STRINGSTRING
PKD1 PKD1 NKX2-8 NKX2-8 ZFPM2 ZFPM2 TIMELESS TIMELESS LOC100228958 LOC100228958 IGFBP5 IGFBP5 SAV1 SAV1 ADAMTSL2 ADAMTSL2 ATXN1L ATXN1L LOC100222111 LOC100222111 LOC115492494 LOC115492494 ENSTGUP00000034033 ENSTGUP00000034033 TCF21 TCF21 PGR PGR TGFB2 TGFB2 LOX LOX KDR KDR NKIRAS1 NKIRAS1 EPAS1 EPAS1 DNAAF1 DNAAF1 ENSTGUP00000026997 ENSTGUP00000026997 LOC100225021 LOC100225021 PHF14 PHF14 SEC24B SEC24B FBXW9 FBXW9 FGF2 FGF2 PHEX PHEX ENSTGUP00000023546 ENSTGUP00000023546 CREB1 CREB1 HSPB11 HSPB11 FGF1 FGF1 FLT4 FLT4 SLC7A11 SLC7A11 STK40 STK40 CCBE1 CCBE1 TTC25 TTC25 ERRFI1 ERRFI1 HHIP HHIP SOX9 SOX9 HOXA5 HOXA5 CCDC40 CCDC40 PKDCC PKDCC TGFBR2 TGFBR2 STRA6 STRA6 PITX2 PITX2 NFIB NFIB SRF SRF CTNNB1 CTNNB1 DAG1 DAG1 TMEM38B TMEM38B FBXW7 FBXW7 DLG5 DLG5 FGF7 FGF7 HOPX HOPX NKIRAS2 NKIRAS2 PPP3R1 PPP3R1 H1A448_TAEGU H1A448_TAEGU FGF18 FGF18 WNT11 WNT11 LOC100219136 LOC100219136 H0ZQ02_TAEGU H0ZQ02_TAEGU LOC115493455 LOC115493455 YWHAZ YWHAZ CCN2 CCN2 RDH10 RDH10 FNDC3B FNDC3B LIF LIF TAB1 TAB1 BMPR2 BMPR2 EP300 EP300 CTSH CTSH FGF8 FGF8 AIMP2 AIMP2 SP3 SP3 CTSZ CTSZ SMPD3 SMPD3 RC3H2 RC3H2 MYOCD MYOCD RXFP1 RXFP1 ESRP2 ESRP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKD1Polycystin 1, transient receptor potential channel interacting. (4230 aa)
NKX2-8Homeobox protein Nkx-2.8. (236 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1179 aa)
TIMELESSProtein timeless homolog isoform X1. (1338 aa)
LOC100228958WD_REPEATS_REGION domain-containing protein. (783 aa)
IGFBP5Insulin like growth factor binding protein 5. (269 aa)
SAV1Salvador family WW domain containing protein 1. (379 aa)
ADAMTSL2ADAMTS like 2. (957 aa)
ATXN1LAtaxin-1-like isoform X1. (688 aa)
LOC100222111Corticosteroid 11-beta-dehydrogenase isozyme 1-like. (298 aa)
LOC115492494Corticosteroid 11-beta-dehydrogenase isozyme 1-like. (298 aa)
ENSTGUP00000034033annotation not available (1338 aa)
TCF21Transcription factor 21. (179 aa)
PGRProgesterone receptor. (776 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (433 aa)
LOXLysyl oxidase. (453 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (162 aa)
EPAS1Endothelial PAS domain protein 1. (866 aa)
DNAAF1Dynein assembly factor 1, axonemal. (646 aa)
ENSTGUP00000026997annotation not available (687 aa)
LOC100225021Hydroxysteroid 11-beta dehydrogenase 1. (293 aa)
PHF14PHD finger protein 14. (939 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1232 aa)
FBXW9Uncharacterized protein. (526 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (153 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (751 aa)
ENSTGUP00000023546annotation not available (228 aa)
CREB1cAMP responsive element binding protein 1. (324 aa)
HSPB11Heat shock protein family B (small) member 11. (141 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1379 aa)
SLC7A11Solute carrier family 7 member 11. (503 aa)
STK40Protein kinase domain-containing protein. (431 aa)
CCBE1Collagen and calcium binding EGF domains 1. (394 aa)
TTC25Tetratricopeptide repeat domain 25. (594 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (463 aa)
HHIPHedgehog interacting protein. (723 aa)
SOX9SRY-box transcription factor 9. (474 aa)
HOXA5Homeobox A5. (270 aa)
CCDC40Coiled-coil domain containing 40. (951 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (499 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (568 aa)
STRA6Uncharacterized protein. (560 aa)
PITX2Homeobox protein. (360 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (569 aa)
SRFSerum response factor. (485 aa)
CTNNB1Catenin beta 1. (781 aa)
DAG1Dystroglycan 1. (896 aa)
TMEM38BTransmembrane protein 38B. (343 aa)
FBXW7F-box and WD repeat domain containing 7. (745 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (2045 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
HOPXUncharacterized protein. (267 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (191 aa)
PPP3R1Uncharacterized protein. (167 aa)
H1A448_TAEGUPLAC domain-containing protein. (973 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
LOC100219136PIP49_C domain-containing protein. (518 aa)
H0ZQ02_TAEGUUncharacterized protein. (480 aa)
LOC115493455a_DG1_N2 domain-containing protein. (579 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
CCN2Cellular communication network factor 2. (347 aa)
RDH10Uncharacterized protein. (343 aa)
FNDC3BFibronectin type III domain containing 3B. (1139 aa)
LIFLIF interleukin 6 family cytokine. (211 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1036 aa)
EP300E1A binding protein p300. (2445 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (367 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
AIMP2Aminoacyl tRNA synthetase complex interacting multifunctional protein 2. (314 aa)
SP3Sp3 transcription factor. (773 aa)
CTSZPept_C1 domain-containing protein; Belongs to the peptidase C1 family. (300 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (660 aa)
RC3H2Ring finger and CCCH-type domains 2. (1191 aa)
MYOCDMyocardin. (875 aa)
RXFP1Relaxin family peptide receptor 1. (766 aa)
ESRP2Epithelial splicing regulatory protein 2. (727 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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