(12 nodes) Neural crest formation network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GSC	Goosecoid homeobox. (441 aa)
	TCOF1	LisH domain-containing protein. (1033 aa)
	KLHL12	BTB domain-containing protein. (660 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
	SOX9	SRY-box transcription factor 9. (474 aa)
	EDN1	Endothelin 1. (202 aa)
	NOLC1	SRP40_C domain-containing protein. (698 aa)
	PDCD6	Programmed cell death 6. (121 aa)
	KBTBD8	Kelch repeat and BTB domain containing 8. (638 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1612 aa)
	PEF1	Penta-EF-hand domain containing 1. (240 aa)
	POLR1B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1205 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDN1	EDNRA	ENSTGUP00000005994	ENSTGUP00000002706	Endothelin 1.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.999
EDNRA	EDN1	ENSTGUP00000002706	ENSTGUP00000005994	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin 1.	0.999
KBTBD8	KLHL12	ENSTGUP00000009924	ENSTGUP00000001287	Kelch repeat and BTB domain containing 8.	BTB domain-containing protein.	0.641
KBTBD8	NOLC1	ENSTGUP00000009924	ENSTGUP00000007598	Kelch repeat and BTB domain containing 8.	SRP40_C domain-containing protein.	0.587
KBTBD8	PDCD6	ENSTGUP00000009924	ENSTGUP00000008984	Kelch repeat and BTB domain containing 8.	Programmed cell death 6.	0.431
KBTBD8	TCOF1	ENSTGUP00000009924	ENSTGUP00000000888	Kelch repeat and BTB domain containing 8.	LisH domain-containing protein.	0.435
KLHL12	KBTBD8	ENSTGUP00000001287	ENSTGUP00000009924	BTB domain-containing protein.	Kelch repeat and BTB domain containing 8.	0.641
KLHL12	PDCD6	ENSTGUP00000001287	ENSTGUP00000008984	BTB domain-containing protein.	Programmed cell death 6.	0.683
KLHL12	PEF1	ENSTGUP00000001287	ENSTGUP00000033043	BTB domain-containing protein.	Penta-EF-hand domain containing 1.	0.671
NOLC1	KBTBD8	ENSTGUP00000007598	ENSTGUP00000009924	SRP40_C domain-containing protein.	Kelch repeat and BTB domain containing 8.	0.587
NOLC1	POLR1B	ENSTGUP00000007598	ENSTGUP00000035461	SRP40_C domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.837
NOLC1	TCOF1	ENSTGUP00000007598	ENSTGUP00000000888	SRP40_C domain-containing protein.	LisH domain-containing protein.	0.417
PDCD6	KBTBD8	ENSTGUP00000008984	ENSTGUP00000009924	Programmed cell death 6.	Kelch repeat and BTB domain containing 8.	0.431
PDCD6	KLHL12	ENSTGUP00000008984	ENSTGUP00000001287	Programmed cell death 6.	BTB domain-containing protein.	0.683
PEF1	KLHL12	ENSTGUP00000033043	ENSTGUP00000001287	Penta-EF-hand domain containing 1.	BTB domain-containing protein.	0.671
POLR1B	NOLC1	ENSTGUP00000035461	ENSTGUP00000007598	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	SRP40_C domain-containing protein.	0.837
TCOF1	KBTBD8	ENSTGUP00000000888	ENSTGUP00000009924	LisH domain-containing protein.	Kelch repeat and BTB domain containing 8.	0.435
TCOF1	NOLC1	ENSTGUP00000000888	ENSTGUP00000007598	LisH domain-containing protein.	SRP40_C domain-containing protein.	0.417