96 items (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	METRN	Meteorin. (561 aa)
	FGF5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
	NCMAP	Non-compact myelin associated protein. (276 aa)
	PTPRZ1	Protein tyrosine phosphatase receptor type Z1. (1475 aa)
	ROR1	Inactive tyrosine-protein kinase transmembrane receptor ROR1-like. (940 aa)
	DUSP10	Dual specificity phosphatase 10. (481 aa)
	SOX10	SRY-box transcription factor 10. (591 aa)
	TTC21B	Tetratricopeptide repeat domain 21B. (1283 aa)
	ILK	Integrin linked kinase. (676 aa)
	LEF1	Lymphoid enhancer binding factor 1. (412 aa)
	CDK5	Cyclin-dependent-like kinase 5. (808 aa)
	ARHGEF10	Rho guanine nucleotide exchange factor 10. (1353 aa)
	LOC101233749-2	Oligodendrocyte transcription factor 2. (296 aa)
	ROR2	Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (938 aa)
	APP	Amyloid beta precursor protein. (797 aa)
	ENSTGUP00000028940	annotation not available (219 aa)
	PLP1	Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin; Belongs to the myelin proteolipid protein family. (277 aa)
	SH3TC2	SH3 domain and tetratricopeptide repeats 2. (1514 aa)
	IFNGR1	Fibronectin type-III domain-containing protein. (434 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	LOC100219522	NAD-dependent protein deacetylase sirtuin-2-like. (455 aa)
	LOC101233749	Class B basic helix-loop-helix protein 1/6/7. (296 aa)
	TENM4	Teneurin transmembrane protein 4. (2719 aa)
	ERCC2	ERCC excision repair 2, TFIIH core complex helicase subunit. (576 aa)
	METTL3	Methyltransferase like 3. (449 aa)
	SOX8	SRY-box transcription factor 8. (470 aa)
	ABL1	Tyrosine-protein kinase. (1139 aa)
	ADAM22	ADAM metallopeptidase domain 22. (773 aa)
	B4GALT6	Beta-1,4-galactosyltransferase 6. (355 aa)
	TSPAN2	Tetraspanin. (223 aa)
	WASF3	WASP family member 3. (498 aa)
	LYN	Tyrosine-protein kinase. (605 aa)
	DLX2	Distal-less homeobox 2. (341 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (912 aa)
	CDKN2C	Cyclin dependent kinase inhibitor 2C. (167 aa)
	PRDM8	SET domain-containing protein. (931 aa)
	METTL14	Uncharacterized protein; Belongs to the MT-A70-like family. (507 aa)
	NAB2	NGFI-A-binding protein 2 isoform X1. (488 aa)
	PARD3	Par-3 family cell polarity regulator. (1350 aa)
	MAG	Myelin associated glycoprotein. (541 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (425 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (778 aa)
	NKX6-1	NK6 homeobox 1. (341 aa)
	CNP	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family. (419 aa)
	RELN	Reelin. (3447 aa)
	SOX9	SRY-box transcription factor 9. (474 aa)
	SOX13	SRY-box transcription factor 13. (555 aa)
	EOMES	Eomesodermin. (408 aa)
	MMP24	Matrix metallopeptidase 24. (711 aa)
	GPR157	G protein-coupled receptor 157. (584 aa)
	CRB1	Uncharacterized protein. (1407 aa)
	NCSTN	Nicastrin. (879 aa)
	EIF2B4	Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (728 aa)
	GCM1	Glial cells missing transcription factor 1. (384 aa)
	EIF2B2	Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (363 aa)
	LOC115493455	a_DG1_N2 domain-containing protein. (579 aa)
	NKX6-2	NK6 homeobox 2. (278 aa)
	OLIG3	Oligodendrocyte transcription factor 3. (273 aa)
	MDK	Midkine. (139 aa)
	SH3TC1	Uncharacterized protein. (1331 aa)
	EIF2B5	Eukaryotic translation initiation factor 2B subunit epsilon. (707 aa)
	ROR1-2	Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (940 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (727 aa)
	PLPP3	acidPPc domain-containing protein. (313 aa)
	LAMB2	Uncharacterized protein. (1642 aa)
	B4GALT5	Beta-1,4-galactosyltransferase 5. (393 aa)
	PHOX2B	Paired like homeobox 2B. (294 aa)
	ITGB4	Integrin beta. (1793 aa)
	DLX1	Distal-less homeobox 1. (245 aa)
