(60 nodes) Mixed, incl. Cortical cytoskeleton organization, and RHOB GTPase cycle network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYO9B	Myosin IXB. (2044 aa)
	UBXN11	SEP domain-containing protein. (447 aa)
	NET1	Neuroepithelial cell transforming 1. (594 aa)
	ARHGDIA	Rho GDP dissociation inhibitor alpha. (272 aa)
	IQGAP3	IQ motif containing GTPase activating protein 3. (1640 aa)
	MYO9A	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2656 aa)
	FHDC1	FH2 domain containing 1. (1137 aa)
	ARHGAP36	Rho-GAP domain-containing protein. (507 aa)
	RHOBTB1	Rho related BTB domain containing 1. (694 aa)
	RHOD	Ras homolog family member D. (198 aa)
	RHOF	Ras homolog family member F, filopodia associated. (268 aa)
	TRIO	Trio Rho guanine nucleotide exchange factor. (2890 aa)
	H0ZBL0_TAEGU	Uncharacterized protein. (208 aa)
	LOC115497921	Uncharacterized protein. (726 aa)
	PLXNB1	Plexin B1. (2206 aa)
	ERP27	Endoplasmic reticulum protein 27. (403 aa)
	ARHGAP19	Rho-GAP domain-containing protein. (519 aa)
	BCR	Uncharacterized protein. (1349 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1655 aa)
	RHOV	Uncharacterized protein. (231 aa)
	RND3	Rho family GTPase 3. (244 aa)
	ARHGEF11	DH domain-containing protein. (1206 aa)
	SPATA13	Uncharacterized protein. (1326 aa)
	ARHGAP1	Rho GTPase activating protein 1. (445 aa)
	ENSTGUP00000020504	annotation not available (663 aa)
	ARHGEF4	Uncharacterized protein. (2247 aa)
	ENSTGUP00000020764	annotation not available (782 aa)
	CHN2	Rho-GAP domain-containing protein. (518 aa)
	ENSTGUP00000022132	annotation not available (192 aa)
	LOC100225218	Kelch-like ECH-associated protein 1. (614 aa)
	PFN1	Profilin 1. (140 aa)
	DIAPH2	Uncharacterized protein. (1216 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (1032 aa)
	DAAM2	Dishevelled associated activator of morphogenesis 2. (1084 aa)
	DIAPH3	Uncharacterized protein. (1145 aa)
	RHOB	Ras homolog family member B. (196 aa)
	LOC115494853	Rho-related BTB domain-containing protein 2 isoform X1. (640 aa)
	DAAM1	Dishevelled associated activator of morphogenesis 1. (1079 aa)
	ABR	ABR activator of RhoGEF and GTPase. (861 aa)
	KALRN	Uncharacterized protein. (2983 aa)
	FMNL2	Formin like 2. (1112 aa)
	RND1	Rho-related GTP-binding protein Rho6. (345 aa)
	ARHGEF28	Rho guanine nucleotide exchange factor 28. (1372 aa)
	PLXNB2	Plexin B2. (1881 aa)
	KLHL13	BTB domain-containing protein. (594 aa)
	ARHGAP12	Uncharacterized protein. (881 aa)
	RHOC	Rho-related GTP-binding protein RhoC isoform X3. (387 aa)
	RHOBTB2	Rho related BTB domain containing 2. (821 aa)
	ARHGDIG	Rho GDP-dissociation inhibitor 3. (320 aa)
	FMNL1	Formin-like protein 1. (651 aa)
	IQGAP2	IQ motif containing GTPase activating protein 2. (1659 aa)
	RAC3	Rac family small GTPase 3. (229 aa)
	ENSTGUP00000035053	annotation not available (864 aa)
	ARHGAP27	Rho GTPase-activating protein 27 isoform X1. (855 aa)
