node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAOG_000143 | CAOG_000754 | A0A0D2WI06 | A0A0D2U7V4 | Origin recognition complex subunit 2. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.458 |
CAOG_000143 | CAOG_002048 | A0A0D2WI06 | A0A0D2VL30 | Origin recognition complex subunit 2. | Uncharacterized protein. | 0.997 |
CAOG_000143 | CAOG_005056 | A0A0D2WI06 | A0A0D2WSH5 | Origin recognition complex subunit 2. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.997 |
CAOG_000143 | CAOG_005062 | A0A0D2WI06 | A0A0D2X3J5 | Origin recognition complex subunit 2. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.998 |
CAOG_000143 | CAOG_007159 | A0A0D2WI06 | A0A0D2UPG4 | Origin recognition complex subunit 2. | Origin recognition complex ORC subunit 3. | 0.998 |
CAOG_000143 | CAOG_008193 | A0A0D2WI06 | A0A0D2UT94 | Origin recognition complex subunit 2. | Origin recognition complex. | 0.999 |
CAOG_000754 | CAOG_000143 | A0A0D2U7V4 | A0A0D2WI06 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Origin recognition complex subunit 2. | 0.458 |
CAOG_000754 | CAOG_001818 | A0A0D2U7V4 | A0A0D2VM00 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone H2B; Belongs to the histone H2B family. | 0.999 |
CAOG_000754 | CAOG_005056 | A0A0D2U7V4 | A0A0D2WSH5 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.961 |
CAOG_000754 | CAOG_007159 | A0A0D2U7V4 | A0A0D2UPG4 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Origin recognition complex ORC subunit 3. | 0.438 |
CAOG_000754 | CAOG_008193 | A0A0D2U7V4 | A0A0D2UT94 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Origin recognition complex. | 0.434 |
CAOG_001818 | CAOG_000754 | A0A0D2VM00 | A0A0D2U7V4 | Histone H2B; Belongs to the histone H2B family. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.999 |
CAOG_001818 | CAOG_005056 | A0A0D2VM00 | A0A0D2WSH5 | Histone H2B; Belongs to the histone H2B family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.828 |
CAOG_002048 | CAOG_000143 | A0A0D2VL30 | A0A0D2WI06 | Uncharacterized protein. | Origin recognition complex subunit 2. | 0.997 |
CAOG_002048 | CAOG_005056 | A0A0D2VL30 | A0A0D2WSH5 | Uncharacterized protein. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.994 |
CAOG_002048 | CAOG_005062 | A0A0D2VL30 | A0A0D2X3J5 | Uncharacterized protein. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.998 |
CAOG_002048 | CAOG_007159 | A0A0D2VL30 | A0A0D2UPG4 | Uncharacterized protein. | Origin recognition complex ORC subunit 3. | 0.998 |
CAOG_002048 | CAOG_008193 | A0A0D2VL30 | A0A0D2UT94 | Uncharacterized protein. | Origin recognition complex. | 0.997 |
CAOG_004675 | CAOG_005056 | A0A0D2UFQ5 | A0A0D2WSH5 | Importin N-terminal domain-containing protein. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.638 |
CAOG_005056 | CAOG_000143 | A0A0D2WSH5 | A0A0D2WI06 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | Origin recognition complex subunit 2. | 0.997 |