STRINGSTRING
EME1 EME1 CAV2 CAV2 H1A086_TAEGU H1A086_TAEGU MUC1 MUC1 RRM1 RRM1 TFAP4 TFAP4 PPP1R10-2 PPP1R10-2 ENSTGUP00000031243 ENSTGUP00000031243 MAD2L1BP MAD2L1BP ENSTGUP00000031407 ENSTGUP00000031407 LOC100222344 LOC100222344 ENSTGUP00000031587 ENSTGUP00000031587 PTPN6 PTPN6 CDK5RAP2 CDK5RAP2 DDR2 DDR2 WAC WAC AVEN AVEN PSMG2 PSMG2 SRSF3 SRSF3 SDE2 SDE2 LOC115494026 LOC115494026 ORC1 ORC1 GIGYF2 GIGYF2 LOC115493600 LOC115493600 BTG1 BTG1 LOC115498196 LOC115498196 C10orf90 C10orf90 CACNB4 CACNB4 DCUN1D3 DCUN1D3 CDC42 CDC42 ERCC3 ERCC3 DYNLT3 DYNLT3 NOP53 NOP53 STOX1 STOX1 PLRG1 PLRG1 ENSTGUP00000037304 ENSTGUP00000037304 TP73 TP73 ENSTGUP00000037836 ENSTGUP00000037836 PLK1 PLK1 ANXA1 ANXA1 RAD50 RAD50 LOC115490804 LOC115490804 H0ZR88_TAEGU H0ZR88_TAEGU CDKN1B CDKN1B ATM ATM TTK TTK NSMCE2 NSMCE2 BORA BORA MTBP MTBP RB1 RB1 INTS13 INTS13 RRM2B RRM2B FBXO43 FBXO43 TTLL12 TTLL12 NBN NBN BRCA2 BRCA2 BUB3 BUB3 MTRF1L MTRF1L APPL2 APPL2 HECA HECA FBXO7 FBXO7 PRKDC PRKDC ZFYVE19 ZFYVE19 LOC100229685 LOC100229685 KLHL22 KLHL22 FGF8 FGF8 PIDD1 PIDD1 ZWILCH ZWILCH CPSF3 CPSF3 ADAM17 ADAM17 RRM2 RRM2 DLGAP5 DLGAP5 GEN1 GEN1 CASP2 CASP2 FZD3 FZD3 LOC100230026-2 LOC100230026-2 VPS4A VPS4A LOC100222335 LOC100222335 E4F1 E4F1 USP47 USP47 ECD ECD ANAPC4 ANAPC4 CDK5RAP3 CDK5RAP3 INTS3 INTS3 BRINP2 BRINP2 RAD17 RAD17 NME6 NME6 MIIP MIIP SCRIB SCRIB RPRM RPRM SYF2 SYF2 AMBRA1 AMBRA1 FOXN3 FOXN3 CTDSP1 CTDSP1 GPR132 GPR132 PDGFB PDGFB LOC100223123 LOC100223123 CTC1 CTC1 FBXO31 FBXO31 TOM1L1 TOM1L1 ANGEL2 ANGEL2 MKI67 MKI67 FOXO4 FOXO4 ENSTGUP00000021498 ENSTGUP00000021498 ENSTGUP00000021519 ENSTGUP00000021519 PPP1R10 PPP1R10 CKS1B CKS1B BABAM2 BABAM2 CDC73 CDC73 ANAPC15 ANAPC15 XRCC3 XRCC3 ENSTGUP00000032655 ENSTGUP00000032655 RAD9A RAD9A LOC100226358 LOC100226358 MRE11 MRE11 TIPIN TIPIN TFDP1 TFDP1 TAOK3 TAOK3 CUL4A CUL4A PCID2 PCID2 PMS2 PMS2 CHFR CHFR MAD1L1 MAD1L1 PTPN3 PTPN3 TICRR TICRR CUL3 CUL3 CDK10 CDK10 CHEK2 CHEK2 TTC28 TTC28 CDT1 CDT1 CYLD CYLD E2F7 E2F7 RBL2 RBL2 RAD51C RAD51C TEX14 TEX14 BUB1 BUB1 APPL1 APPL1 NLE1 NLE1 HUS1 HUS1 SMPD3 SMPD3 FANCD2 FANCD2 RAD9B RAD9B KNTC1 KNTC1 TAOK1 TAOK1 CDC25B CDC25B CDC7 CDC7 BCL7A BCL7A LOC115495410 LOC115495410 ANAPC5 ANAPC5 POLDIP2 POLDIP2 BIRC5 BIRC5 EDN1 EDN1 ANAPC7 ANAPC7 MSH6 MSH6 MSH2 MSH2 YWHAE YWHAE CCND1 CCND1 CDK1 CDK1 TTL TTL CDC14A CDC14A CRLF3 CRLF3 ATAD5 ATAD5 ZNF207 ZNF207 CTNNB1 CTNNB1 EIF4EBP1 EIF4EBP1 H0Z332_TAEGU H0Z332_TAEGU TOPBP1 TOPBP1 KIF14 KIF14 NEK11 NEK11 PIM3 PIM3 LOC100224554 LOC100224554 TPR TPR CUL4B CUL4B SIRT1 SIRT1 IL1B IL1B BRINP1 BRINP1 RBL1 RBL1 DTL DTL RPTOR RPTOR RINT1 RINT1 KMT2E KMT2E CENPF CENPF BRCA1 BRCA1 PSME3 PSME3 LOC100231082 LOC100231082 H0YW59_TAEGU H0YW59_TAEGU FBXW5 FBXW5 CDC6 CDC6 PKD2 PKD2 ABRAXAS1 ABRAXAS1 VPS4B VPS4B MEIOC MEIOC CDC27 CDC27 MAD2L1 MAD2L1 INHBA INHBA BTC BTC ASNS ASNS CLSPN CLSPN ANKRD17 ANKRD17 LOC100218902 LOC100218902 H0YTF5_TAEGU H0YTF5_TAEGU INIP INIP RIOK2 RIOK2 CCNH CCNH RCC1 RCC1 CHEK1 CHEK1 GAS1 GAS1 GMNN GMNN CDKN2C CDKN2C MEPCE MEPCE PKD1 PKD1 CDC14B CDC14B ZMPSTE24 ZMPSTE24 LOC115497664 LOC115497664 UIMC1 