STRINGSTRING
TLE4 TLE4 BCL9L BCL9L TRABD2A TRABD2A WNT3 WNT3 CSNK1A1 CSNK1A1 DIXDC1 DIXDC1 TLE2 TLE2 LOC100226230 LOC100226230 FZD8 FZD8 APC APC WNT8A WNT8A KLHL12 KLHL12 FZD1 FZD1 RSPO1 RSPO1 WNT9B WNT9B GATA3 GATA3 DAB2 DAB2 PKD2 PKD2 DRAXIN DRAXIN EDNRA EDNRA LOC100226560 LOC100226560 EDA EDA SOX9 SOX9 SOST SOST HBP1 HBP1 DVL1 DVL1 LRRC45 LRRC45 WNT7A WNT7A LOC100230811 LOC100230811 AXIN2 AXIN2 PITX2 PITX2 AXIN1 AXIN1 WWOX WWOX CSNK1G1 CSNK1G1 LGR4 LGR4 CSNK2A2 CSNK2A2 PTK7 PTK7 CTNNB1 CTNNB1 TNKS TNKS WNT2 WNT2 SFRP2 SFRP2 WNT6 WNT6 EDN1 EDN1 CPE CPE AMOTL2 AMOTL2 RECK RECK CSNK2A1 CSNK2A1 RSPO4 RSPO4 WNT5A WNT5A CCDC88A CCDC88A CYLD CYLD WNT8B WNT8B CUL3 CUL3 BRD7 BRD7 SIAH1 SIAH1 NLK NLK INVS INVS SCYL2 SCYL2 H0ZFI9_TAEGU H0ZFI9_TAEGU PLPP3 PLPP3 PRKAA2 PRKAA2 C12orf43 C12orf43 LOC115496685 LOC115496685 APCDD1 APCDD1 ROR1-2 ROR1-2 FZD5 FZD5 DVL3 DVL3 FZD7 FZD7 LOC100225657 LOC100225657 CPZ CPZ CBY1 CBY1 CAV3 CAV3 EPM2A EPM2A RTF1 RTF1 UBAC2 UBAC2 IFT80 IFT80 FRZB FRZB ZRANB1 ZRANB1 RSPO3 RSPO3 FZD6 FZD6 RSPO2 RSPO2 CCDC88C CCDC88C LRP6 LRP6 H0ZR88_TAEGU H0ZR88_TAEGU DACT1 DACT1 FZD3 FZD3 GSK3B GSK3B BCL9 BCL9 WNT11 WNT11 VAX2 VAX2 WNT1 WNT1 NXN NXN DKK3 DKK3 WNT2B WNT2B SOSTDC1 SOSTDC1 PYGO2 PYGO2 LZTS2 LZTS2 WNT3A WNT3A H0YQM1_TAEGU H0YQM1_TAEGU TLE5 TLE5 SFRP4 SFRP4 WNT10A WNT10A TCF7L1 TCF7L1 CELSR1 CELSR1 DISC1 DISC1 NDP NDP LOC115495260 LOC115495260 SDC1 SDC1 MESD MESD HMGXB4 HMGXB4 PKD1 PKD1 LOC100221701 LOC100221701 PYGO1 PYGO1 CSNK1G3 CSNK1G3 LOC115493186 LOC115493186 CSNK1G2 CSNK1G2 LOC100225657-2 LOC100225657-2 ZNRF3 ZNRF3 JUP JUP KREMEN1 KREMEN1 DAAM2 DAAM2 LRP5 LRP5 LOC115493953 LOC115493953 WNT16 WNT16 WNT4 WNT4 WIF1 WIF1 WNT9A WNT9A CAV1 CAV1 SLC9A3R1 SLC9A3R1 CTHRC1 CTHRC1 SIAH2 SIAH2 CELSR3 CELSR3 TCF7L2 TCF7L2 CELSR2 CELSR2 PORCN PORCN DAAM1 DAAM1 WNT7B WNT7B ROR2 ROR2 DKK1 DKK1 LDB1 LDB1 TRABD2B TRABD2B GID8 GID8 LOC115496686 LOC115496686 ENSTGUP00000031580 ENSTGUP00000031580 LEF1 LEF1 LEO1 LEO1 CCDC90B CCDC90B RYK RYK SFRP5 SFRP5 RNF146 RNF146 TLE1 TLE1 ROR1 ROR1 PRKAA1 PRKAA1 USP34 USP34 SFRP1 SFRP1 FZD4 FZD4 CDK14 CDK14 NKD1 NKD1 LOC115494026 LOC115494026 TAX1BP3 TAX1BP3 MYOC MYOC LATS2 LATS2 EDNRB EDNRB ENSTGUP00000037171 ENSTGUP00000037171 GSC GSC WNT5B WNT5B CSNK1D CSNK1D TCF7 TCF7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TLE4TLE family member 4, transcriptional corepressor. (774 aa)
BCL9LBCL9 like. (1508 aa)
TRABD2ATraB domain containing 2A. (513 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
CSNK1A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
DIXDC1DIX domain containing 1. (686 aa)
TLE2TLE family member 2, transcriptional corepressor. (532 aa)
LOC100226230TLE_N domain-containing protein. (771 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (341 aa)
APCAPC regulator of WNT signaling pathway. (2809 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
KLHL12BTB domain-containing protein. (660 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
RSPO1R-spondin 1. (258 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (313 aa)
GATA3GATA binding protein 3. (443 aa)
DAB2DAB adaptor protein 2. (716 aa)
PKD2Uncharacterized protein. (903 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord; Belongs to the draxin family. (348 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
LOC100226560Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (289 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (239 aa)
SOX9SRY-box transcription factor 9. (474 aa)
SOSTSclerostin. (212 aa)
HBP1HMG-box transcription factor 1. (530 aa)
DVL1Uncharacterized protein. (698 aa)
