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hisG hisG hisD hisD hisI hisI EFL51525.1 EFL51525.1 hisC-2 hisC-2 hisA hisA hisC hisC hisF hisF hisB hisB EFL50826.1 EFL50826.1 EFL50827.1 EFL50827.1 hisH-2 hisH-2 EFL50838.1 EFL50838.1 hisH-3 hisH-3 EFL50757.1 EFL50757.1 hisH hisH EFL52075.1 EFL52075.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (293 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (436 aa)
hisIPhosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (124 aa)
EFL51525.1TIGRFAM: imidazolonepropionase; KEGG: gtn:GTNG_1226 imidazolonepropionase; PFAM: amidohydrolase; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (417 aa)
hisC-2KEGG: dma:DMR_39240 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (369 aa)
hisATIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; KEGG: dma:DMR_22350 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino] imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis protein. (247 aa)
hisCPFAM: aminotransferase class I and II; KEGG: dma:DMR_19340 aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (369 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (259 aa)
hisBKEGG: dma:DMR_22370 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase. (196 aa)
EFL50826.1TIGRFAM: N-acetyl sugar amidotransferase; KEGG: lpf:lpl0785 hypothetical protein. (440 aa)
EFL50827.1Glycosyl amidation-associated protein WbuZ; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
hisH-2Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (214 aa)
EFL50838.1Histidine biosynthesis protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (254 aa)
hisH-3Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (205 aa)
EFL50757.1KEGG: dde:Dde_2849 ISPg7, transposase. (121 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (209 aa)
EFL52075.1KEGG: dma:DMR_17210 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein. (221 aa)
Your Current Organism:
Desulfovibrio fructosivorans
NCBI taxonomy Id: 596151
Other names: D. fructosivorans JJ, Desulfovibrio fructosivorans ATCC 49200, Desulfovibrio fructosivorans DSM 3604, Desulfovibrio fructosivorans JJ, Desulfovibrio fructosivorans str. JJ, Desulfovibrio fructosivorans strain JJ, Desulfovibrio fructosovorans JJ
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