STRINGSTRING
MATK MATK SYK SYK INSR INSR SHC3 SHC3 ITK ITK CSDE1 CSDE1 NRAS NRAS MAP2K2 MAP2K2 RASA1 RASA1 RAPGEF6 RAPGEF6 LCK LCK RAP1A RAP1A LCP2 LCP2 ANKRD50 ANKRD50 SOS1 SOS1 GAB1 GAB1 MARK1 MARK1 PIK3R1 PIK3R1 RGL1 RGL1 RRH RRH DOCK5 DOCK5 PLCG2 PLCG2 MRAS MRAS VAV3 VAV3 PTK7 PTK7 DOCK3 DOCK3 MST1R MST1R YWHAB YWHAB MET MET RIPK4 RIPK4 YWHAE YWHAE MUSTN1 MUSTN1 LRIT1 LRIT1 PTPN11 PTPN11 GRB14 GRB14 LOC100226244 LOC100226244 LPXN LPXN SHC4 SHC4 SRMS SRMS CNKSR2 CNKSR2 SH3KBP1 SH3KBP1 LNX1 LNX1 GRB10 GRB10 H0ZCL7_TAEGU H0ZCL7_TAEGU IRS1 IRS1 LOC100221185 LOC100221185 RASA2 RASA2 RRAS2 RRAS2 CASS4 CASS4 KSR1 KSR1 GRB2 GRB2 IRS2 IRS2 IGF1R IGF1R LOC100227679 LOC100227679 RASGRP3 RASGRP3 INS INS MAP2K1 MAP2K1 HRAS HRAS YES1 YES1 DIRAS1 DIRAS1 HGFAC HGFAC CBY1 CBY1 RAC2 RAC2 PIK3CA PIK3CA HABP2 HABP2 ERBB4 ERBB4 DOCK1 DOCK1 BRAF BRAF SPRED1 SPRED1 YWHAZ YWHAZ COL22A1 COL22A1 KHDRBS2 KHDRBS2 GAB2 GAB2 SOS2 SOS2 CD2AP CD2AP LOC100230753 LOC100230753 H0ZT70_TAEGU H0ZT70_TAEGU TIAM1 TIAM1 CBLB CBLB PTPN1 PTPN1 BTK BTK KHDRBS1 KHDRBS1 INSRR INSRR FRS3 FRS3 SFN SFN NF1 NF1 SHC1 SHC1 YWHAQ YWHAQ RASA3 RASA3 RAPGEF1 RAPGEF1 RAP2C RAP2C STAP2 STAP2 ENSTGUP00000019835 ENSTGUP00000019835 PIK3CD PIK3CD GRAP GRAP PIK3R2 PIK3R2 RAPGEFL1 RAPGEFL1 RAP1A-2 RAP1A-2 LOC100222362 LOC100222362 BLNK BLNK PIK3CB PIK3CB RAP1GAP2 RAP1GAP2 FYN FYN LOC100225168 LOC100225168 FGR FGR PTPN2 PTPN2 RAF1 RAF1 ARL9 ARL9 ENSTGUP00000024560 ENSTGUP00000024560 LYN LYN BCAR1 BCAR1 GRB14-2 GRB14-2 LRIT3 LRIT3 DIRAS3 DIRAS3 RASL11A RASL11A RASGRP1 RASGRP1 RALA RALA TXK TXK LOC100221170 LOC100221170 ENSTGUP00000026788 ENSTGUP00000026788 LOC100220690 LOC100220690 IRS4 IRS4 ENSTGUP00000027661 ENSTGUP00000027661 CRK CRK VAV2 VAV2 CRKL CRKL LOC100228496 LOC100228496 ENSTGUP00000028333 ENSTGUP00000028333 ENSTGUP00000028367 ENSTGUP00000028367 LOC100221871 LOC100221871 RAPGEF2 RAPGEF2 ERBIN ERBIN ELMO2 ELMO2 ENSTGUP00000029388 ENSTGUP00000029388 RALB RALB MARK3 MARK3 YWHAH YWHAH CNKSR3 CNKSR3 PDPK1 PDPK1 ENSTGUP00000030116 ENSTGUP00000030116 RIT1 RIT1 CBL CBL RIT2 RIT2 RALGDS RALGDS RAP1B RAP1B RAP2B RAP2B APBB1IP APBB1IP ENSTGUP00000031187 ENSTGUP00000031187 DOCK2 DOCK2 AKT1 AKT1 CITED2 CITED2 SPRED2 SPRED2 ELMO1 ELMO1 PEBP1 PEBP1 ENSTGUP00000032818 ENSTGUP00000032818 RAPGEF5 RAPGEF5 KSR2 KSR2 DIRAS3-2 DIRAS3-2 SHOC2 SHOC2 ENSTGUP00000034337 ENSTGUP00000034337 LOC100227341 LOC100227341 RAPH1 RAPH1 RALGPS1 RALGPS1 LOC100219956 LOC100219956 LOC100220837 LOC100220837 LOC115494591 LOC115494591 GRAP2 GRAP2 KHDRBS3 KHDRBS3 DOCK4 DOCK4 FRS2 FRS2 ENSTGUP00000037267 ENSTGUP00000037267 RASGEF1C RASGEF1C IPCEF1 IPCEF1 KRAS KRAS YWHAG YWHAG DOCK2-2 DOCK2-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MATKTyrosine-protein kinase. (443 aa)
SYKTyrosine-protein kinase. (668 aa)
INSRInsulin receptor. (1323 aa)
SHC3SHC adaptor protein 3. (632 aa)
ITKTyrosine-protein kinase. (631 aa)
CSDE1Cold shock domain containing E1. (796 aa)
NRASNRAS proto-oncogene, GTPase. (280 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (698 aa)
RASA1RAS p21 protein activator 1. (996 aa)
RAPGEF6Uncharacterized protein. (1468 aa)
LCKProtein kinase domain-containing protein. (513 aa)
RAP1AUncharacterized protein. (184 aa)
LCP2Lymphocyte cytosolic protein 2. (530 aa)
ANKRD50Ankyrin repeat domain 50. (1417 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1322 aa)
GAB1GRB2 associated binding protein 1. (720 aa)
MARK1Non-specific serine/threonine protein kinase. (793 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
RGL1Ral guanine nucleotide dissociation stimulator like 1. (769 aa)
RRHG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (349 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1868 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1223 aa)
MRASMuscle RAS oncogene homolog. (347 aa)
VAV3Vav guanine nucleotide exchange factor 3. (846 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1058 aa)
DOCK3Uncharacterized protein; Belongs to the DOCK family. (1415 aa)
