STRINGSTRING
TNFRSF11B TNFRSF11B SLC30A8 SLC30A8 FGF23 FGF23 ATP7B ATP7B RYR3 RYR3 ALOX5AP ALOX5AP THBS1 THBS1 SYT10 SYT10 UROS UROS SUCNR1 SUCNR1 EIF2AK3 EIF2AK3 ECT2 ECT2 CACNG2 CACNG2 CAV3 CAV3 ATF4 ATF4 CARF CARF PRKAA2 PRKAA2 SYT17 SYT17 SYT8 SYT8 ENSTGUP00000033290 ENSTGUP00000033290 ENSTGUP00000033044 ENSTGUP00000033044 PEF1 PEF1 KHK KHK CUTA-2 CUTA-2 CAPN3 CAPN3 CACNA1G CACNA1G ENSTGUP00000026052 ENSTGUP00000026052 ITPKA ITPKA ENSTGUP00000026711 ENSTGUP00000026711 ENSTGUP00000026997 ENSTGUP00000026997 ALG2 ALG2 ENSTGUP00000027369 ENSTGUP00000027369 CPNE9 CPNE9 SYT1 SYT1 SLC30A4 SLC30A4 ADCY1 ADCY1 KCNMB4 KCNMB4 CACNA1H CACNA1H SMPD3 SMPD3 SYT7 SYT7 MT4 MT4 LOC100190731 LOC100190731 GPLD1 GPLD1 HVCN1 HVCN1 ANXA11 ANXA11 PCSK1 PCSK1 ATP7A ATP7A P2RX4 P2RX4 GSK3B GSK3B GCLC GCLC STIM1 STIM1 BNIP3 BNIP3 CREM CREM LOC105758760 LOC105758760 MEF2A MEF2A ENSTGUP00000019696 ENSTGUP00000019696 KCNMB2 KCNMB2 SYT13 SYT13 SLC25A12 SLC25A12 BMP6 BMP6 TAT TAT ENSTGUP00000019057 ENSTGUP00000019057 FXN FXN MMP9 MMP9 ABCC8 ABCC8 ACER1 ACER1 SYT11 SYT11 CASP9 CASP9 CPOX CPOX LONP1 LONP1 BSG BSG PAM PAM SLC30A1 SLC30A1 CPNE4 CPNE4 LOC115493197 LOC115493197 RASAL1 RASAL1 SMPD1 SMPD1 ENSTGUP00000035105 ENSTGUP00000035105 SYT4 SYT4 SUMO1 SUMO1 ENSTGUP00000036039 ENSTGUP00000036039 ADGRV1 ADGRV1 ENSTGUP00000036312 ENSTGUP00000036312 CLDN1 CLDN1 MEF2C MEF2C SYT6 SYT6 NFE2L2 NFE2L2 SLC25A13 SLC25A13 SLC30A10 SLC30A10 SLC30A2 SLC30A2 CLIC4 CLIC4 SYT2 SYT2 LOC115492493 LOC115492493 MTF1 MTF1 ACO1 ACO1 CD14 CD14 PKD2 PKD2 SLC26A5 SLC26A5 HAAO HAAO NCF1 NCF1 CRHBP CRHBP SLC6A1 SLC6A1 GSS GSS ITPKB ITPKB NCSTN NCSTN CACNG4 CACNG4 CER1 CER1 ENTPD6 ENTPD6 SYT9 SYT9 CPNE2 CPNE2 FGG FGG ADAMTS13 ADAMTS13 FIBIN FIBIN ABCB6 ABCB6 LOC100226015 LOC100226015 D2HGDH D2HGDH TRPM2 TRPM2 SLC30A3 SLC30A3 CAV1 CAV1 RYR2 RYR2 ENSTGUP00000028260 ENSTGUP00000028260 SYT3 SYT3 SLC40A1 SLC40A1 STIM1-2 STIM1-2 ENSTGUP00000029110 ENSTGUP00000029110 FOS FOS SYT12 SYT12 PDCD6 PDCD6 TRPC1 TRPC1 OGG1 OGG1 TIGAR TIGAR PRKAA1 PRKAA1 AQP1 AQP1 ADCY8 ADCY8 LOC100225533 LOC100225533 CPNE8 CPNE8 LOC100230025 LOC100230025 MNAT1 MNAT1 CRIP1 CRIP1 ENSTGUP00000025068 ENSTGUP00000025068 LGMN LGMN LOC115492493-2 LOC115492493-2 ENSTGUP00000024522 ENSTGUP00000024522 EEF2K EEF2K CUTA CUTA CPNE7 CPNE7 CREB1 CREB1 ENSTGUP00000021421 ENSTGUP00000021421 ADD1 ADD1 ARL13B ARL13B LRRK2 LRRK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (501 aa)
SLC30A8Uncharacterized protein. (320 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (253 aa)
ATP7BUncharacterized protein. (1530 aa)
RYR3Uncharacterized protein. (3017 aa)
ALOX5APArachidonate 5-lipoxygenase activating protein. (161 aa)
THBS1Uncharacterized protein. (1173 aa)
SYT10Synaptotagmin 10. (522 aa)
UROSUroporphyrinogen III synthase. (269 aa)
SUCNR1Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (303 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1087 aa)
ECT2Uncharacterized protein. (985 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ATF4Activating transcription factor 4. (354 aa)
CARFCalcium responsive transcription factor. (711 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
SYT17Synaptotagmin 17. (474 aa)
