STRINGSTRING
VPS11 VPS11 CLTA CLTA CLINT1 CLINT1 TLN1 TLN1 DAB2 DAB2 AFTPH AFTPH VAMP3 VAMP3 SH3BP4 SH3BP4 ATP6V0C ATP6V0C AAK1-2 AAK1-2 HAX1 HAX1 ATP6AP1 ATP6AP1 AP3B2 AP3B2 TYRP1 TYRP1 OCRL OCRL FCHO2 FCHO2 SLC18A3 SLC18A3 ADAM10 ADAM10 VPS33A VPS33A PHETA1 PHETA1 ATP6AP2 ATP6AP2 EPN2 EPN2 MALL MALL ATP6V0B ATP6V0B AP1S2 AP1S2 RBP4 RBP4 SCYL2 SCYL2 EPN3 EPN3 AP2A2 AP2A2 CTLA4 CTLA4 ENSTGUP00000010433 ENSTGUP00000010433 AP2M1 AP2M1 TTR TTR INPP5F INPP5F CLVS1 CLVS1 CLRN1 CLRN1 IGF2R IGF2R GOPC GOPC ATP6V1C1 ATP6V1C1 STON2 STON2 MYO6 MYO6 CLBA1 CLBA1 PICALM PICALM CLTC CLTC AP1B1 AP1B1 SYT11 SYT11 SNX9 SNX9 LOC115492856 LOC115492856 LOC115492856-2 LOC115492856-2 TNK2 TNK2 AAK1 AAK1 HIP1R HIP1R SPG21 SPG21 TGOLN2 TGOLN2 RAB8A RAB8A LOC115492748 LOC115492748 LMBRD1 LMBRD1 CLTCL1 CLTCL1 LOC100232199 LOC100232199 ADCY8 ADCY8 AP1G1 AP1G1 CLTB CLTB LOC100219698 LOC100219698 ENSTGUP00000026442 ENSTGUP00000026442 LOC100218431 LOC100218431 ATP6V1H ATP6V1H ENSTGUP00000026806 ENSTGUP00000026806 ENSTGUP00000027350 ENSTGUP00000027350 ENSTGUP00000027548 ENSTGUP00000027548 NECAP1 NECAP1 DBNL DBNL BTBD8 BTBD8 TMED10 TMED10 ASTN1 ASTN1 RAB35 RAB35 ATP6V1D ATP6V1D VPS41 VPS41 AP3B1 AP3B1 VTI1A VTI1A LOC100230284 LOC100230284 ATP6V1F ATP6V1F LOC115492747 LOC115492747 RAB15 RAB15 ATP6V0A1 ATP6V0A1 RASSF9 RASSF9 PHETA2 PHETA2 NRGN NRGN CLVS2 CLVS2 STEAP2 STEAP2 FCHO1 FCHO1 RGS19 RGS19 SYNRG SYNRG DENND1A DENND1A ENSTGUP00000036454 ENSTGUP00000036454 AP2B1 AP2B1 LOC115492738 LOC115492738 SNAP91 SNAP91 AP1S3 AP1S3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (968 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (246 aa)
CLINT1Clathrin interactor 1. (760 aa)
TLN1Talin 1. (2558 aa)
DAB2DAB adaptor protein 2. (716 aa)
AFTPHAftiphilin. (904 aa)
VAMP3V-SNARE coiled-coil homology domain-containing protein. (393 aa)
SH3BP4SH3 domain binding protein 4. (1068 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
AAK1-2BMP2K_C domain-containing protein. (390 aa)
HAX1Uncharacterized protein. (275 aa)
ATP6AP1Uncharacterized protein. (458 aa)
AP3B2AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1102 aa)
TYRP1Tyrosinase related protein 1. (536 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (1295 aa)
FCHO2FCH domain only 2. (975 aa)
SLC18A3Solute carrier family 18 member A3. (528 aa)
ADAM10ADAM metallopeptidase domain 10. (911 aa)
VPS33AUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (601 aa)
PHETA1PH domain containing endocytic trafficking adaptor 1. (255 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (360 aa)
EPN2Epsin 2. (587 aa)
MALLMal, T cell differentiation protein like. (153 aa)
ATP6V0BUncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (194 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (156 aa)
RBP4Retinol binding protein 4; Belongs to the calycin superfamily. Lipocalin family. (226 aa)
SCYL2SCY1 like pseudokinase 2. (932 aa)
EPN3Epsin 3. (639 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (966 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (229 aa)
ENSTGUP00000010433annotation not available (772 aa)
AP2M1MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (437 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (150 aa)
INPP5FUncharacterized protein. (1108 aa)