	DNER	Delta/notch like EGF repeat containing. (723 aa)
	ZNF488	Zinc finger protein 488. (541 aa)
	EIF2B3	Eukaryotic translation initiation factor 2B subunit gamma. (452 aa)
	GPR17	G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family. (343 aa)
	NKX2-2	NK2 homeobox 2. (272 aa)
	CNTF	Ciliary neurotrophic factor. (195 aa)
	ASPA	Uncharacterized protein. (315 aa)
	TPPP	Tubulin polymerization promoting protein. (223 aa)
	FA2H	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (401 aa)
	VTN	SMB domain-containing protein. (452 aa)
	NRROS	Negative regulator of reactive oxygen species. (688 aa)
	LOC100221700	WH2 domain-containing protein. (504 aa)
	EIF2B1	Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (302 aa)
	DAG1	Dystroglycan 1. (896 aa)
	SUZ12	SUZ12 polycomb repressive complex 2 subunit. (874 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	NFIB	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (569 aa)
	PHGDH	Uncharacterized protein. (530 aa)
	CSPG5	Chondroitin sulfate proteoglycan 5 isoform X1. (528 aa)
	ABL2	Tyrosine-protein kinase. (1160 aa)
	NDRG1	N-myc downstream regulated 1. (402 aa)
	ENSTGUP00000018634	annotation not available (359 aa)
	PPP3R1	Uncharacterized protein. (167 aa)
	C1QA	Complement C1q A chain. (242 aa)
	PICK1	Uncharacterized protein. (435 aa)
	MPP5	Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
	MYOC	Myocilin. (521 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	ABL2	ENSTGUP00000026063	ENSTGUP00000018887	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.902
ABL1	CDH2	ENSTGUP00000026063	ENSTGUP00000023877	Tyrosine-protein kinase.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.412
ABL1	CDK5	ENSTGUP00000026063	ENSTGUP00000030783	Tyrosine-protein kinase.	Cyclin-dependent-like kinase 5.	0.463
ABL1	CTNNB1	ENSTGUP00000026063	ENSTGUP00000004945	Tyrosine-protein kinase.	Catenin beta 1.	0.622
ABL1	LOC100221700	ENSTGUP00000026063	ENSTGUP00000005942	Tyrosine-protein kinase.	WH2 domain-containing protein.	0.406
ABL1	WASF3	ENSTGUP00000026063	ENSTGUP00000025136	Tyrosine-protein kinase.	WASP family member 3.	0.406
ABL2	ABL1	ENSTGUP00000018887	ENSTGUP00000026063	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.902
ABL2	CDH2	ENSTGUP00000018887	ENSTGUP00000023877	Tyrosine-protein kinase.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.412
ABL2	CDK5	ENSTGUP00000018887	ENSTGUP00000030783	Tyrosine-protein kinase.	Cyclin-dependent-like kinase 5.	0.463
ABL2	CTNNB1	ENSTGUP00000018887	ENSTGUP00000004945	Tyrosine-protein kinase.	Catenin beta 1.	0.622
ABL2	LOC100221700	ENSTGUP00000018887	ENSTGUP00000005942	Tyrosine-protein kinase.	WH2 domain-containing protein.	0.406
ABL2	WASF3	ENSTGUP00000018887	ENSTGUP00000025136	Tyrosine-protein kinase.	WASP family member 3.	0.406
APP	CDK5	ENSTGUP00000029357	ENSTGUP00000030783	Amyloid beta precursor protein.	Cyclin-dependent-like kinase 5.	0.504
APP	CTNNB1	ENSTGUP00000029357	ENSTGUP00000004945	Amyloid beta precursor protein.	Catenin beta 1.	0.452
APP	MAG	ENSTGUP00000029357	ENSTGUP00000020377	Amyloid beta precursor protein.	Myelin associated glycoprotein.	0.452
APP	NCSTN	ENSTGUP00000029357	ENSTGUP00000004510	Amyloid beta precursor protein.	Nicastrin.	0.942
APP	PSEN1	ENSTGUP00000029357	ENSTGUP00000027530	Amyloid beta precursor protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.962
APP	RELN	ENSTGUP00000029357	ENSTGUP00000002962	Amyloid beta precursor protein.	Reelin.	0.457
APP	SHH	ENSTGUP00000029357	ENSTGUP00000000707	Amyloid beta precursor protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.478
ARHGEF10	NDRG1	ENSTGUP00000030395	ENSTGUP00000018711	Rho guanine nucleotide exchange factor 10.	N-myc downstream regulated 1.	0.428