(35 nodes) Regulation of B cell proliferation network (Taeniopygia guttata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CD38	CD38 molecule. (506 aa)
	IL10	Interleukin 10. (165 aa)
	RC3H1	Uncharacterized protein. (1124 aa)
	ATAD5	ATPase family AAA domain containing 5. (1827 aa)
	SASH3	Uncharacterized protein. (568 aa)
	MSH6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1262 aa)
	CD40	CD40 molecule. (280 aa)
	TNFRSF13B	TNF receptor superfamily member 13B. (258 aa)
	CLCF1	Cardiotrophin like cytokine factor 1. (257 aa)
	PMS2	PMS1 homolog 2, mismatch repair system component. (870 aa)
	BCL6	BCL6 transcription repressor. (729 aa)
	CTLA4	Cytotoxic T-lymphocyte associated protein 4. (229 aa)
	TNFRSF13C	Uncharacterized protein. (211 aa)
	TNFSF13B	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (288 aa)
	GPR183	G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (381 aa)
	IL7	Uncharacterized protein. (179 aa)
	ATM	Non-specific serine/threonine protein kinase. (2226 aa)
	BLK	Tyrosine-protein kinase. (499 aa)
	CD74	Uncharacterized protein. (289 aa)
	TIRAP	TIR domain containing adaptor protein. (410 aa)
	INPP5D	Inositol polyphosphate-5-phosphatase D. (1214 aa)
	MZB1	Marginal zone B- and B1-cell-specific protein isoform X1. (122 aa)
	LYN	Tyrosine-protein kinase. (605 aa)
	LOC100223529	RHD domain-containing protein. (925 aa)
	TNFRSF21	TNF receptor superfamily member 21. (658 aa)
	LOC101232862	RHD_dimer domain-containing protein. (700 aa)
	BST1	Bone marrow stromal cell antigen 1. (316 aa)
	TFRC	Transferrin receptor. (776 aa)
	PTPRC	Uncharacterized protein. (1194 aa)
	PAWR	Uncharacterized protein. (325 aa)
	CARD11	Caspase recruitment domain family member 11. (1167 aa)
	PELI1	Uncharacterized protein. (460 aa)
	IKZF3	IKAROS family zinc finger 3. (561 aa)
	IL21	Interleukin; Belongs to the IL-15/IL-21 family. (194 aa)
	TNFRSF4	Uncharacterized protein. (319 aa)

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	ATM	ENSTGUP00000005092	ENSTGUP00000013001	ATPase family AAA domain containing 5.	Non-specific serine/threonine protein kinase.	0.513
ATAD5	MSH6	ENSTGUP00000005092	ENSTGUP00000005725	ATPase family AAA domain containing 5.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.485
ATM	ATAD5	ENSTGUP00000013001	ENSTGUP00000005092	Non-specific serine/threonine protein kinase.	ATPase family AAA domain containing 5.	0.513
ATM	MSH6	ENSTGUP00000013001	ENSTGUP00000005725	Non-specific serine/threonine protein kinase.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.843
ATM	PMS2	ENSTGUP00000013001	ENSTGUP00000009059	Non-specific serine/threonine protein kinase.	PMS1 homolog 2, mismatch repair system component.	0.767
BCL6	CD40	ENSTGUP00000009713	ENSTGUP00000005997	BCL6 transcription repressor.	CD40 molecule.	0.470
BLK	PTPRC	ENSTGUP00000013694	ENSTGUP00000027581	Tyrosine-protein kinase.	Uncharacterized protein.	0.423
BST1	CD40	ENSTGUP00000027274	ENSTGUP00000005997	Bone marrow stromal cell antigen 1.	CD40 molecule.	0.415
CARD11	CTLA4	ENSTGUP00000032603	ENSTGUP00000010068	Caspase recruitment domain family member 11.	Cytotoxic T-lymphocyte associated protein 4.	0.502
CD38	CD40	ENSTGUP00000036637	ENSTGUP00000005997	CD38 molecule.	CD40 molecule.	0.465
CD38	CTLA4	ENSTGUP00000036637	ENSTGUP00000010068	CD38 molecule.	Cytotoxic T-lymphocyte associated protein 4.	0.401
CD38	IL21	ENSTGUP00000036637	ENSTGUP00000035114	CD38 molecule.	Interleukin; Belongs to the IL-15/IL-21 family.	0.503
CD38	PTPRC	ENSTGUP00000036637	ENSTGUP00000027581	CD38 molecule.	Uncharacterized protein.	0.505
CD40	BCL6	ENSTGUP00000005997	ENSTGUP00000009713	CD40 molecule.	BCL6 transcription repressor.	0.470
CD40	BST1	ENSTGUP00000005997	ENSTGUP00000027274	CD40 molecule.	Bone marrow stromal cell antigen 1.	0.415
CD40	CD38	ENSTGUP00000005997	ENSTGUP00000036637	CD40 molecule.	CD38 molecule.	0.465
CD40	CTLA4	ENSTGUP00000005997	ENSTGUP00000010068	CD40 molecule.	Cytotoxic T-lymphocyte associated protein 4.	0.684
CD40	IL10	ENSTGUP00000005997	ENSTGUP00000001118	CD40 molecule.	Interleukin 10.	0.568
CD40	PTPRC	ENSTGUP00000005997	ENSTGUP00000027581	CD40 molecule.	Uncharacterized protein.	0.421
CD40	TNFRSF13C	ENSTGUP00000005997	ENSTGUP00000010074	CD40 molecule.	Uncharacterized protein.	0.446