UIMC1 CKS2 CKS2 BTG4 BTG4 ZW10 ZW10 KLHL18 KLHL18 CDC23 CDC23 CDC25A CDC25A LSM10 LSM10 ENSTGUP00000023270 ENSTGUP00000023270 H1A1Z5_TAEGU H1A1Z5_TAEGU LOC100230026 LOC100230026 NABP1 NABP1 PBK PBK ENSTGUP00000023855 ENSTGUP00000023855 CDC16 CDC16 SPDL1 SPDL1 XPC XPC BRCC3 BRCC3 ZNF830 ZNF830 CCND3 CCND3 MAP3K20 MAP3K20 LRRC1 LRRC1 ENSTGUP00000033975 ENSTGUP00000033975 ENSTGUP00000034670 ENSTGUP00000034670 BUB1B BUB1B LCMT1 LCMT1 RPRML RPRML PINX1 PINX1 CDKN1C CDKN1C STIL STIL LGMN LGMN FOXG1 FOXG1 ENSTGUP00000025305 ENSTGUP00000025305 LOC100223668 LOC100223668 ANGEL1 ANGEL1 FZR1 FZR1 BRINP3 BRINP3 UBE2C UBE2C MNAT1 MNAT1 BTG2 BTG2 CTDSPL CTDSPL LRP5 LRP5 NABP2 NABP2 RAD51B RAD51B INO80 INO80 JADE1 JADE1 DUSP3 DUSP3 CDK7 CDK7 ERCC2 ERCC2 H0Z6S8_TAEGU H0Z6S8_TAEGU ENSTGUP00000026997 ENSTGUP00000026997 LOC100231082-2 LOC100231082-2 RCC2 RCC2 RPA3 RPA3 NDC80 NDC80 H0YTV7_TAEGU H0YTV7_TAEGU CRADD CRADD RFWD3 RFWD3 CDCA2 CDCA2 CCND2 CCND2 LSM11 LSM11 MFSD11 MFSD11 ENSTGUP00000028596 ENSTGUP00000028596 MRNIP MRNIP GBF1 GBF1 HASPIN HASPIN CUL9 CUL9 APP APP EREG EREG FHL1 FHL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EME1ERCC4 domain-containing protein. (545 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (163 aa)
H1A086_TAEGUHA2 domain-containing protein. (1046 aa)
MUC1Uncharacterized protein. (397 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
TFAP4Transcription factor AP-4. (385 aa)
PPP1R10-2Serine/threonine-protein phosphatase 1 regulatory subunit 10. (898 aa)
ENSTGUP00000031243annotation not available (686 aa)
MAD2L1BPMAD2L1 binding protein. (381 aa)
ENSTGUP00000031407annotation not available (277 aa)
LOC100222344Uncharacterized protein. (309 aa)
ENSTGUP00000031587annotation not available (323 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (840 aa)
CDK5RAP2Cnn_1N domain-containing protein. (2275 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (1179 aa)
WACWW domain containing adaptor with coiled-coil. (645 aa)
AVENApoptosis and caspase activation inhibitor. (353 aa)
PSMG2Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (344 aa)
SRSF3Uncharacterized protein. (242 aa)
SDE2SDE2 telomere maintenance homolog. (451 aa)
LOC115494026Ubiquitin carboxyl-terminal hydrolase CYLD isoform X1. (786 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (902 aa)
GIGYF2GYF domain-containing protein. (1277 aa)
LOC115493600Uncharacterized protein. (849 aa)
BTG1BTG anti-proliferation factor 1. (180 aa)
LOC115498196Protransforming growth factor alpha-like. (316 aa)
C10orf90ALMS_motif domain-containing protein. (728 aa)
CACNB4SH3 domain-containing protein. (478 aa)
DCUN1D3DCN1-like protein. (304 aa)
CDC42Cell division cycle 42. (302 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (841 aa)
DYNLT3Dynein light chain Tctex-type 3. (112 aa)
NOP53Ribosome biogenesis protein NOP53-like. (461 aa)
STOX1Stork_head domain-containing protein. (850 aa)
PLRG1WD_REPEATS_REGION domain-containing protein. (669 aa)
ENSTGUP00000037304annotation not available (89 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (656 aa)
