52 items (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PDYN	Prodynorphin. (252 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	GRM2	Glutamate metabotropic receptor 2. (870 aa)
	SLC18A2	Solute carrier family 18 member A2. (516 aa)
	GNAI1	G protein subunit alpha i1. (319 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (972 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1112 aa)
	GNAS	GNAS complex locus. (1058 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1215 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (243 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
	BDNF	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (247 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	G1PV98_MYOLU	G_PROTEIN_RECEP_F3_4 domain-containing protein. (455 aa)
	DRD1	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (449 aa)
	CREB3L1	cAMP responsive element binding protein 3 like 1. (486 aa)
	GRIN2B	Glutamate ionotropic receptor NMDA type subunit 2B. (1345 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A. (1324 aa)
	FOSB	FosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (545 aa)
	PPP1R1B	Protein phosphatase 1 regulatory inhibitor subunit 1B. (124 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (294 aa)
	CREB5	cAMP responsive element binding protein 5. (276 aa)
	CREB3L4	cAMP responsive element binding protein 3 like 4. (394 aa)
	SLC18A1	Solute carrier family 18 member A1. (525 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (454 aa)
	GRIN3B	Glutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1018 aa)
	CREB3	cAMP responsive element binding protein 3. (365 aa)
	RGS9	Regulator of G protein signaling 9. (670 aa)
	CREB3L3	cAMP responsive element binding protein 3 like 3. (473 aa)
	RGS11	Regulator of G protein signaling 11. (463 aa)
	ATF4	BZIP domain-containing protein. (347 aa)
	CDK5R2	Cyclin-dependent kinase 5 activator. (369 aa)
	G1QCQ8_MYOLU	Uncharacterized protein. (333 aa)
	G1Q913_MYOLU	Uncharacterized protein. (40 aa)
	ATF6B	Activating transcription factor 6 beta. (653 aa)
	G1Q415_MYOLU	Uncharacterized protein. (48 aa)
	G1Q3Q5_MYOLU	Uncharacterized protein. (38 aa)
	G1Q234_MYOLU	BZIP domain-containing protein; Belongs to the bZIP family. (204 aa)
	LOC102418872	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (391 aa)
	CDK5R1	Cyclin-dependent kinase 5 activator. (307 aa)
	CREB3L2	cAMP responsive element binding protein 3 like 2. (526 aa)
	LOC102433989	Uncharacterized protein. (242 aa)
	LOC102430009	Lig_chan-Glu_bd domain-containing protein. (536 aa)
	GRIA2	Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa)
	G1NUB7_MYOLU	Uncharacterized protein. (338 aa)
	MAOA	Amine oxidase. (526 aa)
	MAOB	Amine oxidase. (530 aa)
	GNAI2	G protein subunit alpha i2. (317 aa)
	DLG4	Discs large MAGUK scaffold protein 4. (559 aa)

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	DRD2	ENSMLUP00000007516	ENSMLUP00000010834	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.436
ADCY5	GNAI1	ENSMLUP00000007516	ENSMLUP00000004841	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i1.	0.906
ADCY5	GNAI2	ENSMLUP00000007516	ENSMLUP00000002148	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i2.	0.906
ADCY5	GNAI3	ENSMLUP00000007516	ENSMLUP00000003976	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i3.	0.906
ADCY5	GNAS	ENSMLUP00000007516	ENSMLUP00000007043	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS complex locus.	0.999
ADCY5	LOC102433989	ENSMLUP00000007516	ENSMLUP00000016320	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.882
ADCY5	PRKACA	ENSMLUP00000007516	ENSMLUP00000007530	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.923
ADCY5	PRKACB	ENSMLUP00000007516	ENSMLUP00000003022	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.923
ADCY5	RGS9	ENSMLUP00000007516	ENSMLUP00000009782	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Regulator of G protein signaling 9.	0.470
ATF2	ATF4	ENSMLUP00000014324	ENSMLUP00000022230	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	BZIP domain-containing protein.	0.902
ATF2	ATF6B	ENSMLUP00000014324	ENSMLUP00000018820	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Activating transcription factor 6 beta.	0.944
ATF2	CREB1	ENSMLUP00000014324	ENSMLUP00000014684	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 1.	0.964
ATF2	CREB3	ENSMLUP00000014324	ENSMLUP00000010554	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 3.	0.944
ATF2	CREB3L1	ENSMLUP00000014324	ENSMLUP00000008952	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 3 like 1.	0.886
ATF2	CREB3L2	ENSMLUP00000014324	ENSMLUP00000016542	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 3 like 2.	0.891
ATF2	CREB3L3	ENSMLUP00000014324	ENSMLUP00000007936	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 3 like 3.	0.883
ATF2	CREB3L4	ENSMLUP00000014324	ENSMLUP00000012096	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 3 like 4.	0.882
ATF2	CREB5	ENSMLUP00000014324	ENSMLUP00000012560	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 5.	0.975
ATF2	FOSB	ENSMLUP00000014324	ENSMLUP00000008203	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	FosB proto-oncogene, AP-1 transcription factor subunit.	0.538
ATF2	G1Q234_MYOLU	ENSMLUP00000014324	ENSMLUP00000017767	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	BZIP domain-containing protein; Belongs to the bZIP family.	0.999