STRINGSTRING
AK5 AK5 H1A122_TAEGU H1A122_TAEGU DGUOK DGUOK AK8 AK8 ENSTGUP00000033671 ENSTGUP00000033671 LRGUK LRGUK IMPDH2 IMPDH2 NT5M NT5M AK6 AK6 LOC100229613 LOC100229613 ENSTGUP00000031301 ENSTGUP00000031301 CDA CDA NT5E NT5E ENSTGUP00000029939 ENSTGUP00000029939 UPP2 UPP2 TYMP TYMP GART GART DTYMK DTYMK AK3 AK3 AMPD2 AMPD2 RFK RFK CMPK2 CMPK2 LOC115496245 LOC115496245 NT5DC1 NT5DC1 LOC100218564 LOC100218564 IMPDH1 IMPDH1 ADK ADK UCK1 UCK1 PAICS PAICS UPP1 UPP1 AK7 AK7 PRPS2 PRPS2 AK2 AK2 LOC100220427 LOC100220427 DCTD DCTD DUT DUT PRTFDC1 PRTFDC1 NUDT2 NUDT2 ADSS1 ADSS1 AK9 AK9 GMPS GMPS NT5C2 NT5C2 TYMS TYMS ADSL ADSL UPB1 UPB1 LOC100220316 LOC100220316 TK2 TK2 H0ZFS5_TAEGU H0ZFS5_TAEGU CMPK1 CMPK1 ADSS2 ADSS2 DHODH DHODH AMPD3 AMPD3 APRT APRT PPAT PPAT UCKL1 UCKL1 LOC100228162 LOC100228162 UPRT UPRT DPYD DPYD NT5C3A NT5C3A ADA ADA UMPS UMPS NT5DC4 NT5DC4 TK1 TK1 ATIC ATIC HPRT1 HPRT1 DCK DCK NT5C1A NT5C1A AMPD1 AMPD1 GDA GDA H0YQC2_TAEGU H0YQC2_TAEGU GUK1 GUK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AK5Uncharacterized protein; Belongs to the adenylate kinase family. (566 aa)
H1A122_TAEGUUncharacterized protein. (1371 aa)
DGUOKdNK domain-containing protein. (439 aa)
AK8Uncharacterized protein; Belongs to the adenylate kinase family. (482 aa)
ENSTGUP00000033671annotation not available (1331 aa)
LRGUKLeucine rich repeats and guanylate kinase domain containing. (764 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (538 aa)
NT5MUncharacterized protein. (232 aa)
AK6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (171 aa)
LOC100229613Uncharacterized protein. (373 aa)
ENSTGUP00000031301annotation not available (200 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (152 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (578 aa)
ENSTGUP00000029939annotation not available (387 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (342 aa)
TYMPThymidine phosphorylase. (462 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1050 aa)
DTYMKDeoxythymidylate kinase. (230 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (225 aa)
AMPD2Uncharacterized protein. (819 aa)
RFKRiboflavin kinase. (155 aa)
CMPK2Cytidine/uridine monophosphate kinase 2. (56 aa)
LOC115496245GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (251 aa)
NT5DC15'-nucleotidase domain containing 1. (541 aa)
LOC100218564PRK domain-containing protein. (572 aa)
IMPDH1Inosine monophosphate dehydrogenase 1. (552 aa)
ADKAdenosine kinase. (448 aa)
UCK1Uridine-cytidine kinase; Belongs to the uridine kinase family. (214 aa)
PAICSAIRC domain-containing protein. (1072 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (351 aa)
AK7Uncharacterized protein. (726 aa)
PRPS2Phosphoribosyl pyrophosphate synthetase 2. (325 aa)
AK2Adenylate kinase 2; Belongs to the adenylate kinase family. (246 aa)
LOC100220427dNK domain-containing protein. (270 aa)
DCTDdCMP deaminase. (380 aa)
DUTDeoxyuridine triphosphatase. (166 aa)
PRTFDC1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (224 aa)
NUDT2Nudix hydrolase 2. (148 aa)
ADSS1Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (454 aa)
AK9Uncharacterized protein. (1514 aa)
GMPSGuanine monophosphate synthase. (693 aa)
NT5C2Uncharacterized protein. (592 aa)
TYMSThymidylat_synt domain-containing protein. (343 aa)
ADSLAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (559 aa)
UPB1Beta-ureidopropionase 1. (466 aa)
LOC100220316Adenylate kinase 4, mitochondrial. (244 aa)
TK2Thymidine kinase 2. (410 aa)
H0ZFS5_TAEGUUncharacterized protein. (124 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (224 aa)
ADSS2Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (463 aa)
DHODHDHO_dh domain-containing protein. (392 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (792 aa)
APRTAdenine phosphoribosyltransferase. (177 aa)
PPATAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (508 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (526 aa)
LOC100228162Pribosyltran_N domain-containing protein. (450 aa)
UPRTUracil phosphoribosyltransferase homolog. (277 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1017 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa)
ADAAdenosine deaminase. (359 aa)
UMPSUridine monophosphate synthetase. (481 aa)
NT5DC45'-nucleotidase domain containing 4. (532 aa)
TK1Thymidine kinase. (223 aa)
ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (593 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
DCKdNK domain-containing protein. (257 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (350 aa)
AMPD1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (742 aa)
GDAGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (493 aa)
H0YQC2_TAEGUTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1038 aa)
GUK1Guanylate kinase 1. (388 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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