(23 nodes) Positive regulation of phosphatase activity network (Taeniopygia guttata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	AGTR2	Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	PPP1R12B-2	Protein phosphatase 1 regulatory subunit 12B. (187 aa)
	IHH	Indian hedgehog signaling molecule. (408 aa)
	MAGI2	Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1334 aa)
	PPARGC1B	PPARG coactivator 1 beta. (988 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (425 aa)
	PDGFRB	Platelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1092 aa)
	LOC100226641	Myotubularin phosphatase domain-containing protein. (586 aa)
	ITGA1	Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1137 aa)
	NPNT	Uncharacterized protein. (531 aa)
	GPLD1	Zn_dep_PLPC domain-containing protein. (834 aa)
	VRK3	VRK serine/threonine kinase 3. (649 aa)
	ROCK1	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1358 aa)
	MTMR9	Myotubularin related protein 9. (551 aa)
	GNA12	G protein subunit alpha 12. (385 aa)
	MAGI2-2	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X1. (136 aa)
	ENSTGUP00000024172	annotation not available (696 aa)
	PPP1R12B	Protein phosphatase 1 regulatory subunit. (910 aa)
	PPP1R15B	PP1c_bdg domain-containing protein. (601 aa)
	PTPA	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (325 aa)
	ACVR1	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (647 aa)
	PTPRC	Uncharacterized protein. (1194 aa)
	PPP1R12A	Protein phosphatase 1 regulatory subunit. (1072 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTGUP00000024172	PPP1R12B-2	ENSTGUP00000024172	ENSTGUP00000032413	annotation not available	Protein phosphatase 1 regulatory subunit 12B.	0.883
ENSTGUP00000024172	ROCK1	ENSTGUP00000024172	ENSTGUP00000010612	annotation not available	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.404
GNA12	ROCK1	ENSTGUP00000018487	ENSTGUP00000010612	G protein subunit alpha 12.	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.457
IHH	SHH	ENSTGUP00000038054	ENSTGUP00000000707	Indian hedgehog signaling molecule.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.910
MAGI2	MAGI2-2	ENSTGUP00000036432	ENSTGUP00000020459	Membrane associated guanylate kinase, WW and PDZ domain containing 2.	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X1.	0.900
MAGI2-2	MAGI2	ENSTGUP00000020459	ENSTGUP00000036432	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X1.	Membrane associated guanylate kinase, WW and PDZ domain containing 2.	0.900
PDGFRB	PTPRC	ENSTGUP00000000985	ENSTGUP00000027581	Platelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Uncharacterized protein.	0.414
PPP1R12A	PPP1R12B	ENSTGUP00000027670	ENSTGUP00000024629	Protein phosphatase 1 regulatory subunit.	Protein phosphatase 1 regulatory subunit.	0.903
PPP1R12A	ROCK1	ENSTGUP00000027670	ENSTGUP00000010612	Protein phosphatase 1 regulatory subunit.	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.937
PPP1R12B	PPP1R12A	ENSTGUP00000024629	ENSTGUP00000027670	Protein phosphatase 1 regulatory subunit.	Protein phosphatase 1 regulatory subunit.	0.903
PPP1R12B	PPP1R12B-2	ENSTGUP00000024629	ENSTGUP00000032413	Protein phosphatase 1 regulatory subunit.	Protein phosphatase 1 regulatory subunit 12B.	0.900
PPP1R12B	ROCK1	ENSTGUP00000024629	ENSTGUP00000010612	Protein phosphatase 1 regulatory subunit.	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.937
PPP1R12B-2	ENSTGUP00000024172	ENSTGUP00000032413	ENSTGUP00000024172	Protein phosphatase 1 regulatory subunit 12B.	annotation not available	0.883
PPP1R12B-2	PPP1R12B	ENSTGUP00000032413	ENSTGUP00000024629	Protein phosphatase 1 regulatory subunit 12B.	Protein phosphatase 1 regulatory subunit.	0.900
PPP1R12B-2	ROCK1	ENSTGUP00000032413	ENSTGUP00000010612	Protein phosphatase 1 regulatory subunit 12B.	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.404
PTPRC	PDGFRB	ENSTGUP00000027581	ENSTGUP00000000985	Uncharacterized protein.	Platelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.414
ROCK1	ENSTGUP00000024172	ENSTGUP00000010612	ENSTGUP00000024172	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	annotation not available	0.404
ROCK1	GNA12	ENSTGUP00000010612	ENSTGUP00000018487	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	G protein subunit alpha 12.	0.457
ROCK1	PPP1R12A	ENSTGUP00000010612	ENSTGUP00000027670	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Protein phosphatase 1 regulatory subunit.	0.937
ROCK1	PPP1R12B	ENSTGUP00000010612	ENSTGUP00000024629	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Protein phosphatase 1 regulatory subunit.	0.937