MST1RMacrophage stimulating 1 receptor. (1419 aa)
YWHAB14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (258 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1385 aa)
RIPK4Receptor interacting serine/threonine kinase 4. (789 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (239 aa)
MUSTN1Uncharacterized protein. (78 aa)
LRIT1Leucine rich repeat, Ig-like and transmembrane domains 1. (626 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (582 aa)
GRB14Growth factor receptor bound protein 14. (157 aa)
LOC100226244Uncharacterized protein. (191 aa)
LPXNLeupaxin. (366 aa)
SHC4SHC adaptor protein 4. (634 aa)
SRMSTyrosine-protein kinase. (491 aa)
CNKSR2Uncharacterized protein. (1031 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (704 aa)
LNX1Ligand of numb-protein X 1. (784 aa)
GRB10Growth factor receptor bound protein 10. (596 aa)
H0ZCL7_TAEGUPDZ domain-containing protein. (530 aa)
IRS1Insulin receptor substrate 1. (1233 aa)
LOC100221185Uncharacterized protein. (738 aa)
RASA2Uncharacterized protein. (845 aa)
RRAS2RAS related 2. (203 aa)
CASS4Cas scaffold protein family member 4. (814 aa)
KSR1Kinase suppressor of ras 1. (900 aa)
GRB2Putative growth factor receptor-bound protein 2. (217 aa)
IRS2Insulin receptor substrate 2. (1192 aa)
IGF1RTyrosine-protein kinase receptor. (1363 aa)
LOC100227679Tyrosine-protein phosphatase non-receptor type. (432 aa)
RASGRP3RAS guanyl releasing protein 3. (692 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (137 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (399 aa)
HRASPutative v-Ha-ras Harvey sarcoma viral oncogene variant 2. (189 aa)
YES1Tyrosine-protein kinase. (541 aa)
DIRAS1DIRAS family, GTP-binding Ras-like 1. (196 aa)
HGFACPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (586 aa)
CBY1Chibby family member 1, beta catenin antagonist. (116 aa)
RAC2Rac family small GTPase 2. (206 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
HABP2Uncharacterized protein. (556 aa)
ERBB4Receptor protein-tyrosine kinase. (1244 aa)
DOCK1Uncharacterized protein; Belongs to the DOCK family. (1893 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (765 aa)
SPRED1Sprouty related EVH1 domain containing 1. (413 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
COL22A1Collagen type XXII alpha 1 chain. (1616 aa)
KHDRBS2KH RNA binding domain containing, signal transduction associated 2. (358 aa)
GAB2GRB2 associated binding protein 2. (680 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa)
CD2APCD2 associated protein. (637 aa)
LOC100230753Rap-GAP domain-containing protein. (754 aa)
H0ZT70_TAEGUKIND domain-containing protein. (632 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1604 aa)
CBLBCbl proto-oncogene B. (1025 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type 1. (432 aa)
BTKTyrosine-protein kinase. (662 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (359 aa)
INSRRUncharacterized protein. (1323 aa)
FRS3Fibroblast growth factor receptor substrate 3. (481 aa)
SFNStratifin; Belongs to the 14-3-3 family. (247 aa)
NF1Neurofibromin 1. (2845 aa)
SHC1SHC adaptor protein 1. (609 aa)
YWHAQTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (282 aa)
RASA3RAS p21 protein activator 3. (895 aa)
RAPGEF1Uncharacterized protein. (1232 aa)
RAP2CRAP2C, member of RAS oncogene family. (505 aa)
STAP2Signal-transducing adaptor protein 2 isoform X1. (292 aa)
ENSTGUP00000019835annotation not available (1860 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1054 aa)
GRAPUncharacterized protein. (358 aa)
PIK3R2Uncharacterized protein. (727 aa)
RAPGEFL1Rap guanine nucleotide exchange factor-like 1. (626 aa)
RAP1A-2Ras-related protein Rap-1A. (184 aa)
LOC100222362Phosphoinositide phospholipase C. (1311 aa)
BLNKUncharacterized protein. (601 aa)
PIK3CBUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
RAP1GAP2RAP1 GTPase activating protein 2. (814 aa)
FYNTyrosine-protein kinase. (537 aa)
