node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EIG53656.1 | EIG53659.1 | DesU5LDRAFT_1983 | DesU5LDRAFT_1986 | Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. | Flagellar GTP-binding protein; PFAM: SRP54-type protein, GTPase domain. | 0.943 |
EIG53659.1 | EIG53656.1 | DesU5LDRAFT_1986 | DesU5LDRAFT_1983 | Flagellar GTP-binding protein; PFAM: SRP54-type protein, GTPase domain. | Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. | 0.943 |
EIG54442.1 | EIG55372.1 | DesU5LDRAFT_2797 | DesU5LDRAFT_3755 | Hypothetical protein; PFAM: SEC-C motif; Belongs to the UPF0225 family. | PFAM: Plasmid pRiA4b ORF-3-like protein; manually curated. | 0.433 |
EIG54442.1 | ffh | DesU5LDRAFT_2797 | DesU5LDRAFT_2824 | Hypothetical protein; PFAM: SEC-C motif; Belongs to the UPF0225 family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.636 |
EIG54442.1 | secA | DesU5LDRAFT_2797 | DesU5LDRAFT_2923 | Hypothetical protein; PFAM: SEC-C motif; Belongs to the UPF0225 family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.460 |
EIG54442.1 | secD | DesU5LDRAFT_2797 | DesU5LDRAFT_1649 | Hypothetical protein; PFAM: SEC-C motif; Belongs to the UPF0225 family. | Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.638 |
EIG54442.1 | secF | DesU5LDRAFT_2797 | DesU5LDRAFT_1067 | Hypothetical protein; PFAM: SEC-C motif; Belongs to the UPF0225 family. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.563 |
EIG54442.1 | secY | DesU5LDRAFT_2797 | DesU5LDRAFT_3599 | Hypothetical protein; PFAM: SEC-C motif; Belongs to the UPF0225 family. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.694 |
EIG54993.1 | EIG55372.1 | DesU5LDRAFT_3363 | DesU5LDRAFT_3755 | Hypothetical protein. | PFAM: Plasmid pRiA4b ORF-3-like protein; manually curated. | 0.665 |
EIG54993.1 | ffh | DesU5LDRAFT_3363 | DesU5LDRAFT_2824 | Hypothetical protein. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.689 |
EIG54993.1 | ftsY | DesU5LDRAFT_3363 | DesU5LDRAFT_1713 | Hypothetical protein. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.698 |
EIG54993.1 | secA | DesU5LDRAFT_3363 | DesU5LDRAFT_2923 | Hypothetical protein. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.665 |
EIG54993.1 | secD | DesU5LDRAFT_3363 | DesU5LDRAFT_1649 | Hypothetical protein. | Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.707 |
EIG54993.1 | secE | DesU5LDRAFT_3363 | DesU5LDRAFT_2427 | Hypothetical protein. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.711 |
EIG54993.1 | secF | DesU5LDRAFT_3363 | DesU5LDRAFT_1067 | Hypothetical protein. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.702 |
EIG54993.1 | secY | DesU5LDRAFT_3363 | DesU5LDRAFT_3599 | Hypothetical protein. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.702 |
EIG55372.1 | EIG54442.1 | DesU5LDRAFT_3755 | DesU5LDRAFT_2797 | PFAM: Plasmid pRiA4b ORF-3-like protein; manually curated. | Hypothetical protein; PFAM: SEC-C motif; Belongs to the UPF0225 family. | 0.433 |
EIG55372.1 | EIG54993.1 | DesU5LDRAFT_3755 | DesU5LDRAFT_3363 | PFAM: Plasmid pRiA4b ORF-3-like protein; manually curated. | Hypothetical protein. | 0.665 |
EIG55372.1 | ffh | DesU5LDRAFT_3755 | DesU5LDRAFT_2824 | PFAM: Plasmid pRiA4b ORF-3-like protein; manually curated. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.674 |
EIG55372.1 | ftsY | DesU5LDRAFT_3755 | DesU5LDRAFT_1713 | PFAM: Plasmid pRiA4b ORF-3-like protein; manually curated. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.660 |