STRINGSTRING
aroC aroC AJC48340.1 AJC48340.1 trpF trpF AJC48378.1 AJC48378.1 trpD trpD AJC48392.1 AJC48392.1 AJC48393.1 AJC48393.1 trpB trpB trpA trpA AJC48490.1 AJC48490.1 metK metK AJC48642.1 AJC48642.1 AJC48661.1 AJC48661.1 AJC48680.1 AJC48680.1 AJC48681.1 AJC48681.1 AJC48734.1 AJC48734.1 aroA aroA AJC48807.1 AJC48807.1 AJC48836.1 AJC48836.1 AJC48839.1 AJC48839.1 AJC48877.1 AJC48877.1 pheA pheA AJC48885.1 AJC48885.1 AJC48931.1 AJC48931.1 AJC48932.1 AJC48932.1 AJC48978.1 AJC48978.1 AJC49115.1 AJC49115.1 aroB aroB aroK aroK AJC49136.1 AJC49136.1 serC serC AJC49263.1 AJC49263.1 AJC49289.1 AJC49289.1 AJC49290.1 AJC49290.1 aroQ aroQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (352 aa)
AJC48340.1Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (257 aa)
trpFIndole-3-glycerol phosphate synthase; Monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (453 aa)
AJC48378.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (335 aa)
AJC48392.1Anthranilate synthase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
AJC48393.1With component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (516 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (396 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (268 aa)
AJC48490.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (440 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (386 aa)
AJC48642.1Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family. (368 aa)
AJC48661.1Cyclohexadienyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
AJC48680.1Carbon-nitrogen hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
AJC48681.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
AJC48734.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (426 aa)
AJC48807.1Asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
AJC48836.1Asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AJC48839.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
AJC48877.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
pheAPrephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AJC48885.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (457 aa)
AJC48931.1Chloroperoxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
AJC48932.1Anthranilate synthase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
AJC48978.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (411 aa)
AJC49115.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (357 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (176 aa)
AJC49136.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
serCMFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (350 aa)
AJC49263.1Aspartate aminotransferase; Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
AJC49289.1Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
AJC49290.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (154 aa)
Your Current Organism:
Allofrancisella guangzhouensis
NCBI taxonomy Id: 594679
Other names: A. guangzhouensis, ATCC BAA-2361, Allofrancisella guangzhouensis (Qu et al. 2013) Qu et al. 2016, CCUG 60119, Francisella guangzhouensis, Francisella guangzhouensis Qu et al. 2013, Francisella sp. 08HL01032, Francisella sp. 10HL1960, Francisella sp. 10HP82-6, NCTC 13503, strain 08HL01032
Server load: low (26%) [HD]