STRINGSTRING
LOC115497664 LOC115497664 CTPS1 CTPS1 AMPD1 AMPD1 NT5C1A NT5C1A DCK DCK PDE5A PDE5A H0YWD7_TAEGU H0YWD7_TAEGU HPRT1 HPRT1 CANT1 CANT1 TK1 TK1 PDE8B PDE8B NUDT16L1 NUDT16L1 ADCY5 ADCY5 ENTPD6 ENTPD6 ADA ADA NT5C3A NT5C3A UPRT UPRT PNP PNP UCKL1 UCKL1 AMPD3 AMPD3 ADSS2 ADSS2 PDE3B PDE3B CMPK1 CMPK1 PDE11A PDE11A H0ZFS5_TAEGU H0ZFS5_TAEGU ENTPD1 ENTPD1 NT5C2 NT5C2 PDE7B PDE7B GMPS GMPS ENPP3 ENPP3 RRM2B RRM2B PDE3A PDE3A ADA2 ADA2 RRM2 RRM2 LOC100224575 LOC100224575 NT5C3B NT5C3B NME6 NME6 NUDT2 NUDT2 DUT DUT ENTPD8 ENTPD8 DCTD DCTD LOC100220427 LOC100220427 PDE1A PDE1A AK2 AK2 NME7 NME7 NTPCR NTPCR ENTPD5 ENTPD5 AK7 AK7 ENPP1 ENPP1 UPP1 UPP1 NME2 NME2 UCK1 UCK1 PDE2A PDE2A ADK ADK LOC100218564 LOC100218564 ADCY6 ADCY6 ENTPD2 ENTPD2 NME3 NME3 CTPS2 CTPS2 LOC115496245 LOC115496245 AMPD2 AMPD2 AK3 AK3 DTYMK DTYMK MPP2 MPP2 TYMP TYMP UPP2 UPP2 NT5E NT5E RRM1 RRM1 CDA CDA NME1 NME1 ENTPD4 ENTPD4 LOC100229613 LOC100229613 AK6 AK6 AK5 AK5 PDE10A PDE10A NT5M NT5M IMPDH2 IMPDH2 H1A138_TAEGU H1A138_TAEGU PDE1C PDE1C NPR1 NPR1 AK8 AK8 GMPR GMPR DGUOK DGUOK PDE7A PDE7A
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LOC115497664Ribonucleoside-diphosphate reductase large subunit. (801 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (627 aa)
AMPD1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (742 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (350 aa)
DCKdNK domain-containing protein. (257 aa)
PDE5APhosphodiesterase. (849 aa)
H0YWD7_TAEGUUncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (490 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
CANT1Calcium activated nucleotidase 1. (532 aa)
TK1Thymidine kinase. (223 aa)
PDE8BPhosphodiesterase. (886 aa)
NUDT16L1Nudix hydrolase 16 like 1. (305 aa)
ADCY5Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1216 aa)
ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (442 aa)
ADAAdenosine deaminase. (359 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa)
UPRTUracil phosphoribosyltransferase homolog. (277 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (324 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (526 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (792 aa)
ADSS2Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (463 aa)
PDE3BPhosphodiesterase. (1112 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (224 aa)
PDE11APhosphodiesterase. (915 aa)
H0ZFS5_TAEGUUncharacterized protein. (124 aa)
ENTPD1Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (522 aa)
NT5C2Uncharacterized protein. (592 aa)
PDE7BPhosphodiesterase 7B; Belongs to the cyclic nucleotide phosphodiesterase family. (407 aa)
GMPSGuanine monophosphate synthase. (693 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase 3. (888 aa)
RRM2BRibonucleotide reductase regulatory TP53 inducible subunit M2B. (347 aa)
PDE3APhosphodiesterase. (930 aa)
ADA2Adenosine deaminase 2. (515 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (397 aa)
LOC100224575Uncharacterized protein. (358 aa)
NT5C3B5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (289 aa)
NME6Nucleoside diphosphate kinase. (262 aa)
NUDT2Nudix hydrolase 2. (148 aa)
DUTDeoxyuridine triphosphatase. (166 aa)
ENTPD8Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (648 aa)
DCTDdCMP deaminase. (380 aa)
LOC100220427dNK domain-containing protein. (270 aa)
PDE1APhosphodiesterase. (552 aa)
AK2Adenylate kinase 2; Belongs to the adenylate kinase family. (246 aa)
NME7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (387 aa)
NTPCRAAA domain-containing protein. (236 aa)
ENTPD5Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (428 aa)
AK7Uncharacterized protein. (726 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (908 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (351 aa)
NME2Nucleoside diphosphate kinase. (325 aa)
UCK1Uridine-cytidine kinase; Belongs to the uridine kinase family. (214 aa)
PDE2APhosphodiesterase. (949 aa)
ADKAdenosine kinase. (448 aa)
LOC100218564PRK domain-containing protein. (572 aa)
ADCY6Guanylate cyclase domain-containing protein. (1156 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (505 aa)
NME3Nucleoside diphosphate kinase. (198 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (609 aa)
LOC115496245GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (251 aa)
AMPD2Uncharacterized protein. (819 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (225 aa)
DTYMKDeoxythymidylate kinase. (230 aa)
MPP2MAGUK p55 subfamily member 2-like. (560 aa)
TYMPThymidine phosphorylase. (462 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (342 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (578 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (152 aa)
NME1Nucleoside diphosphate kinase A. (153 aa)
ENTPD4Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (699 aa)
LOC100229613Uncharacterized protein. (373 aa)
AK6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (171 aa)
AK5Uncharacterized protein; Belongs to the adenylate kinase family. (566 aa)
PDE10APhosphodiesterase. (1058 aa)
NT5MUncharacterized protein. (232 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (538 aa)
H1A138_TAEGUPDEase domain-containing protein. (968 aa)
PDE1CPhosphodiesterase. (608 aa)
NPR1Guanylate cyclase domain-containing protein. (1073 aa)
AK8Uncharacterized protein; Belongs to the adenylate kinase family. (482 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa)
DGUOKdNK domain-containing protein. (439 aa)
PDE7APhosphodiesterase 7A; Belongs to the cyclic nucleotide phosphodiesterase family. (495 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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