(13 nodes) JNK cascade, and JNK-interacting protein 3/4 network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAP3K1	Mitogen-activated protein kinase kinase kinase 1. (1654 aa)
	MAP2K4	Mitogen-activated protein kinase kinase 4. (483 aa)
	MAPK8	Mitogen-activated protein kinase. (401 aa)
	DUSP8	Dual specificity phosphatase 8. (635 aa)
	MAPK8IP1	Mitogen-activated protein kinase 8 interacting protein 1. (699 aa)
	MAPK10	Mitogen-activated protein kinase. (472 aa)
	ENSTGUP00000019325	Uncharacterized protein LOC115492334. (450 aa)
	LRP8	LDL receptor related protein 8. (964 aa)
	MAPK8IP3	Mitogen-activated protein kinase 8 interacting protein 3. (1350 aa)
	ENSTGUP00000031367	annotation not available (619 aa)
	LOC115492581	Mitogen-activated protein kinase 8 interacting protein 2. (1134 aa)
	MAP3K20	Mitogen-activated protein kinase kinase kinase 20. (476 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP8	ENSTGUP00000019325	ENSTGUP00000009745	ENSTGUP00000019325	Dual specificity phosphatase 8.	Uncharacterized protein LOC115492334.	0.415
DUSP8	ENSTGUP00000031367	ENSTGUP00000009745	ENSTGUP00000031367	Dual specificity phosphatase 8.	annotation not available	0.415
DUSP8	MAPK10	ENSTGUP00000009745	ENSTGUP00000018345	Dual specificity phosphatase 8.	Mitogen-activated protein kinase.	0.966
DUSP8	MAPK8	ENSTGUP00000009745	ENSTGUP00000008391	Dual specificity phosphatase 8.	Mitogen-activated protein kinase.	0.674
DUSP8	MAPK9	ENSTGUP00000009745	ENSTGUP00000037079	Dual specificity phosphatase 8.	Mitogen-activated protein kinase.	0.959
ENSTGUP00000019325	DUSP8	ENSTGUP00000019325	ENSTGUP00000009745	Uncharacterized protein LOC115492334.	Dual specificity phosphatase 8.	0.415
ENSTGUP00000019325	LOC115492581	ENSTGUP00000019325	ENSTGUP00000032671	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase 8 interacting protein 2.	0.523
ENSTGUP00000019325	MAP2K4	ENSTGUP00000019325	ENSTGUP00000006024	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase kinase 4.	0.717
ENSTGUP00000019325	MAP3K1	ENSTGUP00000019325	ENSTGUP00000002666	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase kinase kinase 1.	0.767
ENSTGUP00000019325	MAP3K20	ENSTGUP00000019325	ENSTGUP00000033736	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase kinase kinase 20.	0.676
ENSTGUP00000019325	MAPK10	ENSTGUP00000019325	ENSTGUP00000018345	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase.	0.800
ENSTGUP00000019325	MAPK8	ENSTGUP00000019325	ENSTGUP00000008391	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase.	0.800
ENSTGUP00000019325	MAPK8IP1	ENSTGUP00000019325	ENSTGUP00000011045	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase 8 interacting protein 1.	0.523
ENSTGUP00000019325	MAPK8IP3	ENSTGUP00000019325	ENSTGUP00000030194	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase 8 interacting protein 3.	0.450
ENSTGUP00000019325	MAPK9	ENSTGUP00000019325	ENSTGUP00000037079	Uncharacterized protein LOC115492334.	Mitogen-activated protein kinase.	0.800
ENSTGUP00000031367	DUSP8	ENSTGUP00000031367	ENSTGUP00000009745	annotation not available	Dual specificity phosphatase 8.	0.415
ENSTGUP00000031367	LOC115492581	ENSTGUP00000031367	ENSTGUP00000032671	annotation not available	Mitogen-activated protein kinase 8 interacting protein 2.	0.523
ENSTGUP00000031367	MAP2K4	ENSTGUP00000031367	ENSTGUP00000006024	annotation not available	Mitogen-activated protein kinase kinase 4.	0.709
ENSTGUP00000031367	MAP3K1	ENSTGUP00000031367	ENSTGUP00000002666	annotation not available	Mitogen-activated protein kinase kinase kinase 1.	0.767
ENSTGUP00000031367	MAP3K20	ENSTGUP00000031367	ENSTGUP00000033736	annotation not available	Mitogen-activated protein kinase kinase kinase 20.	0.676