STRINGSTRING
EIG52711.1 EIG52711.1 secF secF EIG52609.1 EIG52609.1 EIG52608.1 EIG52608.1 tatA tatA EIG52518.1 EIG52518.1 EIG52099.1 EIG52099.1 EIG52095.1 EIG52095.1 EIG52048.1 EIG52048.1 EIG55804.1 EIG55804.1 EIG55701.1 EIG55701.1 tatA-4 tatA-4 EIG55372.1 EIG55372.1 secY secY EIG55112.1 EIG55112.1 EIG55096.1 EIG55096.1 EIG54993.1 EIG54993.1 clpB clpB tatC tatC EIG54773.1 EIG54773.1 EIG54770.1 EIG54770.1 EIG54768.1 EIG54768.1 EIG54767.1 EIG54767.1 EIG54762.1 EIG54762.1 EIG54761.1 EIG54761.1 EIG54760.1 EIG54760.1 EIG54757.1 EIG54757.1 secA secA EIG54525.1 EIG54525.1 EIG54498.1 EIG54498.1 ffh ffh EIG54442.1 EIG54442.1 secE secE EIG53608.1 EIG53608.1 EIG53534.1 EIG53534.1 tatA-3 tatA-3 EIG53419.1 EIG53419.1 ftsY ftsY secD secD yajC yajC tatA-2 tatA-2 EIG53081.1 EIG53081.1 yidC yidC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIG52711.1Soluble lytic murein transglycosylase-like protein; PFAM: Transglycosylase SLT domain. (260 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (363 aa)
EIG52609.1Hypothetical protein. (498 aa)
EIG52608.1GSPII_E-like protein; PFAM: GSPII_E N-terminal domain; Domain of unknown function DUF. (351 aa)
tatATwin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (72 aa)
EIG52518.1Hypothetical protein. (290 aa)
EIG52099.1Type IV secretory pathway, VirD4 component; PFAM: TraG/TraD family. (670 aa)
EIG52095.1Soluble lytic murein transglycosylase-like protein; PFAM: Transglycosylase SLT domain. (214 aa)
EIG52048.1PFAM: Protein phosphatase 2C. (237 aa)
EIG55804.1PFAM: HlyD family secretion protein. (461 aa)
EIG55701.1PFAM: Outer membrane efflux protein. (549 aa)
tatA-4Twin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (89 aa)
EIG55372.1PFAM: Plasmid pRiA4b ORF-3-like protein; manually curated. (190 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (437 aa)
EIG55112.1Flp pilus assembly protein, protease CpaA; PFAM: Type IV leader peptidase family. (165 aa)
EIG55096.1Prepilin signal peptidase PulO-like peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (263 aa)
EIG54993.1Hypothetical protein. (226 aa)
clpBATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (866 aa)
tatCTwin arginine targeting protein translocase subunit TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (364 aa)
EIG54773.1PFAM: Competence protein A. (690 aa)
EIG54770.1Type II secretory pathway, component PulD; PFAM: Secretin and TonB N terminus short domain; Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein. (629 aa)
EIG54768.1Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; PFAM: GSPII_E N-terminal domain; Type II/IV secretion system protein. (569 aa)
EIG54767.1Type II secretory pathway, component PulF; PFAM: Bacterial type II secretion system protein F domain. (408 aa)
EIG54762.1TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; overlaps another CDS with the same product name. (172 aa)
EIG54761.1PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; overlaps another CDS with the same product name. (153 aa)
EIG54760.1PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain. (179 aa)
EIG54757.1Soluble lytic murein transglycosylase-like protein; PFAM: Transglycosylase SLT domain. (185 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (837 aa)
EIG54525.1PFAM: Protein kinase domain; Protein of unknown function (DUF1566). (448 aa)
EIG54498.1Soluble lytic murein transglycosylase-like protein; PFAM: Transglycosylase SLT domain. (231 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] (499 aa)
EIG54442.1Hypothetical protein; PFAM: SEC-C motif; Belongs to the UPF0225 family. (174 aa)
secEPreprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (103 aa)
EIG53608.1Transglycosylase family protein; PFAM: Transglycosylase SLT domain. (188 aa)
EIG53534.1Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (110 aa)
tatA-3Twin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (65 aa)
EIG53419.1ATP-dependent Clp protease ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); Belongs to the ClpA/ClpB family. (762 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (593 aa)
secDProtein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (534 aa)
yajCPreprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (125 aa)
tatA-2Twin arginine-targeting protein translocase TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Belongs to the TatA/E family. (159 aa)
EIG53081.1Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (133 aa)
yidCMembrane protein insertase, YidC/Oxa1 family, N-terminal domain; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (530 aa)
Your Current Organism:
Desulfovibrio sp. U5L
NCBI taxonomy Id: 596152
Other names: D. sp. U5L
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