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| | EIG52978.1 | Hypothetical protein; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179). (283 aa) |
| | EIG52917.1 | Putative Rossmann fold nucleotide-binding protein. (755 aa) |
| | EIG52915.1 | Adenylylsulfate kinase ApsK; PFAM: ATP-sulfurylase; Adenylylsulphate kinase. (567 aa) |
| | EIG52868.1 | PFAM: Bacterial DNA-binding protein; Belongs to the bacterial histone-like protein family. (91 aa) |
| | surE | 5''/3''-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (255 aa) |
| | EIG52838.1 | CBS domain-containing protein; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain. (437 aa) |
| | EIG52821.1 | MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain. (261 aa) |
| | EIG51943.1 | Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; [2Fe-2S] binding domain. (947 aa) |
| | EIG51955.1 | Electron transfer flavoprotein, beta subunit; PFAM: Electron transfer flavoprotein domain. (266 aa) |
| | EIG52055.1 | PFAM: Amino acid kinase family; Belongs to the carbamate kinase family. (314 aa) |
| | EIG52060.1 | AIR synthase-related protein, sll0787 family; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain. (322 aa) |
| | EIG52161.1 | PFAM: Lyase; Adenylosuccinate lyase C-terminus; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (437 aa) |
| | EIG52195.1 | Bacterial nucleoid DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (100 aa) |
| | EIG52196.1 | HIT family hydrolase, diadenosine tetraphosphate hydrolase; PFAM: HIT domain. (142 aa) |
| | EIG52213.1 | CBS-domain-containing membrane protein; PFAM: CBS domain. (129 aa) |
| | EIG52234.1 | Ribonucleotide reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (1115 aa) |
| | EIG52242.1 | Anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP cone domain. (682 aa) |
| | EIG52272.1 | AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain. (197 aa) |
| | EIG52319.1 | Hypothetical protein. (159 aa) |
| | EIG52339.1 | Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; [2Fe-2S] binding domain. (909 aa) |
| | ychF | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (368 aa) |
| | EIG52462.1 | Anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP cone domain. (728 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (226 aa) |
| | EIG52546.1 | Hypothetical protein; PFAM: S-adenosyl-l-methionine hydroxide adenosyltransferase. (262 aa) |
| | truA | Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (270 aa) |
| | EIG52765.1 | Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I. (457 aa) |
| | EIG52617.1 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (467 aa) |
| | EIG54588.1 | Hypothetical protein. (554 aa) |
| | EIG54546.1 | GMP synthase family protein; PFAM: Glutamine amidotransferase class-I. (234 aa) |
| | EIG54518.1 | PFAM: ATP-sulfurylase; TIGRFAM: ATP sulphurylase. (430 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, PurE protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | purD | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. (426 aa) |
| | EIG54295.1 | Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM-like protein; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain. (336 aa) |
| | EIG54294.1 | Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain. (835 aa) |
| | EIG54293.1 | Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS-like protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain. (210 aa) |
| | EIG54239.1 | Putative permease; PFAM: Domain of unknown function DUF20. (404 aa) |
| | EIG54194.1 | PFAM: Domain of unknown function (DUF3473); Polysaccharide deacetylase; TIGRFAM: polysaccharide deacetylase family protein, PEP-CTERM locus subfamily. (303 aa) |
| | EIG54152.1 | Adenylate cyclase, class 2 (thermophilic); PFAM: CYTH domain; TIGRFAM: adenylyl cyclase CyaB, putative. (182 aa) |
| | EIG54014.1 | Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; 2Fe-2S iron-sulfur cluster binding domain; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; [2Fe-2S] binding domain. (914 aa) |
| | EIG53931.1 | Hypothetical protein. (236 aa) |
| | EIG53929.1 | Hypothetical protein. (288 aa) |
| | EIG53928.1 | PFAM: Bacterial DNA-binding protein; Belongs to the bacterial histone-like protein family. (91 aa) |
| | EIG53923.1 | CBS domain-containing protein; PFAM: CBS domain; Transporter associated domain. (271 aa) |
| | EIG53417.1 | Adenylate cyclase, class 2 (thermophilic); PFAM: CYTH domain. (199 aa) |
| | EIG55683.1 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (209 aa) |
| | EIG55655.1 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. (538 aa) |
| | EIG55630.1 | Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; [2Fe-2S] binding domain. (915 aa) |
| | EIG55603.1 | Putative phosphatase, C-terminal domain of histone macro H2A1 like protein; PFAM: Macro domain. (184 aa) |
