(13 nodes) Mixed, incl. Protein-tyrosine phosphatase, KIM-containing, and Mitogen-activated protein (MAP) kinase p38-like network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAPK12	Mitogen-activated protein kinase. (361 aa)
	MAPK11	Mitogen-activated protein kinase. (361 aa)
	HSPB1	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (191 aa)
	MAPKAPK5	MAPK activated protein kinase 5. (471 aa)
	PTPRR	Protein tyrosine phosphatase receptor type R. (659 aa)
	MAP2K3	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (383 aa)
	PTPN5	Uncharacterized protein. (560 aa)
	DUSP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
	MAPKAPK3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (386 aa)
	MAPKAPK2	Mitogen-activated protein kinase-activated protein kinase 2. (525 aa)
	MAPK1	Mitogen-activated protein kinase. (369 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	PTPN7	Protein tyrosine phosphatase non-receptor type 7. (363 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP3	MAPK1	ENSTGUP00000026722	ENSTGUP00000031436	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.936
DUSP3	MAPK11	ENSTGUP00000026722	ENSTGUP00000004226	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.930
DUSP3	MAPK12	ENSTGUP00000026722	ENSTGUP00000004189	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.930
DUSP3	MAPK14	ENSTGUP00000026722	ENSTGUP00000035748	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.930
DUSP3	PTPN5	ENSTGUP00000026722	ENSTGUP00000009271	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Uncharacterized protein.	0.905
DUSP3	PTPN7	ENSTGUP00000026722	ENSTGUP00000037658	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase non-receptor type 7.	0.924
DUSP3	PTPRR	ENSTGUP00000026722	ENSTGUP00000007362	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein tyrosine phosphatase receptor type R.	0.909
HSPB1	MAPK11	ENSTGUP00000004691	ENSTGUP00000004226	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family.	Mitogen-activated protein kinase.	0.546
HSPB1	MAPK12	ENSTGUP00000004691	ENSTGUP00000004189	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family.	Mitogen-activated protein kinase.	0.489
HSPB1	MAPK14	ENSTGUP00000004691	ENSTGUP00000035748	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family.	Mitogen-activated protein kinase.	0.546
HSPB1	MAPKAPK2	ENSTGUP00000004691	ENSTGUP00000029278	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family.	Mitogen-activated protein kinase-activated protein kinase 2.	0.996
HSPB1	MAPKAPK3	ENSTGUP00000004691	ENSTGUP00000028968	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.989
HSPB1	MAPKAPK5	ENSTGUP00000004691	ENSTGUP00000006822	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family.	MAPK activated protein kinase 5.	0.988
MAP2K3	MAPK1	ENSTGUP00000007758	ENSTGUP00000031436	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.964
MAP2K3	MAPK11	ENSTGUP00000007758	ENSTGUP00000004226	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.983
MAP2K3	MAPK12	ENSTGUP00000007758	ENSTGUP00000004189	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.979
MAP2K3	MAPK14	ENSTGUP00000007758	ENSTGUP00000035748	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.983
MAP2K3	MAPKAPK2	ENSTGUP00000007758	ENSTGUP00000029278	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase-activated protein kinase 2.	0.597
MAP2K3	MAPKAPK3	ENSTGUP00000007758	ENSTGUP00000028968	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.594
MAP2K3	MAPKAPK5	ENSTGUP00000007758	ENSTGUP00000006822	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	MAPK activated protein kinase 5.	0.498