STRINGSTRING
BAX BAX CDC42 CDC42 G1QEZ1_MYOLU G1QEZ1_MYOLU G1QER2_MYOLU G1QER2_MYOLU G1QEB1_MYOLU G1QEB1_MYOLU RAD51 RAD51 G1QDT5_MYOLU G1QDT5_MYOLU G1QBB3_MYOLU G1QBB3_MYOLU IKBKG IKBKG G1Q9T3_MYOLU G1Q9T3_MYOLU CDK4 CDK4 G1Q8T5_MYOLU G1Q8T5_MYOLU LOC102437790 LOC102437790 G1Q7Q1_MYOLU G1Q7Q1_MYOLU G1Q7N0_MYOLU G1Q7N0_MYOLU G1Q1Q1_MYOLU G1Q1Q1_MYOLU LOC102430620 LOC102430620 G1PZT1_MYOLU G1PZT1_MYOLU G1PZ51_MYOLU G1PZ51_MYOLU RAF1 RAF1 DDB2 DDB2 TGFBR2 TGFBR2 G1PWX7_MYOLU G1PWX7_MYOLU STAT3 STAT3 CHUK CHUK TGFA TGFA KRAS KRAS POLK POLK PLD2 PLD2 EGF EGF PIK3R1 PIK3R1 E2F1 E2F1 ERBB2 ERBB2 TGFBR1 TGFBR1 MAPK10 MAPK10 ARAF ARAF MAPK8 MAPK8 VEGFA VEGFA AKT3 AKT3 SMAD4 SMAD4 RALBP1 RALBP1 BRCA2 BRCA2 TGFB3 TGFB3 TGFB1 TGFB1 RAC2 RAC2 CDK6 CDK6 MAP2K1 MAP2K1 GADD45G GADD45G MAPK3 MAPK3 CCND1 CCND1 CDKN1A CDKN1A STAT1 STAT1 IKBKB IKBKB RAC1 RAC1 CASP9 CASP9 RALA RALA GADD45B GADD45B PIK3CA PIK3CA SMAD2 SMAD2 E2F2 E2F2 RELA RELA RB1 RB1 PIK3CD PIK3CD ARHGEF6 ARHGEF6 JAK1 JAK1 BRAF BRAF BCL2L1 BCL2L1 BAD BAD TP53 TP53 NFKB1 NFKB1 G1P5Y1_MYOLU G1P5Y1_MYOLU MAPK9 MAPK9 G1P5B5_MYOLU G1P5B5_MYOLU RALB RALB RPS6KB2 RPS6KB2 PIK3CB PIK3CB TGFB2 TGFB2 G1NVZ4_MYOLU G1NVZ4_MYOLU E2F3 E2F3 SMAD3 SMAD3 AKT2 AKT2 G1NZD6_MYOLU G1NZD6_MYOLU PLD1 PLD1 RPS6KB1 RPS6KB1 PIK3R2 PIK3R2 G1P265_MYOLU G1P265_MYOLU GADD45A GADD45A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BAXBCL2 associated X, apoptosis regulator. (193 aa)
CDC42Cell division cycle 42. (191 aa)
G1QEZ1_MYOLUProtein kinase C. (646 aa)
G1QER2_MYOLUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (360 aa)
G1QEB1_MYOLUSH2 domain-containing protein. (266 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (350 aa)
G1QDT5_MYOLURas-GEF domain-containing protein. (527 aa)
G1QBB3_MYOLUSH2 domain-containing protein. (270 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (425 aa)
G1Q9T3_MYOLUUncharacterized protein. (72 aa)
CDK4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (303 aa)
G1Q8T5_MYOLUUncharacterized protein. (80 aa)
LOC102437790Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (848 aa)
G1Q7Q1_MYOLUNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (443 aa)
G1Q7N0_MYOLUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
G1Q1Q1_MYOLURas-GEF domain-containing protein. (584 aa)
LOC102430620Uncharacterized protein. (226 aa)
G1PZT1_MYOLUUncharacterized protein. (75 aa)
G1PZ51_MYOLUCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
G1PWX7_MYOLUUncharacterized protein. (871 aa)
STAT3Signal transducer and activator of transcription. (773 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (746 aa)
TGFATransforming growth factor alpha. (128 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
POLKDNA polymerase kappa. (866 aa)
PLD2Phospholipase. (929 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1178 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
E2F1E2F transcription factor 1. (433 aa)
ERBB2Receptor protein-tyrosine kinase. (1244 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (471 aa)
MAPK10Mitogen-activated protein kinase. (422 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (613 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
VEGFAPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (216 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa)
SMAD4Mothers against decapentaplegic homolog. (554 aa)
RALBP1RalA binding protein 1. (654 aa)
BRCA2BRCA2 DNA repair associated. (3376 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (449 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
RAC2Rac family small GTPase 2. (192 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
GADD45GGrowth arrest and DNA damage inducible gamma. (159 aa)
MAPK3Mitogen-activated protein kinase. (370 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (192 aa)
STAT1Signal transducer and activator of transcription. (1171 aa)
IKBKBUncharacterized protein. (756 aa)
RAC1Rac family small GTPase 1. (211 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (416 aa)
RALARAS like proto-oncogene A. (206 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (160 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1070 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
E2F2E2F transcription factor 2. (436 aa)
RELARELA proto-oncogene, NF-kB subunit. (545 aa)
RB1RB transcriptional corepressor 1. (882 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1053 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (777 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (792 aa)
BCL2L1BCL2 like 1. (233 aa)
BADBCL2 associated agonist of cell death. (174 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa)
NFKB1Nuclear factor kappa B subunit 1. (972 aa)
G1P5Y1_MYOLUMitogen-activated protein kinase. (321 aa)
MAPK9Mitogen-activated protein kinase. (423 aa)
G1P5B5_MYOLUUncharacterized protein. (635 aa)
RALBRAS like proto-oncogene B. (229 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (487 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
G1NVZ4_MYOLUUncharacterized protein. (433 aa)
E2F3E2F transcription factor 3. (334 aa)
SMAD3Mothers against decapentaplegic homolog. (395 aa)
AKT2Non-specific serine/threonine protein kinase. (467 aa)
G1NZD6_MYOLURas-GEF domain-containing protein. (588 aa)
PLD1Phospholipase. (962 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
PIK3R2Uncharacterized protein. (730 aa)
G1P265_MYOLUSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2547 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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