SYT8Synaptotagmin 8. (393 aa)
ENSTGUP00000033290annotation not available (332 aa)
ENSTGUP00000033044annotation not available (309 aa)
PEF1Penta-EF-hand domain containing 1. (240 aa)
KHKKetohexokinase isoform X1. (303 aa)
CUTA-2Uncharacterized protein. (243 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (809 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2305 aa)
ENSTGUP00000026052Ryanodine receptor 1-like. (3693 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (482 aa)
ENSTGUP00000026711annotation not available (119 aa)
ENSTGUP00000026997annotation not available (687 aa)
ALG2ALG2 alpha-1,3/1,6-mannosyltransferase. (411 aa)
ENSTGUP00000027369annotation not available (253 aa)
CPNE9Copine family member 9. (545 aa)
SYT1Synaptotagmin I. (425 aa)
SLC30A4Solute carrier family 30 member 4. (453 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (211 aa)
CACNA1HVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2284 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (660 aa)
SYT7Synaptotagmin 7. (684 aa)
MT4Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (63 aa)
LOC100190731Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (63 aa)
GPLD1Zn_dep_PLPC domain-containing protein. (834 aa)
HVCN1Hydrogen voltage gated channel 1. (236 aa)
ANXA11Annexin. (522 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (749 aa)
ATP7AATPase copper transporting alpha. (1497 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (400 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (636 aa)
STIM1Stromal interaction molecule 1. (1283 aa)
BNIP3BCL2 interacting protein 3. (275 aa)
CREMcAMP responsive element modulator. (125 aa)
LOC105758760Uncharacterized protein. (1184 aa)
MEF2AMyocyte enhancer factor 2A. (496 aa)
ENSTGUP00000019696annotation not available (133 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (278 aa)
SYT13Synaptotagmin 13. (431 aa)
SLC25A12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (669 aa)
BMP6Bone morphogenetic protein 6. (414 aa)
TATTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (455 aa)
ENSTGUP00000019057annotation not available (506 aa)
FXNFrataxin. (235 aa)
MMP9Matrix metallopeptidase 9. (723 aa)
ABCC8ATP binding cassette subfamily C member 8. (1620 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (263 aa)
SYT11Synaptotagmin 11. (484 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (420 aa)
CPOXUncharacterized protein. (401 aa)
LONP1Uncharacterized protein. (937 aa)
BSGBasigin (Ok blood group). (345 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (914 aa)
SLC30A1Solute carrier family 30 member 1. (655 aa)
CPNE4Copine 4. (578 aa)
LOC115493197Protein fosB isoform X1. (310 aa)
RASAL1RAS protein activator like 1. (956 aa)
SMPD1Uncharacterized protein. (622 aa)
ENSTGUP00000035105annotation not available (630 aa)
SYT4Uncharacterized protein. (571 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
ENSTGUP00000036039annotation not available (290 aa)
ADGRV1Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6252 aa)
ENSTGUP00000036312annotation not available (479 aa)
CLDN1Claudin 1. (213 aa)
MEF2CMyocyte enhancer factor 2C. (244 aa)
SYT6Synaptotagmin 6. (520 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (623 aa)
