STRINGSTRING
CACTIN CACTIN WNT3 WNT3 DRD2 DRD2 NLRX1 NLRX1 GRIN3A GRIN3A PTPRS PTPRS SMPDL3B SMPDL3B IL10 IL10 CXCL8 CXCL8 CLASP2 CLASP2 ILRUN ILRUN GATA3 GATA3 PTGER4 PTGER4 TNFRSF1B TNFRSF1B SEMA3A SEMA3A SEMA3E SEMA3E HGF HGF SUSD4 SUSD4 FGL2 FGL2 H0YX69_TAEGU H0YX69_TAEGU MMRN1 MMRN1 TRAF3IP1 TRAF3IP1 C1QTNF1 C1QTNF1 SAMHD1 SAMHD1 NR1D2 NR1D2 SOCS3 SOCS3 ITCH ITCH SEMA4A SEMA4A NLRC3 NLRC3 MKRN2 MKRN2 PPARG PPARG ADAR ADAR APOH APOH WFDC1 WFDC1 NELL1 NELL1 IL20RB IL20RB MMP28 MMP28 PLA2G10 PLA2G10 LOC100224101 LOC100224101 FGG FGG LOC100226594 LOC100226594 NELL2 NELL2 CST7 CST7 MKKS MKKS SEMA3G SEMA3G SH2B3 SH2B3 TKFC TKFC SEMA3B SEMA3B BBS2 BBS2 C5 C5 TRAFD1 TRAFD1 H0Z8Z3_TAEGU H0Z8Z3_TAEGU CYP19A1 CYP19A1 MYOZ1 MYOZ1 SEMA6D SEMA6D CNOT7 CNOT7 MVK MVK OTULIN OTULIN OTULINL OTULINL PROC PROC CYLD CYLD METRNL METRNL GPR17 GPR17 SEMA5A SEMA5A SEC14L1 SEC14L1 UFD1 UFD1 NUCB2 NUCB2 VPS35 VPS35 SELENOS SELENOS NR1H4 NR1H4 H0ZG36_TAEGU H0ZG36_TAEGU SLIT2 SLIT2 SLIT1 SLIT1 OTOP1 OTOP1 LYAR LYAR SEMA4B SEMA4B RIOK3 RIOK3 HRG HRG F2 F2 MDK MDK GHSR GHSR IL22RA2 IL22RA2 TNFAIP3 TNFAIP3 INPP5F INPP5F YTHDF3 YTHDF3 LOC100231371 LOC100231371 ARG2 ARG2 THBS1 THBS1 PPARA PPARA CD9 CD9 TNFAIP6 TNFAIP6 TTLL12 TTLL12 SPX SPX RB1 RB1 CPB2 CPB2 CCN3 CCN3 ACOD1 ACOD1 RIN3 RIN3 H0ZR88_TAEGU H0ZR88_TAEGU ANGPT2 ANGPT2 LPCAT3 LPCAT3 TNFRSF1A TNFRSF1A DRD3 DRD3 H0ZT62_TAEGU H0ZT62_TAEGU PHLDB2 PHLDB2 CD96 CD96 GRN GRN FNDC4 FNDC4 H0ZZY6_TAEGU H0ZZY6_TAEGU CLDN19 CLDN19 YTHDF2 YTHDF2 PSMB4 PSMB4 SYT11 SYT11 ASH1L ASH1L LRIG2 LRIG2 SEMA6A SEMA6A GPR18 GPR18 ABCC8 ABCC8 AOAH AOAH ENSTGUP00000018634 ENSTGUP00000018634 CZH5orf30 CZH5orf30 C1QTNF6 C1QTNF6 LOC100228042-2 LOC100228042-2 PDGFB PDGFB ADIPOQ ADIPOQ C1QBP C1QBP SEMA3C SEMA3C GFER GFER ATG12 ATG12 CD200 CD200 ENSTGUP00000022263 ENSTGUP00000022263 SOCS5 SOCS5 APOA1 APOA1 PPARD PPARD CD34 CD34 SERPING1 SERPING1 TFPI TFPI PTPRD PTPRD SEMA4G SEMA4G PTPN2 PTPN2 PBK PBK LOC115492161 LOC115492161 RABGEF1 RABGEF1 DHX58 DHX58 ADTRP ADTRP SEMA4D SEMA4D NMI NMI CLASP1 CLASP1 TSPAN6 TSPAN6 GPATCH3 GPATCH3 FFAR4 FFAR4 KREMEN1 KREMEN1 CASK CASK LOC100228042 LOC100228042 METTL3 METTL3 LOC115497877 LOC115497877 NLRP3 NLRP3 RNF26 RNF26 LOC100219522 LOC100219522 SEMA3D SEMA3D NRXN2 NRXN2 LOC115495221 LOC115495221 LEP LEP SEMA7A SEMA7A TNFRSF8 TNFRSF8 NT5E NT5E NR1D1 NR1D1 LOC100222319 LOC100222319 SEMA3F SEMA3F PLA2G2A PLA2G2A LOC100217684 LOC100217684 ATG5 ATG5 CARTPT CARTPT SHARPIN SHARPIN RYK RYK RTN4RL1 RTN4RL1 SEMA4C SEMA4C MFHAS1 MFHAS1 DUSP10 DUSP10 RGMA RGMA LOC100217684-2 LOC100217684-2 CX3CL1 CX3CL1 NENF NENF AJAP1 AJAP1 LOC100226999 LOC100226999 ENSTGUP00000034621 ENSTGUP00000034621 CXCL8-2 CXCL8-2 SEMA6C SEMA6C PROS1 PROS1 MUL1 MUL1 SEMA6B SEMA6B LOC115494026 LOC115494026 LRFN5 LRFN5 LOC115492161-2 LOC115492161-2 BBS4 BBS4 NRXN1 NRXN1 TAFA3 TAFA3 LOC100219655 LOC100219655 UCN UCN CXCL8-3 CXCL8-3 UBASH3B UBASH3B SEMA5B SEMA5B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CACTINCactin, spliceosome C complex subunit. (771 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (473 aa)
NLRX1NLR family member X1. (1059 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1111 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1899 aa)
