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| | hutU-4 | Urocanate hydratase; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. (88 aa) |
| | hutU-3 | Urocanate hydratase; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. (123 aa) |
| | hutU-2 | Urocanate hydratase; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. (121 aa) |
| | EEK17483.1 | Hypothetical protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. (33 aa) |
| | EEK17258.1 | Hypothetical protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. (43 aa) |
| | pheS | phenylalanine--tRNA ligase, alpha subunit; Identified by match to protein family HMM PF01409; match to protein family HMM PF02912; match to protein family HMM TIGR00468; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (341 aa) |
| | fadD | AMP-binding enzyme; Identified by match to protein family HMM PF00501. (603 aa) |
| | hemD | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (251 aa) |
| | ilvE | Branched-chain-amino-acid transaminase; Identified by match to protein family HMM PF01063; match to protein family HMM TIGR01123. (339 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (441 aa) |
| | mdh | Lactate/malate dehydrogenase, NAD binding domain protein; Identified by match to protein family HMM PF00056; match to protein family HMM PF02866; Belongs to the LDH/MDH superfamily. (332 aa) |
| | argS | arginine--tRNA ligase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. (604 aa) |
| | EEK16464.1 | Hypothetical protein. (391 aa) |
| | pyrB | Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (305 aa) |
| | folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (124 aa) |
| | kbl | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (396 aa) |
| | EEK17479.1 | Hypothetical protein. (185 aa) |
| | EEK17457.1 | Putative 3-deoxy-7-phosphoheptulonate synthase; Identified by match to protein family HMM PF00793; match to protein family HMM PF01817. (365 aa) |
| | EEK17476.1 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase. (126 aa) |
| | hbd | 3-hydroxybutyryl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737. (313 aa) |
| | EEK16157.1 | Amidohydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891. (383 aa) |
| | ispE | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (281 aa) |
| | megL | Methionine gamma-lyase; Identified by match to protein family HMM PF00266; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01328. (400 aa) |
| | metG | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (683 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (115 aa) |
| | aroE | Putative shikimate dehydrogenase; Identified by match to protein family HMM PF01488; match to protein family HMM PF08501. (250 aa) |
| | EEK17690.1 | 3-hydroxybutyryl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737. (282 aa) |
| | EEK17700.1 | Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa) |
| | EEK17729.1 | D-Lysine 5,6-aminomutase alpha subunit; Identified by match to protein family HMM PF09043. (523 aa) |
| | ablA | Lysine-2,3-aminomutase; Identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238. (421 aa) |
| | EEK17722.1 | Oxidoreductase, zinc-binding dehydrogenase family protein; Identified by match to protein family HMM PF00107. (347 aa) |
| | EEK17708.1 | Identified by match to protein family HMM PF05853. (275 aa) |
| | EEK17699.1 | beta-alanyl-CoA:ammonia lyase. (130 aa) |
| | hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (664 aa) |
| | proS | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (494 aa) |
| | mmdC | Biotin-requiring enzyme; Identified by match to protein family HMM PF00364. (145 aa) |
| | EEK16127.1 | Carboxyl transferase domain protein; Identified by match to protein family HMM PF01039. (517 aa) |
| | mce | methylmalonyl-CoA epimerase; Identified by match to protein family HMM PF00903; match to protein family HMM TIGR03081. (138 aa) |
| | gcvP | Glycine dehydrogenase; Identified by match to protein family HMM PF02347; match to protein family HMM TIGR00461; Belongs to the GcvP family. (961 aa) |
| | EEK16118.1 | Metallo-beta-lactamase domain protein; Identified by match to protein family HMM PF00753. (217 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (283 aa) |
| | EEK16105.1 | AMP-binding enzyme; Identified by match to protein family HMM PF00501. (568 aa) |
| | fabF | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (417 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (79 aa) |
| | leuS | leucine--tRNA ligase; Identified by match to protein family HMM PF08264; match to protein family HMM PF09334; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. (938 aa) |
| | algI | Identified by match to protein family HMM PF03062; Belongs to the membrane-bound acyltransferase family. (508 aa) |
| | trpS | tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (331 aa) |
| | abfD | Gamma-aminobutyrate metabolism dehydratase/isomerase; Identified by match to protein family HMM PF03241. (491 aa) |
| | cat-2 | 4-hydroxybutyrate coenzyme A transferase; Identified by match to protein family HMM PF02550. (428 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (150 aa) |
| | glyS | glycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (517 aa) |
| | mutA | methylmalonyl-CoA mutase, small subunit; Identified by match to protein family HMM PF01642; match to protein family HMM TIGR00642. (623 aa) |
| | aspS | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (580 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (336 aa) |
| | bioA | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (437 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (362 aa) |
| | tyrS | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (436 aa) |
| | folD | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (297 aa) |
| | coaBC | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (409 aa) |
| | carA | Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. (368 aa) |
| | EEK16441.1 | Class II glutamine amidotransferase; Identified by match to protein family HMM PF00310. (634 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (533 aa) |
| | serB | Phosphoserine phosphatase SerB; Identified by match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM PF08282; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488. (429 aa) |
| | EEK17151.1 | Putative arginine decarboxylase, pyruvoyl-dependent. (184 aa) |
| | EEK17126.1 | Methylaspartate ammonia-lyase; Identified by match to protein family HMM PF05034; match to protein family HMM PF07476; match to protein family HMM TIGR01502. (414 aa) |
| | glmE | Methylaspartate mutase, E subunit; Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate). (482 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (327 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (224 aa) |
| | gltX | glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (527 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (286 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa) |
| | gcvT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (363 aa) |
| | EEK16045.1 | Putative phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769. (1233 aa) |
| | EEK16175.1 | Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. (302 aa) |
| | nagB | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (268 aa) |
