STRINGSTRING
RIN2 RIN2 ANXA1 ANXA1 BCAS3 BCAS3 NFE2L2 NFE2L2 JCAD JCAD ENPP2 ENPP2 ENSTGUP00000033254 ENSTGUP00000033254 TGFB2 TGFB2 CIB1 CIB1 ATP5F1A ATP5F1A KDR KDR CAPN7 CAPN7 ZC3H12A ZC3H12A EPB41L5 EPB41L5 CLASP1 CLASP1 BCAR1 BCAR1 LGMN LGMN FGF2 FGF2 VEGFA VEGFA ENSTGUP00000023034 ENSTGUP00000023034 SASH1 SASH1 LOC100224755 LOC100224755 RAB25 RAB25 PIK3CB PIK3CB ETS1 ETS1 LOC100222362 LOC100222362 ENSTGUP00000020196 ENSTGUP00000020196 PDGFB PDGFB EPB41L4B EPB41L4B ANGPT1 ANGPT1 PIK3CD PIK3CD FGF7 FGF7 LOC115491349 LOC115491349 MMP9 MMP9 P2RX4 P2RX4 FGF18 FGF18 ARF6 ARF6 ROCK2 ROCK2 ADAM17 ADAM17 ITGB1BP1 ITGB1BP1 TSTA3 TSTA3 NUS1 NUS1 THBS1 THBS1 ATOH8 ATOH8 BMPR2 BMPR2 CTSH CTSH AGT AGT MAP4K4 MAP4K4 GPI GPI PLPP3 PLPP3 GLIPR2 GLIPR2 ANGPT4 ANGPT4 GPLD1 GPLD1 VEGFC VEGFC CD40 CD40 VIL1 VIL1 AAMP AAMP MET MET PLCG1 PLCG1 PLCG2 PLCG2 LOC100224677 LOC100224677 TGFBR2 TGFBR2 SIRT1 SIRT1 ITGB3 ITGB3 PIK3CG PIK3CG SOX9 SOX9 MTOR MTOR GATA3 GATA3 MAP3K3 MAP3K3 CCBE1 CCBE1 CLASP2 CLASP2 TEK TEK FLT4 FLT4 BSG BSG LOC100226503 LOC100226503 FGF1 FGF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIN2Ras and Rab interactor 2. (888 aa)
ANXA1Annexin. (364 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (946 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (623 aa)
JCADJunctional cadherin 5 associated. (1330 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (910 aa)
ENSTGUP00000033254annotation not available (279 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (433 aa)
CIB1Calcium and integrin binding 1. (213 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (585 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
CAPN7Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (809 aa)
ZC3H12AC3H1-type domain-containing protein. (609 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (766 aa)
CLASP1Uncharacterized protein. (1555 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (1231 aa)
LGMNUncharacterized protein. (431 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (153 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (394 aa)
ENSTGUP00000023034annotation not available (327 aa)
SASH1SAM and SH3 domain containing 1. (1206 aa)
LOC100224755Transcription factor Sp1-like. (764 aa)
RAB25RAB25, member RAS oncogene family. (291 aa)
PIK3CBUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
ETS1ETS proto-oncogene 1, transcription factor. (552 aa)
LOC100222362Phosphoinositide phospholipase C. (1311 aa)
ENSTGUP000000201961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1. (1281 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (278 aa)
EPB41L4BFERM domain-containing protein. (862 aa)
ANGPT1Angiopoietin 1. (498 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1054 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
LOC115491349Transcription factor Sp1. (764 aa)
MMP9Matrix metallopeptidase 9. (723 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (400 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (142 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1483 aa)
ADAM17ADAM metallopeptidase domain 17. (918 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
TSTA3Uncharacterized protein. (336 aa)
NUS1NUS1 dehydrodolichyl diphosphate synthase subunit. (282 aa)
THBS1Uncharacterized protein. (1173 aa)
ATOH8BHLH domain-containing protein. (330 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1036 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (367 aa)
AGTAngiotensinogen; Belongs to the serpin family. (462 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1385 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (794 aa)
PLPP3acidPPc domain-containing protein. (313 aa)
GLIPR2GLI pathogenesis related 2; Belongs to the CRISP family. (174 aa)
ANGPT4Angiopoietin 4. (501 aa)
GPLD1Zn_dep_PLPC domain-containing protein. (834 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (468 aa)
CD40CD40 molecule. (280 aa)
VIL1Villin 1. (839 aa)
AAMPAngio associated migratory cell protein. (496 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1385 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1282 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1223 aa)
LOC100224677TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (559 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (568 aa)
SIRT1Sirtuin 1. (750 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (797 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1106 aa)
SOX9SRY-box transcription factor 9. (474 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (1322 aa)
GATA3GATA binding protein 3. (443 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (642 aa)
CCBE1Collagen and calcium binding EGF domains 1. (394 aa)
CLASP2Cytoplasmic linker associated protein 2. (1408 aa)
TEKTEK receptor tyrosine kinase. (1117 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1379 aa)
BSGBasigin (Ok blood group). (345 aa)
LOC100226503Uncharacterized protein. (621 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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