STRINGSTRING
ATF2 ATF2 SLC6A3 SLC6A3 GRIN2A GRIN2A PPP1R1B PPP1R1B CDK5 CDK5 CREB5 CREB5 CREB3L4 CREB3L4 SLC18A1 SLC18A1 DRD2 DRD2 GRIN3B GRIN3B CREB3 CREB3 RGS9 RGS9 RGS11 RGS11 CREB3L1 CREB3L1 GRIN2B GRIN2B FOSB FOSB RELA RELA CREB3L3 CREB3L3 PRKACA PRKACA ADCY5 ADCY5 GNAS GNAS GRIN3A GRIN3A NFKB1 NFKB1 GNAI1 GNAI1 SLC18A2 SLC18A2 GRM2 GRM2 GNAI3 GNAI3 PRKACB PRKACB PDYN PDYN DLG4 DLG4 GNAI2 GNAI2 MAOB MAOB MAOA MAOA G1NUB7_MYOLU G1NUB7_MYOLU ATF4 ATF4 CDK5R2 CDK5R2 G1QCQ8_MYOLU G1QCQ8_MYOLU G1Q913_MYOLU G1Q913_MYOLU ATF6B ATF6B G1Q415_MYOLU G1Q415_MYOLU G1Q3Q5_MYOLU G1Q3Q5_MYOLU G1Q234_MYOLU G1Q234_MYOLU LOC102418872 LOC102418872 CDK5R1 CDK5R1 CREB3L2 CREB3L2 LOC102433989 LOC102433989 LOC102430009 LOC102430009 GRIA2 GRIA2 DRD1 DRD1 G1PV98_MYOLU G1PV98_MYOLU CREB1 CREB1 BDNF BDNF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1324 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (124 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (294 aa)
CREB5cAMP responsive element binding protein 5. (276 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (394 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (454 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1018 aa)
CREB3cAMP responsive element binding protein 3. (365 aa)
RGS9Regulator of G protein signaling 9. (670 aa)
RGS11Regulator of G protein signaling 11. (463 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (486 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1345 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
RELARELA proto-oncogene, NF-kB subunit. (545 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (473 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (243 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1215 aa)
GNASGNAS complex locus. (1058 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1112 aa)
NFKB1Nuclear factor kappa B subunit 1. (972 aa)
GNAI1G protein subunit alpha i1. (319 aa)
SLC18A2Solute carrier family 18 member A2. (516 aa)
GRM2Glutamate metabotropic receptor 2. (870 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
PDYNProdynorphin. (252 aa)
DLG4Discs large MAGUK scaffold protein 4. (559 aa)
GNAI2G protein subunit alpha i2. (317 aa)
MAOBAmine oxidase. (530 aa)
MAOAAmine oxidase. (526 aa)
G1NUB7_MYOLUUncharacterized protein. (338 aa)
ATF4BZIP domain-containing protein. (347 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (369 aa)
G1QCQ8_MYOLUUncharacterized protein. (333 aa)
G1Q913_MYOLUUncharacterized protein. (40 aa)
ATF6BActivating transcription factor 6 beta. (653 aa)
G1Q415_MYOLUUncharacterized protein. (48 aa)
G1Q3Q5_MYOLUUncharacterized protein. (38 aa)
G1Q234_MYOLUBZIP domain-containing protein; Belongs to the bZIP family. (204 aa)
LOC102418872Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (391 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (526 aa)
LOC102433989Uncharacterized protein. (242 aa)
LOC102430009Lig_chan-Glu_bd domain-containing protein. (536 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (449 aa)
G1PV98_MYOLUG_PROTEIN_RECEP_F3_4 domain-containing protein. (455 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (247 aa)
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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