SLC25A13Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (681 aa)
SLC30A10Solute carrier family 30 member 10. (245 aa)
SLC30A2Uncharacterized protein. (362 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
SYT2Synaptotagmin 2. (415 aa)
LOC115492493Uncharacterized protein. (199 aa)
MTF1Metal regulatory transcription factor 1. (731 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa)
CD14Uncharacterized protein. (450 aa)
PKD2Uncharacterized protein. (903 aa)
SLC26A5STAS domain-containing protein. (740 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa)
NCF1Neutrophil cytosolic factor 1. (386 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (330 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (598 aa)
GSSGlutathione synthetase. (474 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (605 aa)
NCSTNNicastrin. (879 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (328 aa)
CER1Cerberus 1, DAN family BMP antagonist. (273 aa)
ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (442 aa)
SYT9Uncharacterized protein. (519 aa)
CPNE2Copine 2. (544 aa)
FGGFibrinogen gamma chain. (433 aa)
ADAMTS13Peptidase M12B domain-containing protein. (1391 aa)
FIBINFin bud initiation factor homolog. (204 aa)
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (840 aa)
LOC100226015Uncharacterized protein. (536 aa)
D2HGDHD-2-hydroxyglutarate dehydrogenase. (518 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1541 aa)
SLC30A3Solute carrier family 30 member 3. (382 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
RYR2Ryanodine receptor 2. (4939 aa)
ENSTGUP00000028260annotation not available (531 aa)
SYT3Uncharacterized protein. (529 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (577 aa)
STIM1-2Stromal interaction molecule 1 isoform X6. (422 aa)
ENSTGUP00000029110annotation not available (193 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (370 aa)
SYT12Synaptotagmin 12. (472 aa)
PDCD6Programmed cell death 6. (121 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (774 aa)
OGG18-oxoguanine DNA glycosylase. (375 aa)
TIGARUncharacterized protein. (284 aa)
PRKAA1Non-specific serine/threonine protein kinase. (561 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1319 aa)
LOC100225533Uncharacterized protein. (188 aa)
CPNE8Copine 8. (639 aa)
LOC100230025Ras-GAP domain-containing protein. (860 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (334 aa)
CRIP1LIM zinc-binding domain-containing protein. (166 aa)
ENSTGUP00000025068annotation not available (131 aa)
LGMNUncharacterized protein. (431 aa)
LOC115492493-2Guanylyl cyclase-activating protein 1. (199 aa)
ENSTGUP00000024522annotation not available (197 aa)
EEF2KEukaryotic elongation factor 2 kinase. (736 aa)
CUTAcutA divalent cation tolerance homolog. (161 aa)
CPNE7Copine-7. (569 aa)
CREB1cAMP responsive element binding protein 1. (324 aa)
ENSTGUP00000021421annotation not available (1349 aa)
ADD1Adducin 1. (861 aa)
ARL13BADP ribosylation factor like GTPase 13B. (396 aa)
LRRK2Leucine rich repeat kinase 2. (2509 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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