRVitamin D receptor. (427 aa)
NACANAC-A/B domain-containing protein. (215 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1607 aa)
MMP25Matrix metallopeptidase 25. (574 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (632 aa)
GNAI2G protein subunit alpha i2. (317 aa)
ARRB2Arrestin_C domain-containing protein. (306 aa)
MMP16Matrix metallopeptidase 16. (562 aa)
GCM1Glial cells missing transcription factor 1. (430 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
PLD1Phospholipase. (962 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
GNAQG protein subunit alpha q. (316 aa)
PDE4CPhosphodiesterase. (792 aa)
GNAI3G protein subunit alpha i3. (354 aa)
MMP24Matrix metallopeptidase 24. (564 aa)
GCM2Glial cells missing transcription factor 2. (490 aa)
GNAI1G protein subunit alpha i1. (319 aa)
G1P5B5_MYOLUUncharacterized protein. (635 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
G1P5Y1_MYOLUMitogen-activated protein kinase. (321 aa)
SOSTSclerostin. (213 aa)
LOC102427353ZnMc domain-containing protein. (470 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (595 aa)
GNA11G protein subunit alpha 11. (339 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1198 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (792 aa)
GNASGNAS complex locus. (1058 aa)
G1PA19_MYOLUUncharacterized protein. (1508 aa)
MEF2CMyocyte enhancer factor 2C. (474 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1215 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (243 aa)
CYP24A1Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (514 aa)
PTHLHParathyroid hormone like hormone. (176 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (612 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (473 aa)
AKAP13A-kinase anchoring protein 13. (2797 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (323 aa)
PDE4BPhosphodiesterase. (665 aa)
CASRCalcium sensing receptor. (1075 aa)
SLC34A1Solute carrier family 34 member 1. (639 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (567 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (486 aa)
RXRARetinoid X receptor alpha. (460 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (192 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1609 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (730 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1165 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1552 aa)
MAPK3Mitogen-activated protein kinase. (370 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2648 aa)
CREB3cAMP responsive element binding protein 3. (365 aa)
LOC102432706Phosphoinositide phospholipase C. (954 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2048 aa)
G1PJJ0_MYOLUIon_trans domain-containing protein. (561 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
MMP14Matrix metallopeptidase 14. (581 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (394 aa)
KLKlotho. (1008 aa)
ADCY2Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (852 aa)
CREB5cAMP responsive element binding protein 5. (276 aa)
RHOAUncharacterized protein. (193 aa)
MEF2DMyocyte enhancer factor 2D. (524 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1151 aa)
RXRBRetinoid X receptor beta. (532 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (613 aa)
GATA3GATA binding protein 3. (443 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
PDE4APhosphodiesterase. (859 aa)
G1PRL6_MYOLUUncharacterized protein. (263 aa)
PRKCGProtein kinase C gamma; Belongs to the protein kinase superfamily. (490 aa)
PLD2Phospholipase. (929 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
MEF2AMyocyte enhancer factor 2A. (496 aa)
PDE4DPhosphodiesterase. (584 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (540 aa)
G1PVR1_MYOLUPDE4_UCR domain-containing protein. (189 aa)
SP1Sp1 transcription factor. (789 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
LOC102433989Uncharacterized protein. (242 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (526 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (102 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (248 aa)
G1Q151_MYOLUZnMc domain-containing protein. (458 aa)
G1Q1U3_MYOLUNAC-A/B domain-containing protein. (162 aa)
G1Q2Q4_MYOLUUncharacterized protein. (194 aa)
LOC102430746Uncharacterized protein. (193 aa)
ATF6BActivating transcription factor 6 beta. (653 aa)
LOC102431899Arrestin_C domain-containing protein. (91 aa)
LOC102420454MIR domain-containing protein. (102 aa)
PLCB1Phosphoinositide phospholipase C. (726 aa)
ADCY7Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (574 aa)
G1Q8D0_MYOLUUncharacterized protein. (603 aa)
G1QAB2_MYOLUUncharacterized protein. (92 aa)
G1QCQ8_MYOLUUncharacterized protein. (333 aa)
G1QER2_MYOLUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (360 aa)
ATF4BZIP domain-containing protein. (347 aa)
ARRB1Arrestin beta 1. (414 aa)
GNA12Uncharacterized protein. (157 aa)
G1QFY8_MYOLUUncharacterized protein. (49 aa)
RXRGRetinoid X receptor gamma. (258 aa)
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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