ENSTGUP00000037836annotation not available (119 aa)
PLK1Polo like kinase 1. (933 aa)
ANXA1Annexin. (364 aa)
RAD50Zinc-hook domain-containing protein. (1312 aa)
LOC115490804BRISC and BRCA1-A complex member 1-like. (434 aa)
H0ZR88_TAEGUUncharacterized protein. (743 aa)
CDKN1BPutative cyclin-dependent kinase inhibitor 1B. (198 aa)
ATMNon-specific serine/threonine protein kinase. (2226 aa)
TTKProtein kinase domain-containing protein. (863 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (284 aa)
BORABORA aurora kinase A activator. (601 aa)
MTBPMDM2 binding protein. (1041 aa)
RB1RB transcriptional corepressor 1. (931 aa)
INTS13Integrator complex subunit 13. (932 aa)
RRM2BRibonucleotide reductase regulatory TP53 inducible subunit M2B. (347 aa)
FBXO43F-box protein 43. (670 aa)
TTLL12Tubulin tyrosine ligase like 12. (627 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (756 aa)
BRCA2BRCA2 DNA repair associated. (3359 aa)
BUB3BUB3 mitotic checkpoint protein. (329 aa)
MTRF1LF-box protein 5. (592 aa)
APPL2Uncharacterized protein. (658 aa)
HECAHdc homolog, cell cycle regulator. (128 aa)
FBXO7F-box protein 7. (527 aa)
PRKDCUncharacterized protein; Belongs to the PI3/PI4-kinase family. (4133 aa)
ZFYVE19Zinc finger FYVE-type containing 19. (422 aa)
LOC100229685Uncharacterized protein. (183 aa)
KLHL22BTB domain-containing protein. (638 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
PIDD1P53-induced death domain protein 1. (894 aa)
ZWILCHZwilch kinetochore protein. (595 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (1029 aa)
ADAM17ADAM metallopeptidase domain 17. (918 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (397 aa)
DLGAP5DLG associated protein 5. (837 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (935 aa)
CASP2Uncharacterized protein; Belongs to the peptidase C14A family. (426 aa)
FZD3Frizzled domain-containing protein. (696 aa)
LOC100230026-2HA2 domain-containing protein. (1245 aa)
VPS4AAAA domain-containing protein. (446 aa)
LOC100222335EGF-like domain-containing protein. (158 aa)
E4F1E4F transcription factor 1. (777 aa)
USP47USP domain-containing protein; Belongs to the peptidase C19 family. (1447 aa)
ECDEcdysoneless cell cycle regulator. (636 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (799 aa)
CDK5RAP3Uncharacterized protein. (477 aa)
INTS3Integrator complex subunit 3. (1022 aa)
BRINP2BMP/retinoic acid inducible neural specific 2. (788 aa)
RAD17RAD17 checkpoint clamp loader component. (944 aa)
NME6Nucleoside diphosphate kinase. (262 aa)
MIIPUncharacterized protein. (467 aa)
SCRIBScribble planar cell polarity protein. (1623 aa)
RPRMProtein reprimo isoform X1. (105 aa)
SYF2Pre-mRNA-splicing factor SYF2. (320 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1299 aa)
FOXN3Forkhead box N3. (497 aa)
CTDSP1Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1. (258 aa)
GPR132G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (278 aa)
LOC100223123Protein kinase domain-containing protein. (769 aa)
CTC1Uncharacterized protein. (1000 aa)
FBXO31F-box protein 31. (568 aa)
