STRINGSTRING
UMPS UMPS CTPS1 CTPS1 DCK DCK NT5C3A NT5C3A DPYD DPYD UPRT UPRT H0Z9I5_TAEGU H0Z9I5_TAEGU UCKL1 UCKL1 DHODH DHODH CMPK1 CMPK1 ENTPD7 ENTPD7 UPB1 UPB1 TYMS TYMS TBPL1 TBPL1 NME6 NME6 DUT DUT DCTD DCTD LOC100220427 LOC100220427 NME7 NME7 ENTPD5 ENTPD5 UPP1 UPP1 NME2 NME2 UCK1 UCK1 LOC100218564 LOC100218564 NME3 NME3 CTPS2 CTPS2 CMPK2 CMPK2 AK3 AK3 DTYMK DTYMK TYMP TYMP UPP2 UPP2 CDA CDA NME1 NME1 ENTPD4 ENTPD4 NT5M NT5M NME5 NME5 ENSTGUP00000036805 ENSTGUP00000036805
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UMPSUridine monophosphate synthetase. (481 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (627 aa)
DCKdNK domain-containing protein. (257 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1017 aa)
UPRTUracil phosphoribosyltransferase homolog. (277 aa)
H0Z9I5_TAEGUThioredoxin domain-containing protein. (158 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (526 aa)
DHODHDHO_dh domain-containing protein. (392 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (224 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (682 aa)
UPB1Beta-ureidopropionase 1. (466 aa)
TYMSThymidylat_synt domain-containing protein. (343 aa)
TBPL1TATA-box binding protein like 1. (183 aa)
NME6Nucleoside diphosphate kinase. (262 aa)
DUTDeoxyuridine triphosphatase. (166 aa)
DCTDdCMP deaminase. (380 aa)
LOC100220427dNK domain-containing protein. (270 aa)
NME7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (387 aa)
ENTPD5Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (428 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (351 aa)
NME2Nucleoside diphosphate kinase. (325 aa)
UCK1Uridine-cytidine kinase; Belongs to the uridine kinase family. (214 aa)
LOC100218564PRK domain-containing protein. (572 aa)
NME3Nucleoside diphosphate kinase. (198 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (609 aa)
CMPK2Cytidine/uridine monophosphate kinase 2. (56 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (225 aa)
DTYMKDeoxythymidylate kinase. (230 aa)
TYMPThymidine phosphorylase. (462 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (342 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (152 aa)
NME1Nucleoside diphosphate kinase A. (153 aa)
ENTPD4Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (699 aa)
NT5MUncharacterized protein. (232 aa)
NME5NME/NM23 family member 5; Belongs to the NDK family. (232 aa)
ENSTGUP00000036805annotation not available (274 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.