| | EIG55578.1 | PFAM: Calcineurin-like phosphoesterase. (239 aa) |
| | EIG55527.1 | Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL-like protein; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain. (761 aa) |
| | EIG55525.1 | Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM-like protein; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain. (276 aa) |
| | EIG55520.1 | PFAM: Histidine kinase; 7TM diverse intracellular signalling; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (635 aa) |
| | EIG55366.1 | Hypothetical protein. (297 aa) |
| | EIG55336.1 | (p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (737 aa) |
| | EIG55196.1 | Inosine guanosine and xanthosine phosphorylase family protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (300 aa) |
| | EIG55104.1 | PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain. (744 aa) |
| | EIG55088.1 | Putative ATPase of the PP-loop superfamily implicated in cell cycle control; PFAM: PP-loop family; TIGRFAM: TIGR00269 family protein; Belongs to the TtcA family. (312 aa) |
| | adk | tRNA(Ile)-lysidine synthetase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the tRNA(Ile)-lysidine synthase family. (605 aa) |
| | EIG54984.1 | Putative transmembrane sensor domain protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain. (674 aa) |
| | EIG54981.1 | Putative permease; PFAM: Domain of unknown function DUF20. (346 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase. (353 aa) |
| | EIG54907.1 | CBS domain-containing protein; PFAM: CBS domain. (158 aa) |
| | EIG54880.1 | Putative permease; PFAM: Domain of unknown function DUF20. (370 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (209 aa) |
| | EIG54799.1 | CBS-domain-containing membrane protein; PFAM: CBS domain. (218 aa) |
| | EIG54739.1 | Hypothetical protein. (438 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (393 aa) |
| | EIG54623.1 | Hypothetical protein. (167 aa) |
| | purL | Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...] (998 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (471 aa) |
| | EIG53328.1 | Micrococcal nuclease-like nuclease; PFAM: Staphylococcal nuclease homologue; manually curated. (254 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (516 aa) |
| | guaB | Inosine-5''-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa) |
| | EIG53308.1 | CBS domain-containing protein; PFAM: CBS domain; Domain of unknown function DUF21. (356 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (314 aa) |
| | EIG53267.1 | Adenylylsulfate kinase-like kinase; PFAM: Adenylylsulphate kinase. (192 aa) |
| | EIG53248.1 | PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain. (614 aa) |
| | EIG53218.1 | Hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (172 aa) |
| | EIG53201.1 | Hypothetical protein. (219 aa) |
| | EIG53180.1 | Hypothetical protein. (65 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (138 aa) |
| | EIG51908.1 | PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; Belongs to the pyruvate kinase family. (475 aa) |
| | EIG51879.1 | PFAM: MgtE intracellular N domain; CBS domain. (419 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (438 aa) |
| | EIG51841.1 | AICAR transformylase/IMP cyclohydrolase PurH; PFAM: AICARFT/IMPCHase bienzyme. (425 aa) |
| | EIG52988.1 | Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase. (310 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (171 aa) |
| | EIG53746.1 | Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain. (270 aa) |
| | EIG53730.1 | Bacterial nucleoid DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa) |
| | EIG53694.1 | Putative phosphoesterase, ICC. (222 aa) |
| | EIG53685.1 | LysM domain-containing protein; PFAM: LysM domain. (207 aa) |
| | EIG53677.1 | HIT family hydrolase, diadenosine tetraphosphate hydrolase; PFAM: Protein similar to CwfJ C-terminus 1. (166 aa) |
| | EIG53676.1 | TIGR00725 family protein; PFAM: Possible lysine decarboxylase; TIGRFAM: TIGR00725 family protein. (161 aa) |
| | EIG53654.1 | Putative ATPase of the PP-loop superfamily implicated in cell cycle control; PFAM: PP-loop family; Belongs to the TtcA family. (255 aa) |
| | EIG53634.1 | Phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific. (550 aa) |
| | EIG53422.1 | TIGR00730 family protein; PFAM: Possible lysine decarboxylase; Belongs to the LOG family. (194 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (297 aa) |
| | EIG53472.1 | tRNA nucleotidyltransferase/poly(A) polymerase; PFAM: DHH family; DHHA1 domain; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (947 aa) |
| | ade | Adenine deaminase; PFAM: Amidohydrolase family; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (575 aa) |
| | EIG53504.1 | TIGR00730 family protein; PFAM: Possible lysine decarboxylase; Belongs to the LOG family. (218 aa) |
| | EIG53539.1 | CBS domain-containing protein; PFAM: CBS domain. (154 aa) |
