STRINGSTRING
MATK MATK SYK SYK INSR INSR SHC3 SHC3 ITK ITK LCK LCK LCP2 LCP2 ANKRD50 ANKRD50 SOS1 SOS1 GAB1 GAB1 PIK3R1 PIK3R1 RRH RRH DOCK5 DOCK5 PLCG2 PLCG2 VAV3 VAV3 PTK7 PTK7 DOCK3 DOCK3 MST1R MST1R MET MET RIPK4 RIPK4 MUSTN1 MUSTN1 LRIT1 LRIT1 PTPN11 PTPN11 LOC100226244 LOC100226244 LPXN LPXN SHC4 SHC4 SRMS SRMS SH3KBP1 SH3KBP1 LNX1 LNX1 GRB10 GRB10 H0ZCL7_TAEGU H0ZCL7_TAEGU IRS1 IRS1 LOC100221185 LOC100221185 CASS4 CASS4 GRB2 GRB2 IRS2 IRS2 IGF1R IGF1R LOC100227679 LOC100227679 INS INS YES1 YES1 HGFAC HGFAC RAC2 RAC2 PIK3CA PIK3CA HABP2 HABP2 ERBB4 ERBB4 DOCK1 DOCK1 COL22A1 COL22A1 KHDRBS2 KHDRBS2 GAB2 GAB2 CD2AP CD2AP H0ZT70_TAEGU H0ZT70_TAEGU TIAM1 TIAM1 CBLB CBLB PTPN1 PTPN1 BTK BTK KHDRBS1 KHDRBS1 INSRR INSRR FRS3 FRS3 SHC1 SHC1 RAPGEF1 RAPGEF1 STAP2 STAP2 ENSTGUP00000019835 ENSTGUP00000019835 PIK3CD PIK3CD GRAP GRAP PIK3R2 PIK3R2 LOC100222362 LOC100222362 BLNK BLNK PIK3CB PIK3CB FYN FYN LOC100225168 LOC100225168 FGR FGR PTPN2 PTPN2 ARL9 ARL9 ENSTGUP00000024560 ENSTGUP00000024560 LYN LYN BCAR1 BCAR1 LRIT3 LRIT3 RASL11A RASL11A TXK TXK LOC100221170 LOC100221170 LOC100220690 LOC100220690 IRS4 IRS4 ENSTGUP00000027661 ENSTGUP00000027661 CRK CRK VAV2 VAV2 CRKL CRKL LOC100228496 LOC100228496 LOC100221871 LOC100221871 ELMO2 ELMO2 PDPK1 PDPK1 CBL CBL DOCK2 DOCK2 AKT1 AKT1 ELMO1 ELMO1 ENSTGUP00000032818 ENSTGUP00000032818 ENSTGUP00000034337 ENSTGUP00000034337 LOC100227341 LOC100227341 RAPH1 RAPH1 RALGPS1 RALGPS1 LOC115494591 LOC115494591 GRAP2 GRAP2 KHDRBS3 KHDRBS3 DOCK4 DOCK4 FRS2 FRS2 RASGEF1C RASGEF1C DOCK2-2 DOCK2-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MATKTyrosine-protein kinase. (443 aa)
SYKTyrosine-protein kinase. (668 aa)
INSRInsulin receptor. (1323 aa)
SHC3SHC adaptor protein 3. (632 aa)
ITKTyrosine-protein kinase. (631 aa)
LCKProtein kinase domain-containing protein. (513 aa)
LCP2Lymphocyte cytosolic protein 2. (530 aa)
ANKRD50Ankyrin repeat domain 50. (1417 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1322 aa)
GAB1GRB2 associated binding protein 1. (720 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
RRHG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (349 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1868 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1223 aa)
VAV3Vav guanine nucleotide exchange factor 3. (846 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1058 aa)
DOCK3Uncharacterized protein; Belongs to the DOCK family. (1415 aa)
MST1RMacrophage stimulating 1 receptor. (1419 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1385 aa)
RIPK4Receptor interacting serine/threonine kinase 4. (789 aa)
MUSTN1Uncharacterized protein. (78 aa)
LRIT1Leucine rich repeat, Ig-like and transmembrane domains 1. (626 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (582 aa)
LOC100226244Uncharacterized protein. (191 aa)
LPXNLeupaxin. (366 aa)
SHC4SHC adaptor protein 4. (634 aa)
SRMSTyrosine-protein kinase. (491 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (704 aa)
LNX1Ligand of numb-protein X 1. (784 aa)
GRB10Growth factor receptor bound protein 10. (596 aa)
H0ZCL7_TAEGUPDZ domain-containing protein. (530 aa)
IRS1Insulin receptor substrate 1. (1233 aa)
LOC100221185Uncharacterized protein. (738 aa)
CASS4Cas scaffold protein family member 4. (814 aa)
GRB2Putative growth factor receptor-bound protein 2. (217 aa)
IRS2Insulin receptor substrate 2. (1192 aa)
IGF1RTyrosine-protein kinase receptor. (1363 aa)
LOC100227679Tyrosine-protein phosphatase non-receptor type. (432 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (137 aa)