| | aroQ | Dehydroquinase class II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (159 aa) |
| | lysC | Amino acid kinase family; Identified by match to protein family HMM PF00696; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. (458 aa) |
| | sufS | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (408 aa) |
| | fabH | 3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (340 aa) |
| | ispD | Putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Identified by match to protein family HMM PF01128. (250 aa) |
| | fda | Fructose-1,6-bisphosphate aldolase; Identified by match to protein family HMM PF00274; Belongs to the class I fructose-bisphosphate aldolase family. (293 aa) |
| | glnS | glutamine--tRNA ligase; Identified by match to protein family HMM PF00749; match to protein family HMM PF03950; match to protein family HMM TIGR00440. (565 aa) |
| | valS | valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (887 aa) |
| | maeB | Malate dehydrogenase (oxaloacetate-decarboxylating); Identified by match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. (758 aa) |
| | EEK16971.1 | Peptidase dimerization domain protein; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687. (452 aa) |
| | EEK16871.1 | L-asparaginase, type I; Identified by match to protein family HMM PF00710; match to protein family HMM TIGR00519. (351 aa) |
| | EEK16865.1 | Metallo-beta-lactamase domain protein; Identified by match to protein family HMM PF00753. (269 aa) |
| | hisS | histidine--tRNA ligase; Identified by match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442. (459 aa) |
| | folA | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (173 aa) |
| | hydE | Iron-only hydrogenase maturation rSAM protein HydE; Identified by match to protein family HMM PF04055. (349 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (310 aa) |
| | serS | serine--tRNA ligase; Identified by match to protein family HMM PF00587; match to protein family HMM PF02403; match to protein family HMM TIGR00414. (424 aa) |
| | ppdK | Pyruvate, phosphate dikinase; Identified by match to protein family HMM PF00391; match to protein family HMM PF01326; match to protein family HMM PF02896; match to protein family HMM TIGR01828; Belongs to the PEP-utilizing enzyme family. (909 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (178 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa) |
| | EEK16930.1 | Putative o-succinylbenzoate synthase; Identified by match to protein family HMM PF01188. (368 aa) |
| | EEK16889.1 | Bacterial transferase hexapeptide repeat protein; Identified by match to protein family HMM PF00132. (152 aa) |
| | EEK16905.1 | Putative arginase; Identified by match to protein family HMM PF00491; Belongs to the arginase family. (298 aa) |
| | EEK16901.1 | Nucleotide sugar dehydrogenase; Identified by match to protein family HMM PF00984; match to protein family HMM PF01210; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026. (440 aa) |
| | thrS | threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (650 aa) |
| | EEK17808.1 | Hypothetical protein. (201 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (255 aa) |
| | gltA | Glutamate synthase (NADPH), homotetrameric; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01316. (491 aa) |
| | pgk | Phosphoglycerate kinase; Identified by match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (423 aa) |
| | gdh | Glutamate dehydrogenase, NAD-specific; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (445 aa) |
| | cat | 4-hydroxybutyrate coenzyme A transferase; Identified by match to protein family HMM PF02550. (436 aa) |
| | ugd | Nucleotide sugar dehydrogenase; Identified by match to protein family HMM PF00984; match to protein family HMM PF01210; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026. (412 aa) |
| | hutH | Histidine ammonia-lyase; Identified by match to protein family HMM PF00221; match to protein family HMM TIGR01225. (499 aa) |
| | hutI | Imidazolonepropionase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01224; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (424 aa) |
| | ftcD | Glutamate formimidoyltransferase; Identified by match to protein family HMM PF02971; match to protein family HMM PF07837; match to protein family HMM TIGR02024. (301 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (843 aa) |
| | panE | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (320 aa) |
| | gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa) |
| | cysS | cysteine--tRNA ligase; Identified by match to protein family HMM PF01406; match to protein family HMM PF09190; match to protein family HMM PF09334; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family. (492 aa) |
| | EEK16413.1 | Radical SAM domain protein; Identified by match to protein family HMM PF04055. (379 aa) |
| | fabD | [acyl-carrier-protein] S-malonyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128. (292 aa) |
| | fabG | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. (155 aa) |
| | ileS | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1137 aa) |
| | alaS | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (872 aa) |
| | EEK16385.1 | Putative 3-dehydroquinate synthase; Identified by match to protein family HMM PF01761. (364 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (273 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. (506 aa) |
| | cobB | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (433 aa) |
| | lysS | lysine--tRNA ligase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family. (579 aa) |
| | pgi | Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00342; Belongs to the GPI family. (455 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (381 aa) |
| | EEK15995.1 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (428 aa) |
| | serC | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (360 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (314 aa) |
| | EEK17596.1 | Succinate CoA transferase; Identified by match to protein family HMM PF02550; match to protein family HMM TIGR03458. (493 aa) |
| | cobQ | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (499 aa) |
| | fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (460 aa) |
| | EEK17582.1 | Beta-eliminating lyase; Identified by match to protein family HMM PF01212. (459 aa) |
| | EEK16989.1 | Hypothetical protein. (281 aa) |
| | mtnN | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (250 aa) |
| | pheT | phenylalanine--tRNA ligase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (829 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (158 aa) |
| | EEK17017.1 | LytB protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (306 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (596 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa) |
| | argR | Arginine repressor, C-terminal domain protein; Regulates arginine biosynthesis genes. (169 aa) |
| | EEK17395.1 | Identified by match to protein family HMM PF06354; Belongs to the UPF0597 family. (437 aa) |
| | asnS | asparagine--tRNA ligase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. (471 aa) |
| | hutU-5 | Urocanate hydratase; This gene contains a nucleotide ambiguity which may be the result of a sequencing error. (70 aa) |