CLVS1Clavesin 1. (332 aa)
CLRN1Clarin 1. (232 aa)
IGF2RInsulin like growth factor 2 receptor. (2463 aa)
GOPCPDZ domain-containing protein. (631 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
STON2Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (886 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1285 aa)
CLBA1Clathrin binding box of aftiphilin containing 1. (337 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (686 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
AP1B1Adaptor related protein complex 1 subunit beta 1. (991 aa)
SYT11Synaptotagmin 11. (484 aa)
SNX9Sorting nexin. (609 aa)
LOC115492856Adaptor related protein complex 2 subunit sigma 1. (147 aa)
LOC115492856-2AP-2 complex subunit sigma. (185 aa)
TNK2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1208 aa)
AAK1AP2 associated kinase 1. (912 aa)
HIP1RUncharacterized protein. (1047 aa)
SPG21Uncharacterized protein. (310 aa)
TGOLN2Trans-golgi network protein 2. (479 aa)
RAB8ARAB8A, member RAS oncogene family. (263 aa)
LOC115492748Ribonuclease kappa. (98 aa)
LMBRD1LMBR1 domain containing 1. (613 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
LOC100232199DUF1681 domain-containing protein. (377 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1319 aa)
AP1G1AP-1 complex subunit gamma. (820 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (209 aa)
LOC100219698DUF1681 domain-containing protein. (327 aa)
ENSTGUP00000026442annotation not available (342 aa)
LOC100218431SH3 domain GRB2 like endophilin interacting protein 1. (774 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (480 aa)
ENSTGUP00000026806annotation not available (421 aa)
ENSTGUP00000027350annotation not available (165 aa)
ENSTGUP00000027548annotation not available (629 aa)
NECAP1NECAP endocytosis associated 1. (305 aa)
DBNLDrebrin-like protein. (460 aa)
BTBD8BTB domain containing 8. (1785 aa)
TMED10Transmembrane p24 trafficking protein 10. (223 aa)
ASTN1Astrotactin 1. (1293 aa)
RAB35RAB35, member RAS oncogene family. (376 aa)
ATP6V1DATPase H+ transporting V1 subunit D. (246 aa)
VPS41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (894 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1137 aa)
VTI1AVesicle transport through interaction with t-SNAREs 1A. (224 aa)
LOC100230284ENTH domain-containing protein. (683 aa)
ATP6V1FV-type H+-transporting ATPase subunit F. (227 aa)
LOC115492747Ribonuclease kappa. (234 aa)
RAB15Ras-related protein Rab-15 isoform X1. (211 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (861 aa)
RASSF9Ras association domain family member 9. (440 aa)
PHETA2Sesquipedalian-2. (270 aa)
NRGNNeurogranin. (124 aa)
CLVS2Clavesin 2. (327 aa)
STEAP2STEAP2 metalloreductase. (578 aa)
FCHO1F-BAR domain only protein 1 isoform X1. (1020 aa)
RGS19Uncharacterized protein. (392 aa)
SYNRGSynergin gamma. (1446 aa)
DENND1ADENN domain containing 1A. (1107 aa)
ENSTGUP00000036454annotation not available (693 aa)
AP2B1AP complex subunit beta. (953 aa)
LOC115492738AP-1 complex subunit sigma 1/2. (158 aa)
SNAP91Synaptosome associated protein 91. (892 aa)
AP1S3AP-1 complex subunit sigma-3. (196 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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