YES1Tyrosine-protein kinase. (541 aa)
HGFACPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (586 aa)
RAC2Rac family small GTPase 2. (206 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
HABP2Uncharacterized protein. (556 aa)
ERBB4Receptor protein-tyrosine kinase. (1244 aa)
DOCK1Uncharacterized protein; Belongs to the DOCK family. (1893 aa)
COL22A1Collagen type XXII alpha 1 chain. (1616 aa)
KHDRBS2KH RNA binding domain containing, signal transduction associated 2. (358 aa)
GAB2GRB2 associated binding protein 2. (680 aa)
CD2APCD2 associated protein. (637 aa)
H0ZT70_TAEGUKIND domain-containing protein. (632 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1604 aa)
CBLBCbl proto-oncogene B. (1025 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type 1. (432 aa)
BTKTyrosine-protein kinase. (662 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (359 aa)
INSRRUncharacterized protein. (1323 aa)
FRS3Fibroblast growth factor receptor substrate 3. (481 aa)
SHC1SHC adaptor protein 1. (609 aa)
RAPGEF1Uncharacterized protein. (1232 aa)
STAP2Signal-transducing adaptor protein 2 isoform X1. (292 aa)
ENSTGUP00000019835annotation not available (1860 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1054 aa)
GRAPUncharacterized protein. (358 aa)
PIK3R2Uncharacterized protein. (727 aa)
LOC100222362Phosphoinositide phospholipase C. (1311 aa)
BLNKUncharacterized protein. (601 aa)
PIK3CBUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
FYNTyrosine-protein kinase. (537 aa)
LOC100225168Tyrosine-protein kinase CSK. (450 aa)
FGRTyrosine-protein kinase. (617 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (420 aa)
ARL9ADP ribosylation factor like GTPase 9; Belongs to the small GTPase superfamily. Arf family. (475 aa)
ENSTGUP00000024560annotation not available (98 aa)
LYNTyrosine-protein kinase. (605 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (1231 aa)
LRIT3Leucine rich repeat, Ig-like and transmembrane domains 3. (636 aa)
RASL11ARAS like family 11 member A. (286 aa)
TXKTXK tyrosine kinase. (546 aa)
LOC100221170Uncharacterized protein. (298 aa)
LOC100220690Uncharacterized protein. (231 aa)
IRS4Uncharacterized protein. (1150 aa)
ENSTGUP00000027661annotation not available (73 aa)
CRKUncharacterized protein. (305 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
CRKLUncharacterized protein. (303 aa)
LOC100228496Uncharacterized protein. (250 aa)
LOC100221871Uncharacterized protein. (355 aa)
ELMO2Engulfment and cell motility 2. (732 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (555 aa)
CBLUncharacterized protein. (871 aa)
DOCK2Dedicator of cytokinesis 2. (923 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
ENSTGUP00000032818Muscle M-line assembly protein unc-89-like. (2064 aa)
ENSTGUP00000034337annotation not available (812 aa)
LOC100227341Uncharacterized protein; Belongs to the DOCK family. (1821 aa)
RAPH1Ras association (RalGDS/AF-6) and pleckstrin homology domains 1. (1278 aa)
RALGPS1Ral GEF with PH domain and SH3 binding motif 1. (586 aa)
LOC115494591Protein-tyrosine kinase 2-beta. (1047 aa)
GRAP2Uncharacterized protein. (296 aa)
KHDRBS3KH RNA binding domain containing, signal transduction associated 3. (420 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (2086 aa)
FRS2Fibroblast growth factor receptor substrate 2. (529 aa)
RASGEF1CRasGEF domain family member 1C. (481 aa)
DOCK2-2Uncharacterized protein; Belongs to the DOCK family. (1827 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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