(44 nodes) Positive regulation of endothelial cell proliferation network (Taeniopygia guttata)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	MYDGF	Myeloid derived growth factor. (298 aa)
	SIRT6	Sirtuin 6. (348 aa)
	FLT4	Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1379 aa)
	IL10	Interleukin 10. (165 aa)
	RPTOR	Regulatory associated protein of MTOR complex 1. (1358 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (797 aa)
	LOC100230282	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (586 aa)
	SIRT1	Sirtuin 1. (750 aa)
	AGGF1	Uncharacterized protein. (707 aa)
	F3	Coagulation factor III, tissue factor. (402 aa)
	HMGB2	High mobility group box 2. (208 aa)
	VEGFC	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (468 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (501 aa)
	SCG2	Secretogranin II. (625 aa)
	VEGFD	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa)
	IGF2	IlGF domain-containing protein. (225 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1024 aa)
	HTR2B	5-hydroxytryptamine receptor 2B. (463 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1036 aa)
	MDK	Midkine. (139 aa)
	VIP	Vasoactive intestinal peptide. (215 aa)
	ADAM17	ADAM metallopeptidase domain 17. (918 aa)
	LOC115491390	Nuclear receptor subfamily 4 group A member 1. (574 aa)
	PGF	Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (255 aa)
	LOC115491349	Transcription factor Sp1. (764 aa)
	ENSTGUP00000019172	annotation not available (72 aa)
	BMP6	Bone morphogenetic protein 6. (414 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1054 aa)
	PDGFB	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (278 aa)
	LOC115491405	Serine/threonine-protein kinase receptor R3 isoform X2. (493 aa)
	LOC100224755	Transcription factor Sp1-like. (764 aa)
	ENSTGUP00000023034	annotation not available (327 aa)
	VEGFA	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (394 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
	CAV2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (163 aa)
	APLNR	Uncharacterized protein. (371 aa)
	APELA	Apelin receptor early endogenous ligand. (54 aa)
	NRARP	NOTCH regulated ankyrin repeat protein. (117 aa)
	AGTR1	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	LOC100231563	Nuclear receptor subfamily 4 group A member 1. (574 aa)
	JCAD	Junctional cadherin 5 associated. (1330 aa)
	ECM1	Extracellular matrix protein 1. (419 aa)
	VASH2	Vasohibin 2. (367 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGTR1	APLNR	ENSTGUP00000034966	ENSTGUP00000031996	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.705
AGTR1	ENSTGUP00000019172	ENSTGUP00000034966	ENSTGUP00000019172	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	annotation not available	0.690
APELA	APLNR	ENSTGUP00000032014	ENSTGUP00000031996	Apelin receptor early endogenous ligand.	Uncharacterized protein.	0.900
APELA	ENSTGUP00000019172	ENSTGUP00000032014	ENSTGUP00000019172	Apelin receptor early endogenous ligand.	annotation not available	0.660
APLNR	AGTR1	ENSTGUP00000031996	ENSTGUP00000034966	Uncharacterized protein.	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.705
APLNR	APELA	ENSTGUP00000031996	ENSTGUP00000032014	Uncharacterized protein.	Apelin receptor early endogenous ligand.	0.900
APLNR	ENSTGUP00000019172	ENSTGUP00000031996	ENSTGUP00000019172	Uncharacterized protein.	annotation not available	0.912
BMP6	BMPR2	ENSTGUP00000019464	ENSTGUP00000010438	Bone morphogenetic protein 6.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.972
BMP6	LOC100230282	ENSTGUP00000019464	ENSTGUP00000003374	Bone morphogenetic protein 6.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.403
BMP6	LOC115491405	ENSTGUP00000019464	ENSTGUP00000021756	Bone morphogenetic protein 6.	Serine/threonine-protein kinase receptor R3 isoform X2.	0.403
BMPR2	BMP6	ENSTGUP00000010438	ENSTGUP00000019464	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 6.	0.972
BMPR2	LOC100230282	ENSTGUP00000010438	ENSTGUP00000003374	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.814
BMPR2	LOC115491405	ENSTGUP00000010438	ENSTGUP00000021756	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Serine/threonine-protein kinase receptor R3 isoform X2.	0.961
BMPR2	TGFBR1	ENSTGUP00000010438	ENSTGUP00000006937	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.611
CAV2	ITGB3	ENSTGUP00000030045	ENSTGUP00000003271	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Integrin beta; Belongs to the integrin beta chain family.	0.912
ENSTGUP00000019172	AGTR1	ENSTGUP00000019172	ENSTGUP00000034966	annotation not available	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.690
ENSTGUP00000019172	APELA	ENSTGUP00000019172	ENSTGUP00000032014	annotation not available	Apelin receptor early endogenous ligand.	0.660
ENSTGUP00000019172	APLNR	ENSTGUP00000019172	ENSTGUP00000031996	annotation not available	Uncharacterized protein.	0.912
FGF7	FLT4	ENSTGUP00000019495	ENSTGUP00000001030	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.831
FGF7	KDR	ENSTGUP00000019495	ENSTGUP00000029011	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.825