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lysA lysA gapA gapA lpdA-2 lpdA-2 dapB dapB dapA dapA sucD sucD thrA thrA thrB thrB thrC thrC aceF aceF argD argD ackA ackA pta pta lpdA lpdA dapD dapD sucC sucC ACU52796.1 ACU52796.1 tkt-2 tkt-2 tkt tkt lysC lysC fbaA fbaA dapF dapF acoA acoA prsA prsA ACU52755.1 ACU52755.1 fumC fumC gltX gltX acoB acoB asd asd ACU52897.1 ACU52897.1 sucB sucB sucA sucA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (402 aa)
gapAGlyceraldehyde 3-phosphate dehydrogenase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa)
lpdA-2Dihydrolipoamide dehydrogenase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770. (467 aa)
dapBDihydrodipicolinate reductase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770; Belongs to the DapB family. (243 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa)
thrAAspartokinase/homoserine dehydrogenase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770. (819 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (310 aa)
thrCThreonine synthase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770. (437 aa)
aceFDihydrolipoamide acyltransferase E2 component; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770. (376 aa)
argDAcetylornithine aminotransferase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (386 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (402 aa)
ptaPhosphate acetyltransferase; Predicted based on similarity to TIGRFAM pta and related proteins in nr. (332 aa)
lpdADihydrolipoamide dehydrogenase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770. (467 aa)
dapD2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770; Belongs to the transferase hexapeptide repeat family. (274 aa)
sucCsuccinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
ACU52796.1Molybdopterin oxidoreductase, iron-sulfur binding subunit; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770. (983 aa)
tkt-2Putative transketolase, C-terminal subunit; Predicted based on similarity to PFAM Transketolase_C and related proteins in nr. (320 aa)
tktPutative transketolase, N-terminal subunit; Predicted based on similarity to PFAM Transketolase_N and related proteins in nr. (283 aa)
lysCPutative aspartate kinase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770; Belongs to the aspartokinase family. (410 aa)
fbaAFructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (349 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (263 aa)
acoAPyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (333 aa)
prsARibose-phosphate pyrophosphokinase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770. (301 aa)
ACU52755.1Putative peptidase U32; Predicted based on similarity to PFAM Peptidase_U32 and related proteins in nr. (416 aa)
fumCPutative fumarate hydratase; Predicted based on weak similarity to TIGRMFAM fumC_II and related proteins in nr. (376 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (487 aa)
acoBPutative pyruvate dehydrogenase E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
asdAspartate semialdehyde dehydrogenase; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770; Belongs to the aspartate-semialdehyde dehydrogenase family. (331 aa)
ACU52897.1Conserved hypothetical protein; Predicted based on similarity to related proteins in nr. (102 aa)
sucB2-oxoglutarate dehydrogenase, E2 component; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770. (369 aa)
sucA2-oxoglutarate dehydrogenase, E1 component; Predicted based on similarity to protein in genome with GenBank Accession Number CP000770. (900 aa)
Your Current Organism:
Sulcia muelleri SMDSEM
NCBI taxonomy Id: 595499
Other names: C. Sulcia muelleri SMDSEM, Candidatus Sulcia muelleri SMDSEM, Candidiatus Sulcia muelleri str. SMDSEM, Candidiatus Sulcia muelleri strain SMDSEM
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