LOC100225168Tyrosine-protein kinase CSK. (450 aa)
FGRTyrosine-protein kinase. (617 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (420 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (1062 aa)
ARL9ADP ribosylation factor like GTPase 9; Belongs to the small GTPase superfamily. Arf family. (475 aa)
ENSTGUP00000024560annotation not available (98 aa)
LYNTyrosine-protein kinase. (605 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (1231 aa)
GRB14-2Growth factor receptor bound protein 14. (231 aa)
LRIT3Leucine rich repeat, Ig-like and transmembrane domains 3. (636 aa)
DIRAS3Putative Di-Ras2 variant 1. (198 aa)
RASL11ARAS like family 11 member A. (286 aa)
RASGRP1RAS guanyl releasing protein 1. (792 aa)
RALAPutative Ras family small GTP binding protein RALA. (206 aa)
TXKTXK tyrosine kinase. (546 aa)
LOC100221170Uncharacterized protein. (298 aa)
ENSTGUP00000026788MAP/microtubule affinity-regulating kinase 4 isoform X1. (662 aa)
LOC100220690Uncharacterized protein. (231 aa)
IRS4Uncharacterized protein. (1150 aa)
ENSTGUP00000027661annotation not available (73 aa)
CRKUncharacterized protein. (305 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
CRKLUncharacterized protein. (303 aa)
LOC100228496Uncharacterized protein. (250 aa)
ENSTGUP00000028333annotation not available (390 aa)
ENSTGUP00000028367annotation not available (778 aa)
LOC100221871Uncharacterized protein. (355 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1804 aa)
ERBINErbb2 interacting protein. (1482 aa)
ELMO2Engulfment and cell motility 2. (732 aa)
ENSTGUP00000029388annotation not available (1273 aa)
RALBRAS like proto-oncogene B. (273 aa)
MARK3Non-specific serine/threonine protein kinase. (821 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (291 aa)
CNKSR3Uncharacterized protein. (565 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (555 aa)
ENSTGUP00000030116annotation not available (417 aa)
RIT1Ras like without CAAX 1. (215 aa)
CBLUncharacterized protein. (871 aa)
RIT2Ras like without CAAX 2. (217 aa)
RALGDSUncharacterized protein. (830 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
RAP2BRas-related protein Rap-2B. (183 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (778 aa)
ENSTGUP00000031187annotation not available (1080 aa)
DOCK2Dedicator of cytokinesis 2. (923 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (236 aa)
SPRED2Sprouty related EVH1 domain containing 2. (476 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
PEBP1Putative phosphatidylethanolamine-binding protein variant 1. (187 aa)
ENSTGUP00000032818Muscle M-line assembly protein unc-89-like. (2064 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (866 aa)
KSR2Kinase suppressor of ras 2. (972 aa)
DIRAS3-2GTP-binding protein Di-Ras2-like. (198 aa)
SHOC2SHOC2 leucine rich repeat scaffold protein. (582 aa)
ENSTGUP00000034337annotation not available (812 aa)
LOC100227341Uncharacterized protein; Belongs to the DOCK family. (1821 aa)
RAPH1Ras association (RalGDS/AF-6) and pleckstrin homology domains 1. (1278 aa)
RALGPS1Ral GEF with PH domain and SH3 binding motif 1. (586 aa)
LOC100219956Serine/threonine-protein kinase MARK2 isoform X1. (744 aa)
LOC100220837Uncharacterized protein. (1519 aa)
LOC115494591Protein-tyrosine kinase 2-beta. (1047 aa)
GRAP2Uncharacterized protein. (296 aa)
KHDRBS3KH RNA binding domain containing, signal transduction associated 3. (420 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (2086 aa)
FRS2Fibroblast growth factor receptor substrate 2. (529 aa)
ENSTGUP00000037267annotation not available (913 aa)
RASGEF1CRasGEF domain family member 1C. (481 aa)
IPCEF1Interactor protein for cytohesin exchange factors 1 isoform X1. (430 aa)
KRASGTPase KRas. (217 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
DOCK2-2Uncharacterized protein; Belongs to the DOCK family. (1827 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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