STRINGSTRING
TEAD3 TEAD3 HECW1 HECW1 VGLL1 VGLL1 MSN MSN PRKCZ PRKCZ VGLL4 VGLL4 CRB1 CRB1 MPDZ MPDZ PARD6A PARD6A STK4 STK4 AMOT AMOT AMOTL2 AMOTL2 DTX4 DTX4 WWP2 WWP2 LLGL2 LLGL2 PARD6G PARD6G NF2 NF2 HECW2 HECW2 EZR EZR LATS1 LATS1 WWTR1 WWTR1 WWP1 WWP1 GOPC GOPC TEAD4 TEAD4 LLGL1 LLGL1 PARD3 PARD3 RHOJ RHOJ PLEKHA7 PLEKHA7 FRMD1 FRMD1 HIVEP3 HIVEP3 NDFIP2 NDFIP2 PODXL PODXL INSM2 INSM2 CFTR CFTR LOC100230978 LOC100230978 LOC100230322 LOC100230322 LOC115497907 LOC115497907 MPP3 MPP3 MOB1B MOB1B EPB41L5 EPB41L5 DTX1 DTX1 SLC9A3R1 SLC9A3R1 LOC100221634 LOC100221634 STK3 STK3 NUMB NUMB CRB2 CRB2 RDX RDX PATJ PATJ SLC9A3R2 SLC9A3R2 MPP7 MPP7 LNX2 LNX2 AMOTL1 AMOTL1 H0Z4A8_TAEGU H0Z4A8_TAEGU PARD3B PARD3B PRKCI PRKCI PRKCE PRKCE TEAD1 TEAD1 LATS2 LATS2 SAV1 SAV1 MPP5 MPP5 YAP1 YAP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TEAD3Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (432 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1614 aa)
VGLL1Vestigial like family member 1. (159 aa)
MSNMoesin. (580 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
VGLL4Vestigial like family member 4. (289 aa)
CRB1Uncharacterized protein. (1407 aa)
MPDZMultiple PDZ domain crumbs cell polarity complex component. (2137 aa)
PARD6APar-6 family cell polarity regulator alpha. (357 aa)
STK4Serine/threonine kinase 4. (533 aa)
AMOTAngiomotin. (926 aa)
AMOTL2Angiomotin like 2. (691 aa)
DTX4Deltex E3 ubiquitin ligase 4. (617 aa)
WWP2E3 ubiquitin-protein ligase. (877 aa)
LLGL2LLGL scribble cell polarity complex component 2. (1025 aa)
PARD6GPar-6 family cell polarity regulator gamma. (568 aa)
NF2Neurofibromin 2. (595 aa)
HECW2Uncharacterized protein. (1562 aa)
EZREzrin. (586 aa)
LATS1Large tumor suppressor kinase 1. (1138 aa)
WWTR1WW domain containing transcription regulator 1. (382 aa)
WWP1E3 ubiquitin-protein ligase. (925 aa)
GOPCPDZ domain-containing protein. (631 aa)
TEAD4TEA domain transcription factor 4. (492 aa)
LLGL1Lgl_C domain-containing protein. (1106 aa)
PARD3Par-3 family cell polarity regulator. (1350 aa)
RHOJRas homolog family member J. (289 aa)
PLEKHA7PH domain-containing protein. (1477 aa)
FRMD1FERM domain containing 1. (565 aa)
HIVEP3Human immunodeficiency virus type I enhancer binding protein 3. (2290 aa)
NDFIP2Nedd4 family interacting protein 2. (302 aa)
PODXLUncharacterized protein. (602 aa)
INSM2INSM transcriptional repressor 2. (402 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1485 aa)
LOC100230978FERM domain-containing protein. (660 aa)
LOC100230322Uncharacterized protein. (680 aa)
LOC115497907Par-6 family cell polarity regulator beta. (372 aa)
MPP3Membrane palmitoylated protein 3; Belongs to the MAGUK family. (332 aa)
MOB1BUncharacterized protein. (216 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (766 aa)
DTX1LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase DTX1. (608 aa)
SLC9A3R1SLC9A3 regulator 1. (333 aa)
LOC100221634Partitioning defective 6 homolog beta. (372 aa)
STK3Serine/threonine kinase 3. (510 aa)
NUMBNUMB endocytic adaptor protein. (671 aa)
CRB2Uncharacterized protein. (1464 aa)
RDXRadixin. (594 aa)
PATJUncharacterized protein. (1813 aa)
SLC9A3R2SLC9A3 regulator 2. (551 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (597 aa)
LNX2Ligand of numb-protein X 2. (687 aa)
AMOTL1Angiomotin like 1. (964 aa)
H0Z4A8_TAEGUCENP-T_C domain-containing protein. (640 aa)
PARD3BPar-3 family cell polarity regulator beta. (1201 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (470 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (743 aa)
TEAD1Transcriptional enhancer factor TEF-1 isoform X4. (442 aa)
LATS2Non-specific serine/threonine protein kinase. (1153 aa)
SAV1Salvador family WW domain containing protein 1. (379 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
YAP1Uncharacterized protein. (504 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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