(83 nodes) Viral life cycle network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	LOC100226241	Ig-like domain-containing protein. (276 aa)
	PDCD6IP	BRO1 domain-containing protein. (878 aa)
	VPS4B	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (441 aa)
	LRSAM1	Leucine rich repeat and sterile alpha motif containing 1. (726 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (797 aa)
	DAG1	Dystroglycan 1. (896 aa)
	TBC1D20	TBC1 domain family member 20. (400 aa)
	H0Z8Z3_TAEGU	Uncharacterized protein; Belongs to the peptidase S9B family. (672 aa)
	ATG16L1	Autophagy related 16 like 1. (608 aa)
	CHMP5	Putative SNF7 domain containing 2 variant 1. (219 aa)
	IST1	IST1 factor associated with ESCRT-III. (365 aa)
	TSG101	Tumor susceptibility 101. (377 aa)
	TPCN1	Two pore segment channel 1. (817 aa)
	LOC100224883	Rab-GAP TBC domain-containing protein. (768 aa)
	SMARCB1	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (386 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	VTA1	Vesicle trafficking 1. (361 aa)
	LOC115493455	a_DG1_N2 domain-containing protein. (579 aa)
	UVRAG	UV radiation resistance associated. (687 aa)
	VPS4A	AAA domain-containing protein. (446 aa)
	H0ZXN7_TAEGU	Ion_trans domain-containing protein. (723 aa)
	SIGLEC1	Uncharacterized protein. (1745 aa)
	ZNF639	Zinc finger protein 639. (475 aa)
	H0ZVV9_TAEGU	Gag_p30 domain-containing protein. (490 aa)
	LOC115491983	Pyruvate carboxylase, mitochondrial. (1176 aa)
	PIKFYVE	Phosphoinositide kinase, FYVE-type zinc finger containing. (2006 aa)
	LOC115492027	Pyruvate carboxylase, mitochondrial-like. (1176 aa)
	LOC100223835	E3 ubiquitin-protein ligase TRIM62. (473 aa)
	ENSTGUP00000021077	Uncharacterized protein LOC116806960. (1013 aa)
	ENSTGUP00000021197	annotation not available (150 aa)
	ENSTGUP00000021200	annotation not available (883 aa)
	VPS37B	VPS37 C-terminal domain-containing protein. (287 aa)
	XPR1	Xenotropic and polytropic retrovirus receptor 1. (692 aa)
	LOC115492748	Ribonuclease kappa. (98 aa)
	ENSTGUP00000023733	annotation not available (883 aa)
	ENSTGUP00000023989	Uncharacterized protein LOC116808964. (812 aa)
	ENSTGUP00000024206	annotation not available (1116 aa)
	TPCN2	Uncharacterized protein. (815 aa)
	ENSTGUP00000024464	annotation not available (493 aa)
	ENSTGUP00000025208	Uncharacterized protein LOC116807394. (316 aa)
	NECTIN4	LOW QUALITY PROTEIN: nectin-4. (537 aa)
	ENSTGUP00000025704	annotation not available (214 aa)
	ENSTGUP00000025830	Protein NYNRIN-like. (1013 aa)
	ENSTGUP00000026198	annotation not available (514 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	LOC115494875	Uncharacterized protein LOC115494875. (874 aa)
	ENSTGUP00000028273	annotation not available (883 aa)
	ENSTGUP00000028952	annotation not available (720 aa)
	ENSTGUP00000029574	annotation not available (129 aa)
	ENSTGUP00000029705	annotation not available (113 aa)
	VAMP8	Vesicle-associated membrane protein 8. (75 aa)
	ENSTGUP00000030040	annotation not available (115 aa)
	CAV2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (163 aa)
	USP6NL	USP6 N-terminal like. (856 aa)
	ENSTGUP00000030207	annotation not available (368 aa)
	LOC115492747	Ribonuclease kappa. (234 aa)
	ENSTGUP00000030955	annotation not available (883 aa)
	H1A5X4_TAEGU	Reverse transcriptase domain-containing protein. (392 aa)
	ENSTGUP00000031967	annotation not available (214 aa)
	ENSTGUP00000032391	annotation not available (425 aa)
	ENSTGUP00000032454	annotation not available (383 aa)
	VPS18	VPS18 core subunit of CORVET and HOPS complexes. (906 aa)
	ENSTGUP00000033233	annotation not available (168 aa)
	ENSTGUP00000033648	annotation not available (565 aa)