	DIRAS2	DIRAS family GTPase 2. (199 aa)
	TIAM2	DH domain-containing protein. (1725 aa)
	ENSTGUP00000036060	annotation not available (197 aa)
	RHOH	Ras homolog family member H. (191 aa)
	ENSTGUP00000037438	annotation not available (333 aa)
	RND2	Rho family GTPase 2. (388 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABR	ARHGAP1	ENSTGUP00000030746	ENSTGUP00000019038	ABR activator of RhoGEF and GTPase.	Rho GTPase activating protein 1.	0.598
ABR	ARHGAP12	ENSTGUP00000030746	ENSTGUP00000032820	ABR activator of RhoGEF and GTPase.	Uncharacterized protein.	0.420
ABR	ARHGAP19	ENSTGUP00000030746	ENSTGUP00000010034	ABR activator of RhoGEF and GTPase.	Rho-GAP domain-containing protein.	0.432
ABR	ARHGAP27	ENSTGUP00000030746	ENSTGUP00000035079	ABR activator of RhoGEF and GTPase.	Rho GTPase-activating protein 27 isoform X1.	0.420
ABR	ARHGAP36	ENSTGUP00000030746	ENSTGUP00000005469	ABR activator of RhoGEF and GTPase.	Rho-GAP domain-containing protein.	0.407
ABR	CHN2	ENSTGUP00000030746	ENSTGUP00000021348	ABR activator of RhoGEF and GTPase.	Rho-GAP domain-containing protein.	0.432
ABR	DAAM1	ENSTGUP00000030746	ENSTGUP00000029241	ABR activator of RhoGEF and GTPase.	Dishevelled associated activator of morphogenesis 1.	0.451
ABR	DAAM2	ENSTGUP00000030746	ENSTGUP00000025966	ABR activator of RhoGEF and GTPase.	Dishevelled associated activator of morphogenesis 2.	0.451
ABR	ENSTGUP00000036060	ENSTGUP00000030746	ENSTGUP00000036060	ABR activator of RhoGEF and GTPase.	annotation not available	0.452
ABR	FHDC1	ENSTGUP00000030746	ENSTGUP00000005221	ABR activator of RhoGEF and GTPase.	FH2 domain containing 1.	0.431
ABR	LOC115494853	ENSTGUP00000030746	ENSTGUP00000028581	ABR activator of RhoGEF and GTPase.	Rho-related BTB domain-containing protein 2 isoform X1.	0.414
ABR	MYO9A	ENSTGUP00000030746	ENSTGUP00000004618	ABR activator of RhoGEF and GTPase.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.685
ABR	MYO9B	ENSTGUP00000030746	ENSTGUP00000000474	ABR activator of RhoGEF and GTPase.	Myosin IXB.	0.685
ABR	RAC3	ENSTGUP00000030746	ENSTGUP00000034636	ABR activator of RhoGEF and GTPase.	Rac family small GTPase 3.	0.422
ABR	RHOB	ENSTGUP00000030746	ENSTGUP00000027521	ABR activator of RhoGEF and GTPase.	Ras homolog family member B.	0.485
ABR	RHOBTB1	ENSTGUP00000030746	ENSTGUP00000005477	ABR activator of RhoGEF and GTPase.	Rho related BTB domain containing 1.	0.414
ABR	RHOBTB2	ENSTGUP00000030746	ENSTGUP00000033272	ABR activator of RhoGEF and GTPase.	Rho related BTB domain containing 2.	0.414
ABR	RHOC	ENSTGUP00000030746	ENSTGUP00000032984	ABR activator of RhoGEF and GTPase.	Rho-related GTP-binding protein RhoC isoform X3.	0.485
ABR	RHOD	ENSTGUP00000030746	ENSTGUP00000006140	ABR activator of RhoGEF and GTPase.	Ras homolog family member D.	0.452
ABR	RHOF	ENSTGUP00000030746	ENSTGUP00000006251	ABR activator of RhoGEF and GTPase.	Ras homolog family member F, filopodia associated.	0.452