SMPDL3BSphingomyelin phosphodiesterase acid like 3B. (639 aa)
IL10Interleukin 10. (165 aa)
CXCL8Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (107 aa)
CLASP2Cytoplasmic linker associated protein 2. (1408 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (291 aa)
GATA3GATA binding protein 3. (443 aa)
PTGER4Prostaglandin E receptor 4. (460 aa)
TNFRSF1BUncharacterized protein. (457 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (820 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (726 aa)
SUSD4Sushi domain containing 4. (483 aa)
FGL2Fibrinogen like 2. (481 aa)
H0YX69_TAEGUIg-like domain-containing protein. (331 aa)
MMRN1Multimerin 1. (1194 aa)
TRAF3IP1TRAF3-interacting protein 1 isoform X1. (659 aa)
C1QTNF1Uncharacterized protein. (276 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (605 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2. (573 aa)
SOCS3Suppressor of cytokine signaling 3. (209 aa)
ITCHE3 ubiquitin-protein ligase. (874 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (779 aa)
NLRC3NLR family CARD domain containing 3. (1006 aa)
MKRN2Makorin ring finger protein 2. (826 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (473 aa)
ADARAdenosine deaminase RNA specific. (1169 aa)
APOHUncharacterized protein. (350 aa)
WFDC1WAP four-disulfide core domain 1. (410 aa)
NELL1Neural EGFL like 1. (808 aa)
IL20RBInterleukin 20 receptor subunit beta. (307 aa)
MMP28Matrix metallopeptidase 28. (463 aa)
PLA2G10Phospholipase A(2). (158 aa)
LOC100224101Uncharacterized protein; Belongs to the semaphorin family. (765 aa)
FGGFibrinogen gamma chain. (433 aa)
LOC100226594Uncharacterized protein. (461 aa)
NELL2Neural EGFL like 2. (816 aa)
CST7Cystatin F. (265 aa)
MKKSMcKusick-Kaufman syndrome. (583 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (771 aa)
SH2B3SH2B adaptor protein 3. (579 aa)
TKFCTriokinase and FMN cyclase. (669 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (755 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
C5Uncharacterized protein. (1678 aa)
TRAFD1TRAF-type domain-containing protein. (203 aa)
H0Z8Z3_TAEGUUncharacterized protein; Belongs to the peptidase S9B family. (672 aa)
CYP19A1Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (509 aa)
MYOZ1Myozenin 1. (294 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1088 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (297 aa)
OTULINLOTU deubiquitinase with linear linkage specificity like. (369 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa. (431 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (953 aa)
METRNLMeteorin like, glial cell differentiation regulator. (292 aa)
GPR17G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family. (343 aa)
SEMA5ASemaphorin 5A. (1076 aa)
SEC14L1SEC14 like lipid binding 1. (715 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (307 aa)
NUCB2Uncharacterized protein. (468 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (816 aa)
SELENOSSelenoprotein S. (188 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (473 aa)
H0ZG36_TAEGUUncharacterized protein. (558 aa)
SLIT2Slit guidance ligand 2. (1541 aa)
SLIT1Slit guidance ligand 1. (1538 aa)
OTOP1Otopetrin 1. (576 aa)
LYARLy1 antibody reactive. (363 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (830 aa)