	ENSTGUP00000033728	annotation not available (85 aa)
	ENSTGUP00000034094	annotation not available (883 aa)
	LOC100190340	Uncharacterized protein. (261 aa)
	ENSTGUP00000034203	annotation not available (141 aa)
	JPT2	Jupiter microtubule associated homolog 2. (186 aa)
	RAB1A	RAB1A, member RAS oncogene family. (484 aa)
	MVB12B	Multivesicular body subunit 12B. (284 aa)
	ENSTGUP00000034904	annotation not available (115 aa)
	AGTR1	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	SMPD1	Uncharacterized protein. (622 aa)
	ENSTGUP00000035345	annotation not available (367 aa)
	LOC115492065	LOW QUALITY PROTEIN: 4F2 cell-surface antigen heavy chain. (534 aa)
	CLDN1	Claudin 1. (213 aa)
	H1A4P8_TAEGU	Reverse transcriptase domain-containing protein. (883 aa)
	GAS6	Growth arrest specific 6. (704 aa)
	SIVA1	SIVA1 apoptosis inducing factor. (227 aa)
	NECTIN1	Nectin cell adhesion molecule 1. (515 aa)
	LOC115497975	Tripartite motif containing 62. (475 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG16L1	ATG5	ENSTGUP00000007642	ENSTGUP00000032015	Autophagy related 16 like 1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG16L1	RAB1A	ENSTGUP00000007642	ENSTGUP00000034752	Autophagy related 16 like 1.	RAB1A, member RAS oncogene family.	0.505
ATG16L1	UVRAG	ENSTGUP00000007642	ENSTGUP00000013964	Autophagy related 16 like 1.	UV radiation resistance associated.	0.528
ATG5	ATG16L1	ENSTGUP00000032015	ENSTGUP00000007642	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy related 16 like 1.	0.999
ATG5	UVRAG	ENSTGUP00000032015	ENSTGUP00000013964	Autophagy protein 5; Involved in autophagic vesicle formation.	UV radiation resistance associated.	0.673
ATG5	VAMP8	ENSTGUP00000032015	ENSTGUP00000029984	Autophagy protein 5; Involved in autophagic vesicle formation.	Vesicle-associated membrane protein 8.	0.433
CAV1	CAV2	ENSTGUP00000027745	ENSTGUP00000030045	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.997
CAV1	CAV3	ENSTGUP00000027745	ENSTGUP00000010724	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.963
CAV1	DAG1	ENSTGUP00000027745	ENSTGUP00000005324	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dystroglycan 1.	0.460
CAV1	H0Z8Z3_TAEGU	ENSTGUP00000027745	ENSTGUP00000007046	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein; Belongs to the peptidase S9B family.	0.633
CAV1	ITGB3	ENSTGUP00000027745	ENSTGUP00000003271	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Integrin beta; Belongs to the integrin beta chain family.	0.921
CAV1	LOC115493455	ENSTGUP00000027745	ENSTGUP00000012558	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	a_DG1_N2 domain-containing protein.	0.460
CAV2	CAV1	ENSTGUP00000030045	ENSTGUP00000027745	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.997
CAV2	CAV3	ENSTGUP00000030045	ENSTGUP00000010724	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.996
CAV2	ITGB3	ENSTGUP00000030045	ENSTGUP00000003271	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Integrin beta; Belongs to the integrin beta chain family.	0.912
CAV3	CAV1	ENSTGUP00000010724	ENSTGUP00000027745	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.963
CAV3	CAV2	ENSTGUP00000010724	ENSTGUP00000030045	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.996
CAV3	DAG1	ENSTGUP00000010724	ENSTGUP00000005324	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dystroglycan 1.	0.479
CAV3	H0Z8Z3_TAEGU	ENSTGUP00000010724	ENSTGUP00000007046	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein; Belongs to the peptidase S9B family.	0.677
CAV3	ITGB3	ENSTGUP00000010724	ENSTGUP00000003271	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Integrin beta; Belongs to the integrin beta chain family.	0.923