(26 nodes) Terpenoid backbone biosynthesis, and UbiA prenyltransferase family network (Taeniopygia guttata)

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	FNTA	Farnesyltransferase, CAAX box, alpha. (368 aa)
	DHDDS	Alkyl transferase; Belongs to the UPP synthase family. (333 aa)
	PDSS1	Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (382 aa)
	COQ2	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (347 aa)
	HMGCR	3-hydroxy-3-methylglutaryl coenzyme A reductase. (1030 aa)
	MVK	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
	LOC100223864	Uncharacterized protein. (409 aa)
	NUS1	NUS1 dehydrodolichyl diphosphate synthase subunit. (282 aa)
	PDSS2	Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. (389 aa)
	FDPS	Farnesyl diphosphate synthase. (345 aa)
	HMGCS2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (507 aa)
	IDI1	Nudix hydrolase domain-containing protein. (266 aa)
	FBXO30	F-box protein 30. (757 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (469 aa)
	GGPS1	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (434 aa)
	H1A298_TAEGU	Uncharacterized protein. (362 aa)
	PGGT1B	Protein geranylgeranyltransferase type I subunit beta. (245 aa)
	ICMT	Protein-S-isoprenylcysteine O-methyltransferase. (466 aa)
	LOC115492109	Prenyl protein peptidase. (314 aa)
	CHURC1	Churchill domain containing 1. (112 aa)
	ACOT13	4HBT domain-containing protein. (387 aa)
	PMVK	Phosphomevalonate kinase. (205 aa)
	ENSTGUP00000035357	annotation not available (690 aa)
	RUSC1	RUN and SH3 domain containing 1. (1209 aa)
	UBIAD1	UbiA prenyltransferase domain containing 1. (338 aa)
	ENSTGUP00000038471	annotation not available (109 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACOT13	UBIAD1	ENSTGUP00000032351	ENSTGUP00000037680	4HBT domain-containing protein.	UbiA prenyltransferase domain containing 1.	0.936
CHURC1	DHDDS	ENSTGUP00000031189	ENSTGUP00000001059	Churchill domain containing 1.	Alkyl transferase; Belongs to the UPP synthase family.	0.438
CHURC1	ENSTGUP00000038471	ENSTGUP00000031189	ENSTGUP00000038471	Churchill domain containing 1.	annotation not available	0.596
CHURC1	FNTA	ENSTGUP00000031189	ENSTGUP00000000282	Churchill domain containing 1.	Farnesyltransferase, CAAX box, alpha.	0.964
CHURC1	H1A298_TAEGU	ENSTGUP00000031189	ENSTGUP00000025949	Churchill domain containing 1.	Uncharacterized protein.	0.596
CHURC1	HMGCR	ENSTGUP00000031189	ENSTGUP00000006291	Churchill domain containing 1.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.437
CHURC1	ICMT	ENSTGUP00000031189	ENSTGUP00000028835	Churchill domain containing 1.	Protein-S-isoprenylcysteine O-methyltransferase.	0.505
CHURC1	LOC115492109	ENSTGUP00000031189	ENSTGUP00000031060	Churchill domain containing 1.	Prenyl protein peptidase.	0.596
CHURC1	ZMPSTE24	ENSTGUP00000031189	ENSTGUP00000023005	Churchill domain containing 1.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.506
COQ2	DHDDS	ENSTGUP00000002262	ENSTGUP00000001059	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Alkyl transferase; Belongs to the UPP synthase family.	0.881
COQ2	ENSTGUP00000035357	ENSTGUP00000002262	ENSTGUP00000035357	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	annotation not available	0.451
COQ2	FBXO30	ENSTGUP00000002262	ENSTGUP00000021388	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	F-box protein 30.	0.655
COQ2	FDPS	ENSTGUP00000002262	ENSTGUP00000016832	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Farnesyl diphosphate synthase.	0.655
COQ2	GGPS1	ENSTGUP00000002262	ENSTGUP00000025781	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.771
COQ2	HMGCR	ENSTGUP00000002262	ENSTGUP00000006291	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.697
COQ2	IDI1	ENSTGUP00000002262	ENSTGUP00000020955	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Nudix hydrolase domain-containing protein.	0.943
COQ2	MVK	ENSTGUP00000002262	ENSTGUP00000007608	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.617
COQ2	NUS1	ENSTGUP00000002262	ENSTGUP00000012256	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	NUS1 dehydrodolichyl diphosphate synthase subunit.	0.881
COQ2	PDSS1	ENSTGUP00000002262	ENSTGUP00000001169	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family.	0.963
COQ2	PDSS2	ENSTGUP00000002262	ENSTGUP00000012536	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family.	0.963