(19 nodes) ERK/MAPK targets, and Protein-tyrosine phosphatase, KIM-containing network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAPK12	Mitogen-activated protein kinase. (361 aa)
	MAPK11	Mitogen-activated protein kinase. (361 aa)
	HSPB1	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (191 aa)
	DUSP7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
	MAPKAPK5	MAPK activated protein kinase 5. (471 aa)
	PTPRR	Protein tyrosine phosphatase receptor type R. (659 aa)
	MAP2K3	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (383 aa)
	DUSP6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
	PTPN5	Uncharacterized protein. (560 aa)
	ENSTGUP00000020712	annotation not available (97 aa)
	ENSTGUP00000023897	annotation not available (462 aa)
	PEA15	Proliferation and apoptosis adaptor protein 15. (130 aa)
	DUSP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
	LOC115492829	Mitogen-activated protein kinase 7-like. (819 aa)
	MAPKAPK3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (386 aa)
	MAPKAPK2	Mitogen-activated protein kinase-activated protein kinase 2. (525 aa)
	MAPK1	Mitogen-activated protein kinase. (369 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	PTPN7	Protein tyrosine phosphatase non-receptor type 7. (363 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP3	MAPK1	ENSTGUP00000026722	ENSTGUP00000031436	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.936
DUSP3	MAPK11	ENSTGUP00000026722	ENSTGUP00000004226	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.930
DUSP3	MAPK12	ENSTGUP00000026722	ENSTGUP00000004189	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.930
DUSP3	MAPK14	ENSTGUP00000026722	ENSTGUP00000035748	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.930
DUSP3	PTPN5	ENSTGUP00000026722	ENSTGUP00000009271	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Uncharacterized protein.	0.905
DUSP3	PTPN7	ENSTGUP00000026722	ENSTGUP00000037658	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase non-receptor type 7.	0.924
DUSP3	PTPRR	ENSTGUP00000026722	ENSTGUP00000007362	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase receptor type R.	0.909
DUSP6	ENSTGUP00000020712	ENSTGUP00000008299	ENSTGUP00000020712	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	annotation not available	0.705
DUSP6	ENSTGUP00000023897	ENSTGUP00000008299	ENSTGUP00000023897	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	annotation not available	0.705
DUSP6	LOC115492829	ENSTGUP00000008299	ENSTGUP00000027246	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase 7-like.	0.705
DUSP6	MAPK1	ENSTGUP00000008299	ENSTGUP00000031436	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.969
DUSP6	MAPK11	ENSTGUP00000008299	ENSTGUP00000004226	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.554
DUSP6	MAPK12	ENSTGUP00000008299	ENSTGUP00000004189	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.554
DUSP6	MAPK14	ENSTGUP00000008299	ENSTGUP00000035748	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.554
DUSP7	ENSTGUP00000020712	ENSTGUP00000006196	ENSTGUP00000020712	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	annotation not available	0.705
DUSP7	ENSTGUP00000023897	ENSTGUP00000006196	ENSTGUP00000023897	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	annotation not available	0.705
DUSP7	LOC115492829	ENSTGUP00000006196	ENSTGUP00000027246	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase 7-like.	0.705
DUSP7	MAPK1	ENSTGUP00000006196	ENSTGUP00000031436	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.969
DUSP7	MAPK11	ENSTGUP00000006196	ENSTGUP00000004226	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.837
DUSP7	MAPK12	ENSTGUP00000006196	ENSTGUP00000004189	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.837