TOM1L1Target of myb1 like 1 membrane trafficking protein. (503 aa)
ANGEL2Angel homolog 2. (672 aa)
MKI67Uncharacterized protein. (2625 aa)
FOXO4Forkhead box O4. (532 aa)
ENSTGUP00000021498annotation not available (382 aa)
ENSTGUP00000021519annotation not available (333 aa)
PPP1R10Protein phosphatase 1 regulatory subunit 10. (866 aa)
CKS1BCyclin-dependent kinase regulatory subunit CKS1. (79 aa)
BABAM2BRISC and BRCA1 A complex member 2. (493 aa)
CDC73Cell division cycle 73. (531 aa)
ANAPC15Uncharacterized protein. (121 aa)
XRCC3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (347 aa)
ENSTGUP00000032655annotation not available (422 aa)
RAD9ACell cycle checkpoint control protein RAD9A. (387 aa)
LOC100226358Uncharacterized protein. (196 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (716 aa)
TIPINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (536 aa)
TFDP1Transcription factor. (412 aa)
TAOK3TAO kinase 3. (908 aa)
CUL4ACullin 4A; Belongs to the cullin family. (936 aa)
PCID2PCI domain containing 2. (400 aa)
PMS2PMS1 homolog 2, mismatch repair system component. (870 aa)
CHFRCheckpoint with forkhead and ring finger domains. (715 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (723 aa)
PTPN3Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (975 aa)
TICRRTreslin_N domain-containing protein. (1957 aa)
CUL3Cullin 3; Belongs to the cullin family. (768 aa)
CDK10Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (381 aa)
CHEK2Checkpoint kinase 2. (532 aa)
TTC28Tetratricopeptide repeat domain 28. (2427 aa)
CDT1Chromatin licensing and DNA replication factor 1. (597 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (953 aa)
E2F7E2F transcription factor 7. (900 aa)
RBL2RB transcriptional corepressor like 2. (1126 aa)
RAD51CRECA_2 domain-containing protein. (367 aa)
TEX14Uncharacterized protein. (1462 aa)
BUB1Uncharacterized protein. (1092 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
NLE1Notchless homolog 1. (509 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (284 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (660 aa)
FANCD2FA complementation group D2. (1445 aa)
RAD9BRAD9 checkpoint clamp component B. (417 aa)
KNTC1Kinetochore associated 1. (2111 aa)
TAOK1TAO kinase 1. (1000 aa)
CDC25BRhodanese domain-containing protein. (319 aa)
CDC7Cell division cycle 7. (584 aa)
BCL7ABAF chromatin remodeling complex subunit BCL7A. (210 aa)
LOC115495410Glycine N-acyltransferase-like protein 3. (282 aa)
ANAPC5ANAPC5 domain-containing protein. (756 aa)
POLDIP2ApaG domain-containing protein. (418 aa)
BIRC5Baculoviral IAP repeat containing 5. (140 aa)
EDN1Endothelin 1. (202 aa)
ANAPC7Anaphase promoting complex subunit 7. (565 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1262 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (936 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (239 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (292 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (393 aa)
TTLTubulin tyrosine ligase. (378 aa)
CDC14ACell division cycle 14A. (609 aa)
CRLF3Cytokine receptor like factor 3. (442 aa)
