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ENSTGUP00000035290 ENSTGUP00000035290 NDUFA10 NDUFA10 NDUFC2 NDUFC2 ENSTGUP00000036411 ENSTGUP00000036411 LOC100222254 LOC100222254 DGUOK DGUOK ENOX2 ENOX2 SLC25A13 SLC25A13 NDUFB6 NDUFB6 SDHC SDHC UQCRQ UQCRQ NDUFS7 NDUFS7 STEAP4 STEAP4 NDOR1 NDOR1 GTSE1 GTSE1 LOC100221209 LOC100221209 MYBBP1A MYBBP1A AIFM2 AIFM2 COQ9 COQ9 CIAPIN1 CIAPIN1 SURF1 SURF1 NDUFV3 NDUFV3 COX7B COX7B COX7C COX7C H0Z8Y4_TAEGU H0Z8Y4_TAEGU NDUFS8 NDUFS8 B3GNTL1 B3GNTL1 WDR93 WDR93 SDHA SDHA UQCRH UQCRH NDUFS6 NDUFS6 UQCRFS1 UQCRFS1 NDUFV2 NDUFV2 C1orf198 C1orf198 H0ZIL3_TAEGU H0ZIL3_TAEGU UQCR10 UQCR10 NDUFS3 NDUFS3 NDUFAF1 NDUFAF1 FDX1 FDX1 UQCRB UQCRB COX6C COX6C AFG1L AFG1L COX7A2 COX7A2 PINK1 PINK1 PM20D1 PM20D1 LOC101232963 LOC101232963 ENSTGUP00000018717 ENSTGUP00000018717 COX5B COX5B SLC25A12 SLC25A12 ETFA ETFA ENSTGUP00000020069 ENSTGUP00000020069 ETFB ETFB SLC25A22 SLC25A22 POR POR DNAJC15 DNAJC15 SDHAF2 SDHAF2 ETFDH ETFDH NDUFA12 NDUFA12 COA6 COA6 NDUFB9 NDUFB9 NDUFS2 NDUFS2 LOC100221933 LOC100221933 NDUFS1 NDUFS1 NDUFA7 NDUFA7 LOC100218354 LOC100218354 NDUFS4 NDUFS4 ENSTGUP00000030954 ENSTGUP00000030954 ND1 ND1 NDUFA8 NDUFA8 LOC105759871 LOC105759871 FDX2 FDX2 LOC115492000 LOC115492000 LOC100221672 LOC100221672 COX7A2L COX7A2L NDUFB3 NDUFB3 NDUFB8 NDUFB8 PPARGC1A PPARGC1A
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ENSTGUP00000035290annotation not available (234 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (373 aa)
NDUFC2NADH dehydrogenase (ubiquinone) 1 subunit C2. (111 aa)
ENSTGUP00000036411annotation not available (117 aa)
LOC100222254Cytochrome c oxidase subunit 4I1. (464 aa)
DGUOKdNK domain-containing protein. (439 aa)
ENOX2Ecto-NOX disulfide-thiol exchanger 2. (784 aa)
SLC25A13Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (681 aa)
NDUFB6NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6. (254 aa)
SDHCSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial isoform X2. (590 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
NDUFS7NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family. (222 aa)
STEAP4Uncharacterized protein. (495 aa)
NDOR1NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (636 aa)
GTSE1Uncharacterized protein. (659 aa)
LOC100221209Uncharacterized protein. (145 aa)
MYBBP1AMYB binding protein 1a. (1307 aa)
AIFM2Ferroptosis suppressor protein 1; A NAD(P)H-dependent oxidoreductase involved in cellular oxidative stress response. At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubiquinol-10, a lipophilic radical- trapping antioxidant that prevents lipid oxidative damage and consequently ferroptosis. Cooperates with GPX4 to suppress phospholipid peroxidation and ferroptosis. This anti-ferroptotic function is independent of cellular glutathione levels. May play a role in mitochondrial stress signaling. Upon oxidative stress, associates with the lipid peroxidation end produ [...] (373 aa)
COQ9Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (314 aa)
CIAPIN1Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (321 aa)
SURF1SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (320 aa)
NDUFV3Uncharacterized protein. (423 aa)
COX7BPutative cytochrome c oxidase subunit VIIb variant 1. (78 aa)
COX7CPutative cytochrome c oxidase subunit VIIc. (75 aa)
H0Z8Y4_TAEGUUncharacterized protein. (77 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (230 aa)
B3GNTL1UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1. (358 aa)
WDR93Uncharacterized protein. (682 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
UQCRHCytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (146 aa)
NDUFS6NADH:ubiquinone oxidoreductase subunit S6. (128 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (273 aa)
NDUFV2Uncharacterized protein. (244 aa)
C1orf198Chromosome 1 open reading frame 198. (336 aa)
H0ZIL3_TAEGUNADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
UQCR10Uncharacterized protein. (59 aa)
NDUFS3Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family. (478 aa)
NDUFAF1NADH:ubiquinone oxidoreductase complex assembly factor 1. (301 aa)
FDX1Ferredoxin 1. (169 aa)
UQCRBCytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa)
COX6CPutative cytochrome c oxidase subunit VIc. (107 aa)
AFG1LAFG1 like ATPase. (468 aa)
COX7A2Putative cytochrome c oxidase subunit VIIa 2. (83 aa)
PINK1PTEN induced kinase 1. (515 aa)
PM20D1Peptidase M20 domain containing 1. (514 aa)
LOC101232963Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (299 aa)
ENSTGUP00000018717annotation not available (308 aa)
COX5BCytochrome c oxidase subunit 5B, mitochondrial. (126 aa)
SLC25A12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (669 aa)
ETFAElectron transfer flavoprotein subunit alpha. (363 aa)
ENSTGUP00000020069annotation not available (142 aa)
ETFBElectron transfer flavoprotein subunit beta. (254 aa)
SLC25A22Solute carrier family 25 member 22; Belongs to the mitochondrial carrier (TC 2.A.29) family. (400 aa)
PORNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (677 aa)
DNAJC15DnaJ heat shock protein family (Hsp40) member C15. (200 aa)
SDHAF2Uncharacterized protein. (161 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (619 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (185 aa)
COA6Cytochrome c oxidase assembly factor 6. (79 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (174 aa)
NDUFS2NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial. (703 aa)
LOC100221933Uncharacterized protein. (248 aa)
NDUFS1Uncharacterized protein; Belongs to the complex I 75 kDa subunit family. (770 aa)
NDUFA7NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7. (116 aa)
LOC100218354Taeniopygia guttata cytochrome c oxidase subunit 5A, mitochondrial-like (LOC100218354), mRNA. (162 aa)
NDUFS4Putative NADH dehydrogenase Fe-S protein 4. (171 aa)
ENSTGUP00000030954annotation not available (202 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (99 aa)
NDUFA8NADH:ubiquinone oxidoreductase subunit A8. (231 aa)
LOC105759871Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (296 aa)
FDX2Ferredoxin-2, mitochondrial isoform X1. (326 aa)
LOC115492000Tafazzin-like. (272 aa)
LOC1002216722Fe-2S ferredoxin-type domain-containing protein. (183 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (116 aa)
NDUFB3Uncharacterized protein. (96 aa)
NDUFB8Uncharacterized protein. (362 aa)
PPARGC1APPARG coactivator 1 alpha. (807 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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