LRRC45Leucine rich repeat containing 45. (750 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
LOC100230811Uncharacterized protein. (285 aa)
AXIN2Axin-2 isoform X1. (829 aa)
PITX2Homeobox protein. (360 aa)
AXIN1Axin 1. (841 aa)
WWOXWW domain containing oxidoreductase. (517 aa)
CSNK1G1Casein kinase 1 gamma 1. (464 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (950 aa)
CSNK2A2Casein kinase 2 alpha 2. (470 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1058 aa)
CTNNB1Catenin beta 1. (781 aa)
TNKSPoly [ADP-ribose] polymerase. (1266 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
SFRP2Secreted frizzled related protein 2. (292 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (442 aa)
EDN1Endothelin 1. (202 aa)
CPECarboxypeptidase E. (436 aa)
AMOTL2Angiomotin like 2. (691 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (963 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (399 aa)
RSPO4R-spondin 4. (223 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (385 aa)
CCDC88ACoiled-coil domain containing 88A. (1904 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (953 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
CUL3Cullin 3; Belongs to the cullin family. (768 aa)
BRD7Bromodomain containing 7. (683 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (524 aa)
INVSInversin. (1107 aa)
SCYL2SCY1 like pseudokinase 2. (932 aa)
H0ZFI9_TAEGUUncharacterized protein. (286 aa)
PLPP3acidPPc domain-containing protein. (313 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
C12orf43Chromosome 12 open reading frame 43. (312 aa)
LOC115496685Transducin-like enhancer protein 3. (767 aa)
APCDD1APC down-regulated 1. (514 aa)
ROR1-2Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (940 aa)
FZD5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (707 aa)
DVL3Dishevelled segment polarity protein 3. (712 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (573 aa)
LOC100225657Wnt ligand secretion mediator. (541 aa)
CPZFZ domain-containing protein. (649 aa)
CBY1Chibby family member 1, beta catenin antagonist. (116 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
EPM2AEPM2A glucan phosphatase, laforin. (319 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (670 aa)
UBAC2UBA domain containing 2. (343 aa)
IFT80Intraflagellar transport 80. (267 aa)
FRZBFrizzled related protein. (379 aa)
ZRANB1Zinc finger RANBP2-type containing 1. (708 aa)
RSPO3R-spondin 3. (275 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (709 aa)
RSPO2Uncharacterized protein. (241 aa)
CCDC88CCalponin-homology (CH) domain-containing protein. (2095 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1612 aa)
H0ZR88_TAEGUUncharacterized protein. (743 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (784 aa)
FZD3Frizzled domain-containing protein. (696 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
BCL9BCL9 domain-containing protein. (1422 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
VAX2Homeobox domain-containing protein. (289 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
NXNThioredoxin domain-containing protein. (421 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (432 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (385 aa)
SOSTDC1Sclerostin domain containing 1. (206 aa)
PYGO2Pygopus family PHD finger 2. (609 aa)
LZTS2Leucine zipper putative tumor suppressor 2. (670 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
H0YQM1_TAEGUTLE_N domain-containing protein. (372 aa)
TLE5TLE family member 5 isoform X1. (197 aa)
SFRP4Secreted frizzled related protein 4. (346 aa)
WNT10AWingless-type MMTV integration site family, member 10. (745 aa)
