(22 nodes) cAMP binding network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRKAR2A	Uncharacterized protein. (399 aa)
	POPDC2	Popeye domain containing 2. (370 aa)
	ENSTGUP00000033742	annotation not available (1045 aa)
	HCN4-2	Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1216 aa)
	PDE10A	Phosphodiesterase. (1058 aa)
	POPDC3	Popeye domain-containing protein 3. (307 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2. (1804 aa)
	LOC115491504	Cyclic nucleotide-binding domain-containing protein. (932 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (1026 aa)
	HCN3	Cyclic nucleotide-binding domain-containing protein. (999 aa)
	PDE2A	Phosphodiesterase. (949 aa)
	PRKAR2B	Protein kinase cAMP-dependent type II regulatory subunit beta. (591 aa)
	CNGA4	Cyclic nucleotide-gated cation channel alpha-4. (686 aa)
	BVES	Blood vessel epicardial substance. (359 aa)
	CNGA3	Cyclic nucleotide gated channel subunit alpha 3. (672 aa)
	PRKAR1B	Protein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
	CNGA1	Cyclic nucleotide gated channel subunit alpha 1. (645 aa)
	CNGA2	Cyclic nucleotide gated channel subunit alpha 2. (666 aa)
	HCN4	Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (659 aa)
	PRKAR1A	Protein kinase cAMP-dependent type I regulatory subunit alpha. (382 aa)
	HCN1	Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (597 aa)
	HCN2	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (919 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNGA2	CNGA3	ENSTGUP00000006605	ENSTGUP00000010601	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide gated channel subunit alpha 3.	0.401
CNGA2	CNGA4	ENSTGUP00000006605	ENSTGUP00000022355	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide-gated cation channel alpha-4.	0.880
CNGA3	CNGA2	ENSTGUP00000010601	ENSTGUP00000006605	Cyclic nucleotide gated channel subunit alpha 3.	Cyclic nucleotide gated channel subunit alpha 2.	0.401
CNGA4	CNGA2	ENSTGUP00000022355	ENSTGUP00000006605	Cyclic nucleotide-gated cation channel alpha-4.	Cyclic nucleotide gated channel subunit alpha 2.	0.880
ENSTGUP00000033742	RAPGEF4	ENSTGUP00000033742	ENSTGUP00000028025	annotation not available	Rap guanine nucleotide exchange factor 4.	0.493
LOC115491504	RAPGEF4	ENSTGUP00000028484	ENSTGUP00000028025	Cyclic nucleotide-binding domain-containing protein.	Rap guanine nucleotide exchange factor 4.	0.945
PRKAR1A	PRKAR1B	ENSTGUP00000004221	ENSTGUP00000008775	Protein kinase cAMP-dependent type I regulatory subunit alpha.	Protein kinase cAMP-dependent type I regulatory subunit beta.	0.422
PRKAR1A	PRKAR2A	ENSTGUP00000004221	ENSTGUP00000009429	Protein kinase cAMP-dependent type I regulatory subunit alpha.	Uncharacterized protein.	0.447
PRKAR1B	PRKAR1A	ENSTGUP00000008775	ENSTGUP00000004221	Protein kinase cAMP-dependent type I regulatory subunit beta.	Protein kinase cAMP-dependent type I regulatory subunit alpha.	0.422
PRKAR1B	PRKAR2A	ENSTGUP00000008775	ENSTGUP00000009429	Protein kinase cAMP-dependent type I regulatory subunit beta.	Uncharacterized protein.	0.449
PRKAR2A	PRKAR1A	ENSTGUP00000009429	ENSTGUP00000004221	Uncharacterized protein.	Protein kinase cAMP-dependent type I regulatory subunit alpha.	0.447
PRKAR2A	PRKAR1B	ENSTGUP00000009429	ENSTGUP00000008775	Uncharacterized protein.	Protein kinase cAMP-dependent type I regulatory subunit beta.	0.449
RAPGEF4	ENSTGUP00000033742	ENSTGUP00000028025	ENSTGUP00000033742	Rap guanine nucleotide exchange factor 4.	annotation not available	0.493
RAPGEF4	LOC115491504	ENSTGUP00000028025	ENSTGUP00000028484	Rap guanine nucleotide exchange factor 4.	Cyclic nucleotide-binding domain-containing protein.	0.945