STRINGSTRING
RAF1 RAF1 BRAF BRAF MAP3K1 MAP3K1 MAP3K14 MAP3K14 MAP3K8 MAP3K8 RIPK2 RIPK2 MAP3K9 MAP3K9 LRRK2 LRRK2 MAP3K15 MAP3K15 ENSTGUP00000021869 ENSTGUP00000021869 MAP3K7 MAP3K7 MAP3K21 MAP3K21 PBK PBK MAP3K5 MAP3K5 ENSTGUP00000028403 ENSTGUP00000028403 RIPK1 RIPK1 MAP3K20 MAP3K20 MOS MOS LOC115491344 LOC115491344 MAP3K2 MAP3K2 LOC115496886 LOC115496886 MAP3K13 MAP3K13 MAP3K4 MAP3K4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (1062 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (765 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1654 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (937 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (487 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (553 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase. (1049 aa)
LRRK2Leucine rich repeat kinase 2. (2509 aa)
MAP3K15Mitogen-activated protein kinase kinase kinase 15. (1352 aa)
ENSTGUP00000021869annotation not available (838 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (627 aa)
MAP3K21Mitogen-activated protein kinase kinase kinase 21. (1070 aa)
PBKLymphokine-activated killer T-cell-originated protein kinase. (687 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1360 aa)
ENSTGUP00000028403annotation not available (130 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (690 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (476 aa)
MOSProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (349 aa)
LOC115491344Mitogen-activated protein kinase kinase kinase 12-like. (783 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (624 aa)
LOC115496886Protein kinase domain-containing protein. (554 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase. (956 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1601 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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