TCF7L1Transcription factor 7 like 1. (767 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2912 aa)
DISC1DISC1 scaffold protein. (852 aa)
NDPCTCK domain-containing protein. (148 aa)
LOC115495260Endothelin receptor type B-like. (493 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (315 aa)
MESDMesoderm development LRP chaperone. (220 aa)
HMGXB4HMG domain-containing protein 4 isoform X2. (185 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4230 aa)
LOC100221701G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (460 aa)
PYGO1Pygopus family PHD finger 1. (418 aa)
CSNK1G3Protein kinase domain-containing protein. (451 aa)
LOC115493186RNA polymerase II-associated factor 1 homolog. (521 aa)
CSNK1G2Casein kinase 1 gamma 2. (450 aa)
LOC100225657-2Protein wntless homolog. (541 aa)
ZNRF3RING-type domain-containing protein. (979 aa)
JUPJunction plakoglobin. (764 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (390 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1084 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1595 aa)
LOC115493953Frequently rearranged in advanced T-cell lymphomas 2. (205 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (509 aa)
WIF1WNT inhibitory factor 1. (407 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (382 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
SLC9A3R1SLC9A3 regulator 1. (333 aa)
CTHRC1Collagen triple helix repeat containing 1. (468 aa)
SIAH2E3 ubiquitin-protein ligase SIAH2. (309 aa)
CELSR3Cadherin EGF LAG seven-pass G-type receptor 3 isoform X1. (543 aa)
TCF7L2Transcription factor 7 like 2. (600 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2. (2886 aa)
PORCNProtein-serine O-palmitoleoyltransferase porcupine. (522 aa)
DAAM1Dishevelled associated activator of morphogenesis 1. (1079 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (938 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (263 aa)
LDB1LIM domain binding 1. (558 aa)
TRABD2BUncharacterized protein. (524 aa)
GID8GID complex subunit 8 homolog. (228 aa)
LOC115496686Transducin-like enhancer protein 3. (769 aa)
ENSTGUP00000031580annotation not available (272 aa)
LEF1Lymphoid enhancer binding factor 1. (412 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (656 aa)
CCDC90BCoiled-coil domain containing 90B. (265 aa)
RYKReceptor like tyrosine kinase. (696 aa)
SFRP5Secreted frizzled related protein 5. (316 aa)
RNF146Ring finger protein 146. (347 aa)
TLE1TLE family member 1, transcriptional corepressor. (772 aa)
ROR1Inactive tyrosine-protein kinase transmembrane receptor ROR1-like. (940 aa)
PRKAA1Non-specific serine/threonine protein kinase. (561 aa)
USP34Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3513 aa)
SFRP1Secreted frizzled related protein 1. (311 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
CDK14Cyclin dependent kinase 14; Belongs to the protein kinase superfamily. (469 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (477 aa)
LOC115494026Ubiquitin carboxyl-terminal hydrolase CYLD isoform X1. (786 aa)
TAX1BP3Tax1 binding protein 3. (139 aa)
MYOCMyocilin. (521 aa)
LATS2Non-specific serine/threonine protein kinase. (1153 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (428 aa)
ENSTGUP00000037171annotation not available (491 aa)
GSCGoosecoid homeobox. (441 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (796 aa)
CSNK1DCasein kinase 1 delta; Belongs to the protein kinase superfamily. (415 aa)
TCF7Transcription factor 7. (462 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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