ATAD5ATPase family AAA domain containing 5. (1827 aa)
ZNF207Zinc finger protein 207. (496 aa)
CTNNB1Catenin beta 1. (781 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (117 aa)
H0Z332_TAEGUCullin_Nedd8 domain-containing protein. (1584 aa)
TOPBP1Uncharacterized protein. (1520 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1635 aa)
NEK11NIMA related kinase 11. (597 aa)
PIM3Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (322 aa)
LOC100224554Uncharacterized protein. (1418 aa)
TPRTPR_MLP1_2 domain-containing protein. (2313 aa)
CUL4BCULLIN_2 domain-containing protein; Belongs to the cullin family. (888 aa)
SIRT1Sirtuin 1. (750 aa)
IL1BInterleukin-1; Belongs to the IL-1 family. (299 aa)
BRINP1BMP/retinoic acid inducible neural specific 1. (816 aa)
RBL1RB transcriptional corepressor like 1. (977 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (730 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1358 aa)
RINT1Uncharacterized protein. (638 aa)
KMT2ELysine methyltransferase 2E. (1852 aa)
CENPFCENP-F_N domain-containing protein. (2954 aa)
BRCA1Uncharacterized protein. (1803 aa)
PSME3Proteasome activator subunit 3. (254 aa)
LOC100231082Uncharacterized protein. (873 aa)
H0YW59_TAEGUUncharacterized protein. (246 aa)
FBXW5F-box and WD repeat domain containing 5. (584 aa)
CDC6Cell division cycle 6. (558 aa)
PKD2Uncharacterized protein. (903 aa)
ABRAXAS1Abraxas 1, BRCA1 A complex subunit. (405 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (441 aa)
MEIOCMeiosis specific with coiled-coil domain. (964 aa)
CDC27Cell division cycle 27. (839 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (208 aa)
INHBAInhibin subunit beta A. (559 aa)
BTCBetacellulin. (163 aa)
ASNSAsparagine synthetase [glutamine-hydrolyzing]. (561 aa)
CLSPNUncharacterized protein. (1423 aa)
ANKRD17Ankyrin repeat domain 17. (2488 aa)
LOC100218902ANK_REP_REGION domain-containing protein. (294 aa)
H0YTF5_TAEGUANK_REP_REGION domain-containing protein. (133 aa)
INIPSOSS complex subunit C; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) (By similarity). (104 aa)
RIOK2RIO kinase 2. (555 aa)
CCNHCyclin H; Belongs to the cyclin family. (306 aa)
RCC1Uncharacterized protein. (445 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
GAS1Uncharacterized protein. (159 aa)
GMNNGeminin DNA replication inhibitor. (228 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (167 aa)
MEPCEMethylphosphate capping enzyme. (547 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4230 aa)
CDC14BUncharacterized protein. (568 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (469 aa)
LOC115497664Ribonucleoside-diphosphate reductase large subunit. (801 aa)
UIMC1Ubiquitin interaction motif containing 1. (813 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
BTG4BTG anti-proliferation factor 4. (229 aa)
ZW10Zw10 kinetochore protein. (782 aa)
KLHL18Kelch like family member 18. (651 aa)
CDC23Cell division cycle 23. (585 aa)
CDC25ACell division cycle 25A. (532 aa)
LSM10Sm domain-containing protein. (123 aa)
ENSTGUP00000023270annotation not available (573 aa)
