(33 nodes) Mixed, incl. MAP kinase activity, and Mitogen-activated protein (MAP) kinase phosphatase network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAP3K1	Mitogen-activated protein kinase kinase kinase 1. (1654 aa)
	MAPK12	Mitogen-activated protein kinase. (361 aa)
	MAPK11	Mitogen-activated protein kinase. (361 aa)
	HSPB1	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (191 aa)
	MAP2K4	Mitogen-activated protein kinase kinase 4. (483 aa)
	DUSP7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
	MAPKAPK5	MAPK activated protein kinase 5. (471 aa)
	PTPRR	Protein tyrosine phosphatase receptor type R. (659 aa)
	MAP2K3	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (383 aa)
	DUSP6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
	MAPK8	Mitogen-activated protein kinase. (401 aa)
	PTPN5	Uncharacterized protein. (560 aa)
	DUSP8	Dual specificity phosphatase 8. (635 aa)
	MAPK8IP1	Mitogen-activated protein kinase 8 interacting protein 1. (699 aa)
	DUSP16	Dual specificity phosphatase 16. (657 aa)
	MAPK10	Mitogen-activated protein kinase. (472 aa)
	ENSTGUP00000019325	Uncharacterized protein LOC115492334. (450 aa)
	ENSTGUP00000020712	annotation not available (97 aa)
	LRP8	LDL receptor related protein 8. (964 aa)
	ENSTGUP00000023897	annotation not available (462 aa)
	PEA15	Proliferation and apoptosis adaptor protein 15. (130 aa)
	DUSP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
	LOC115492829	Mitogen-activated protein kinase 7-like. (819 aa)
	MAPKAPK3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (386 aa)
	MAPKAPK2	Mitogen-activated protein kinase-activated protein kinase 2. (525 aa)
	MAPK8IP3	Mitogen-activated protein kinase 8 interacting protein 3. (1350 aa)
	ENSTGUP00000031367	annotation not available (619 aa)
	MAPK1	Mitogen-activated protein kinase. (369 aa)
	LOC115492581	Mitogen-activated protein kinase 8 interacting protein 2. (1134 aa)
	MAP3K20	Mitogen-activated protein kinase kinase kinase 20. (476 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	PTPN7	Protein tyrosine phosphatase non-receptor type 7. (363 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP16	ENSTGUP00000019325	ENSTGUP00000013084	ENSTGUP00000019325	Dual specificity phosphatase 16.	Uncharacterized protein LOC115492334.	0.415
DUSP16	ENSTGUP00000020712	ENSTGUP00000013084	ENSTGUP00000020712	Dual specificity phosphatase 16.	annotation not available	0.521
DUSP16	ENSTGUP00000023897	ENSTGUP00000013084	ENSTGUP00000023897	Dual specificity phosphatase 16.	annotation not available	0.521
DUSP16	ENSTGUP00000031367	ENSTGUP00000013084	ENSTGUP00000031367	Dual specificity phosphatase 16.	annotation not available	0.415
DUSP16	LOC115492829	ENSTGUP00000013084	ENSTGUP00000027246	Dual specificity phosphatase 16.	Mitogen-activated protein kinase 7-like.	0.521
DUSP16	MAPK1	ENSTGUP00000013084	ENSTGUP00000031436	Dual specificity phosphatase 16.	Mitogen-activated protein kinase.	0.950
DUSP16	MAPK10	ENSTGUP00000013084	ENSTGUP00000018345	Dual specificity phosphatase 16.	Mitogen-activated protein kinase.	0.966
DUSP16	MAPK11	ENSTGUP00000013084	ENSTGUP00000004226	Dual specificity phosphatase 16.	Mitogen-activated protein kinase.	0.846
DUSP16	MAPK12	ENSTGUP00000013084	ENSTGUP00000004189	Dual specificity phosphatase 16.	Mitogen-activated protein kinase.	0.846
DUSP16	MAPK14	ENSTGUP00000013084	ENSTGUP00000035748	Dual specificity phosphatase 16.	Mitogen-activated protein kinase.	0.846
DUSP16	MAPK8	ENSTGUP00000013084	ENSTGUP00000008391	Dual specificity phosphatase 16.	Mitogen-activated protein kinase.	0.674
DUSP16	MAPK9	ENSTGUP00000013084	ENSTGUP00000037079	Dual specificity phosphatase 16.	Mitogen-activated protein kinase.	0.959
DUSP3	MAPK1	ENSTGUP00000026722	ENSTGUP00000031436	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.936
DUSP3	MAPK10	ENSTGUP00000026722	ENSTGUP00000018345	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.928
DUSP3	MAPK11	ENSTGUP00000026722	ENSTGUP00000004226	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.930
DUSP3	MAPK12	ENSTGUP00000026722	ENSTGUP00000004189	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.930
DUSP3	MAPK14	ENSTGUP00000026722	ENSTGUP00000035748	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.930
DUSP3	MAPK9	ENSTGUP00000026722	ENSTGUP00000037079	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.929
DUSP3	PTPN5	ENSTGUP00000026722	ENSTGUP00000009271	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Uncharacterized protein.	0.905
DUSP3	PTPN7	ENSTGUP00000026722	ENSTGUP00000037658	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase non-receptor type 7.	0.924