13 items (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (846 aa)
	LOC100221185	Uncharacterized protein. (738 aa)
	RAC2	Rac family small GTPase 2. (206 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	TIAM1	T cell lymphoma invasion and metastasis 1. (1604 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1054 aa)
	PIK3R2	Uncharacterized protein. (727 aa)
	PIK3CB	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	IRS4	Uncharacterized protein. (1150 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (878 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (555 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	LOC100221185	ENSTGUP00000031570	ENSTGUP00000008408	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.956
AKT1	PDPK1	ENSTGUP00000031570	ENSTGUP00000029735	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide dependent protein kinase 1.	0.990
AKT1	PIK3CA	ENSTGUP00000031570	ENSTGUP00000011093	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.965
AKT1	PIK3CB	ENSTGUP00000031570	ENSTGUP00000021600	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.962
AKT1	PIK3CD	ENSTGUP00000031570	ENSTGUP00000019923	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.962
AKT1	PIK3R1	ENSTGUP00000031570	ENSTGUP00000003114	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase regulatory subunit 1.	0.956
AKT1	PIK3R2	ENSTGUP00000031570	ENSTGUP00000020249	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.956
AKT1	RAC2	ENSTGUP00000031570	ENSTGUP00000010983	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Rac family small GTPase 2.	0.441
IRS4	LOC100221185	ENSTGUP00000027489	ENSTGUP00000008408	Uncharacterized protein.	Uncharacterized protein.	0.969
IRS4	PIK3CA	ENSTGUP00000027489	ENSTGUP00000011093	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.965
IRS4	PIK3CB	ENSTGUP00000027489	ENSTGUP00000021600	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.960
IRS4	PIK3CD	ENSTGUP00000027489	ENSTGUP00000019923	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.955
IRS4	PIK3R1	ENSTGUP00000027489	ENSTGUP00000003114	Uncharacterized protein.	Phosphoinositide-3-kinase regulatory subunit 1.	0.969
IRS4	PIK3R2	ENSTGUP00000027489	ENSTGUP00000020249	Uncharacterized protein.	Uncharacterized protein.	0.969
LOC100221185	AKT1	ENSTGUP00000008408	ENSTGUP00000031570	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.956
LOC100221185	IRS4	ENSTGUP00000008408	ENSTGUP00000027489	Uncharacterized protein.	Uncharacterized protein.	0.969
LOC100221185	PDPK1	ENSTGUP00000008408	ENSTGUP00000029735	Uncharacterized protein.	3-phosphoinositide dependent protein kinase 1.	0.967
LOC100221185	PIK3CA	ENSTGUP00000008408	ENSTGUP00000011093	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.987
LOC100221185	PIK3CB	ENSTGUP00000008408	ENSTGUP00000021600	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.982
LOC100221185	PIK3CD	ENSTGUP00000008408	ENSTGUP00000019923	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.983