(52 nodes) SCF ubiquitin ligase complex network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FBXL22	F-box and leucine rich repeat protein 22. (223 aa)
	FBXO32	F-box protein 32. (355 aa)
	FBXW4	F-box and WD repeat domain containing 4. (408 aa)
	H0Z6S8_TAEGU	Gly_acyl_tr_N domain-containing protein. (294 aa)
	LOC100231198	F-box only protein 42. (634 aa)
	FBXL14	F-box and leucine-rich repeat protein 14. (400 aa)
	FBH1	F-box DNA helicase 1. (999 aa)
	FBXO48	Uncharacterized protein. (137 aa)
	SPSB4	Uncharacterized protein. (273 aa)
	FBXL7	F-box and leucine rich repeat protein 7. (491 aa)
	FBXO9	F-box protein 9. (436 aa)
	SPSB3	SplA/ryanodine receptor domain and SOCS box containing 3. (419 aa)
	FBXO42	F-box protein 42. (748 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	FBXL2	F-box and leucine rich repeat protein 2. (434 aa)
	FBXW8	F-box and WD repeat domain containing 8. (705 aa)
	FBXO7	F-box protein 7. (527 aa)
	AMN1	Antagonist of mitotic exit network 1 homolog. (246 aa)
	FBXO33	F-box domain-containing protein. (296 aa)
	FBXL4	F-box and leucine rich repeat protein 4. (620 aa)
	FBXL3	F-box and leucine rich repeat protein 3. (434 aa)
	FBXO25	F-box protein 25. (381 aa)
	FBXW11	Uncharacterized protein. (563 aa)
	USP47	USP domain-containing protein; Belongs to the peptidase C19 family. (1447 aa)
	FBXO15	F-box protein 15. (481 aa)
	FBXO39	F-box protein 39. (439 aa)
	DAW1	WD_REPEATS_REGION domain-containing protein. (416 aa)
	FBXL18	F-box and leucine rich repeat protein 18. (740 aa)
	LOC115495410	Glycine N-acyltransferase-like protein 3. (282 aa)
	FBXL16	Uncharacterized protein. (513 aa)
	CCNF	Cyclin F; Belongs to the cyclin family. (760 aa)
	FBXW5	F-box and WD repeat domain containing 5. (584 aa)
	H0YVS8_TAEGU	Uncharacterized protein. (282 aa)
	FBXL5	F-box domain-containing protein. (693 aa)
	FBXO2	F-box protein 2. (288 aa)
	TMEM183A	Transmembrane protein 183A. (368 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
	FBXL21P	F-box domain-containing protein. (482 aa)
	FBXO4	F-box protein 4. (317 aa)
	FBXL20	F-box and leucine rich repeat protein 20. (436 aa)
	SKP2	S-phase kinase associated protein 2. (421 aa)
	BTRC	Uncharacterized protein. (667 aa)
	SPSB1	SplA/ryanodine receptor domain and SOCS box containing 1. (273 aa)
	FBXL12	F-box and leucine-rich repeat protein 12. (310 aa)
	FBXO31	F-box protein 31. (568 aa)
	CKS1B	Cyclin-dependent kinase regulatory subunit CKS1. (79 aa)
	CACYBP	Putative calcyclin binding protein. (327 aa)
	FBXO45	F-box protein 45. (272 aa)
	FBXL15	F-box and leucine rich repeat protein 15. (414 aa)
	FBXL17	Uncharacterized protein. (219 aa)
	CUL2	Cullin 2; Belongs to the cullin family. (742 aa)
	CKS2	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMN1	CUL1	ENSTGUP00000011830	ENSTGUP00000001846	Antagonist of mitotic exit network 1 homolog.	Cullin 1; Belongs to the cullin family.	0.527
AMN1	SKP1	ENSTGUP00000011830	ENSTGUP00000001331	Antagonist of mitotic exit network 1 homolog.	S-phase kinase associated protein 1; Belongs to the SKP1 family.	0.750
BTRC	CCNF	ENSTGUP00000017175	ENSTGUP00000003425	Uncharacterized protein.	Cyclin F; Belongs to the cyclin family.	0.569
BTRC	CUL1	ENSTGUP00000017175	ENSTGUP00000001846	Uncharacterized protein.	Cullin 1; Belongs to the cullin family.	0.999
BTRC	FBXO2	ENSTGUP00000017175	ENSTGUP00000002392	Uncharacterized protein.	F-box protein 2.	0.940
BTRC	FBXO4	ENSTGUP00000017175	ENSTGUP00000002329	Uncharacterized protein.	F-box protein 4.	0.913
BTRC	FBXW11	ENSTGUP00000017175	ENSTGUP00000015093	Uncharacterized protein.	Uncharacterized protein.	0.972
BTRC	FBXW8	ENSTGUP00000017175	ENSTGUP00000010678	Uncharacterized protein.	F-box and WD repeat domain containing 8.	0.415
BTRC	SKP1	ENSTGUP00000017175	ENSTGUP00000001331	Uncharacterized protein.	S-phase kinase associated protein 1; Belongs to the SKP1 family.	0.999
BTRC	SKP2	ENSTGUP00000017175	ENSTGUP00000002086	Uncharacterized protein.	S-phase kinase associated protein 2.	0.965
BTRC	USP47	ENSTGUP00000017175	ENSTGUP00000016492	Uncharacterized protein.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.583
CACYBP	SKP1	ENSTGUP00000021901	ENSTGUP00000001331	Putative calcyclin binding protein.	S-phase kinase associated protein 1; Belongs to the SKP1 family.	0.890
CCNF	BTRC	ENSTGUP00000003425	ENSTGUP00000017175	Cyclin F; Belongs to the cyclin family.	Uncharacterized protein.	0.569
CCNF	CKS1B	ENSTGUP00000003425	ENSTGUP00000021766	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinase regulatory subunit CKS1.	0.680
CCNF	CKS2	ENSTGUP00000003425	ENSTGUP00000000454	Cyclin F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.680
CCNF	CUL1	ENSTGUP00000003425	ENSTGUP00000001846	Cyclin F; Belongs to the cyclin family.	Cullin 1; Belongs to the cullin family.	0.904
CCNF	CUL2	ENSTGUP00000003425	ENSTGUP00000000951	Cyclin F; Belongs to the cyclin family.	Cullin 2; Belongs to the cullin family.	0.495
CCNF	FBXW11	ENSTGUP00000003425	ENSTGUP00000015093	Cyclin F; Belongs to the cyclin family.	Uncharacterized protein.	0.469
CCNF	H0Z6S8_TAEGU	ENSTGUP00000003425	ENSTGUP00000026776	Cyclin F; Belongs to the cyclin family.	Gly_acyl_tr_N domain-containing protein.	0.680
CCNF	LOC115495410	ENSTGUP00000003425	ENSTGUP00000006274	Cyclin F; Belongs to the cyclin family.	Glycine N-acyltransferase-like protein 3.	0.680