H1A1Z5_TAEGUUncharacterized protein. (761 aa)
LOC100230026Uncharacterized protein. (1326 aa)
NABP1Nucleic acid binding protein 1. (207 aa)
PBKLymphokine-activated killer T-cell-originated protein kinase. (687 aa)
ENSTGUP00000023855annotation not available (1612 aa)
CDC16Cell division cycle 16. (589 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (624 aa)
XPCUncharacterized protein. (865 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (261 aa)
ZNF830Zinc finger protein 830. (431 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (333 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (476 aa)
LRRC1Leucine rich repeat containing 1. (795 aa)
ENSTGUP00000033975annotation not available (497 aa)
ENSTGUP00000034670annotation not available (523 aa)
BUB1BUncharacterized protein. (1065 aa)
LCMT1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (339 aa)
RPRMLReprimo like. (189 aa)
PINX1PIN2 (TERF1) interacting telomerase inhibitor 1. (359 aa)
CDKN1CCyclin-dependent kinase inhibitor 1C isoform X1. (181 aa)
STILUncharacterized protein. (1346 aa)
LGMNUncharacterized protein. (431 aa)
FOXG1Forkhead box protein G1. (459 aa)
ENSTGUP00000025305annotation not available (534 aa)
LOC100223668G2/mitotic-specific cyclin-B3. (521 aa)
ANGEL1Angel homolog 1. (674 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
BRINP3BMP/retinoic acid inducible neural specific 3. (860 aa)
UBE2CUbiquitin-conjugating enzyme E2 C. (179 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (334 aa)
BTG2Protein Tob/BTG. (172 aa)
CTDSPLFCP1 homology domain-containing protein. (338 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1595 aa)
NABP2SOSS complex subunit B1. (320 aa)
RAD51BRAD51 paralog B. (400 aa)
INO80INO80 complex ATPase subunit. (1558 aa)
JADE1Uncharacterized protein. (859 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (350 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (576 aa)
H0Z6S8_TAEGUGly_acyl_tr_N domain-containing protein. (294 aa)
ENSTGUP00000026997annotation not available (687 aa)
LOC100231082-2Discoidin domain-containing receptor 2-like. (873 aa)
RCC2Protein RCC2. (1203 aa)
RPA3Uncharacterized protein. (244 aa)
NDC80NDC80 kinetochore complex component. (640 aa)
H0YTV7_TAEGUANK_REP_REGION domain-containing protein. (2496 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (248 aa)
RFWD3Ring finger and WD repeat domain 3. (750 aa)
CDCA2PP1-binding domain-containing protein. (990 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (309 aa)
LSM11LSM11, U7 small nuclear RNA associated. (366 aa)
MFSD11Major facilitator superfamily domain containing 11. (449 aa)
ENSTGUP00000028596annotation not available (620 aa)
MRNIPMRN complex-interacting protein. (357 aa)
GBF1Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1965 aa)
HASPINSerine/threonine-protein kinase haspin. (891 aa)
CUL9Cul7 domain-containing protein. (2520 aa)
APPAmyloid beta precursor protein. (797 aa)
EREGEpiregulin. (167 aa)
FHL1Four and a half LIM domains 1. (324 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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