RIOK3Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (513 aa)
HRGUncharacterized protein. (626 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (608 aa)
MDKMidkine. (139 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (352 aa)
IL22RA2Interleukin 22 receptor subunit alpha 2. (239 aa)
TNFAIP3TNF alpha induced protein 3. (804 aa)
INPP5FUncharacterized protein. (1108 aa)
YTHDF3YTH N6-methyladenosine RNA binding protein 3. (691 aa)
LOC100231371Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (802 aa)
ARG2Arginase. (356 aa)
THBS1Uncharacterized protein. (1173 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
CD9Tetraspanin. (302 aa)
TNFAIP6TNF alpha induced protein 6. (296 aa)
TTLL12Tubulin tyrosine ligase like 12. (627 aa)
SPXSpexin hormone. (134 aa)
RB1RB transcriptional corepressor 1. (931 aa)
CPB2Carboxypeptidase B2. (424 aa)
CCN3Cellular communication network factor 3. (377 aa)
ACOD1Uncharacterized protein. (474 aa)
RIN3Ras and Rab interactor 3. (968 aa)
H0ZR88_TAEGUUncharacterized protein. (743 aa)
ANGPT2Angiopoietin 2. (494 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (469 aa)
TNFRSF1AUncharacterized protein. (429 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (493 aa)
H0ZT62_TAEGUPhospholipase A(2). (255 aa)
PHLDB2PH domain-containing protein. (981 aa)
CD96Uncharacterized protein. (550 aa)
GRNGranulin precursor. (611 aa)
FNDC4Fibronectin type III domain containing 4. (310 aa)
H0ZZY6_TAEGUIg-like domain-containing protein. (191 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (573 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (271 aa)
SYT11Synaptotagmin 11. (484 aa)
ASH1LASH1 like histone lysine methyltransferase. (2963 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1068 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1044 aa)
GPR18G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (321 aa)
ABCC8ATP binding cassette subfamily C member 8. (1620 aa)
AOAHAcyloxyacyl hydrolase. (582 aa)
ENSTGUP00000018634annotation not available (359 aa)
CZH5orf30Chromosome 5 open reading frame 30. (207 aa)
C1QTNF6C1q and TNF related 6. (319 aa)
LOC100228042-2PAD domain-containing protein. (680 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (278 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (245 aa)
C1QBPComplement C1q binding protein. (287 aa)
SEMA3CUncharacterized protein; Belongs to the semaphorin family. (751 aa)
GFERSulfhydryl oxidase. (215 aa)
ATG12Autophagy related 12. (249 aa)
CD200CD200 molecule. (284 aa)
ENSTGUP00000022263annotation not available (183 aa)
SOCS5Suppressor of cytokine signaling 5. (535 aa)
APOA1Uncharacterized protein. (264 aa)
PPARDUncharacterized protein. (449 aa)
CD34Uncharacterized protein. (372 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (656 aa)
TFPITissue factor pathway inhibitor isoform X7. (429 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1919 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (844 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (420 aa)
PBKLymphokine-activated killer T-cell-originated protein kinase. (687 aa)
LOC115492161Barrier-to-autointegration factor. (90 aa)
RABGEF1Uncharacterized protein. (538 aa)
DHX58DExH-box helicase 58. (776 aa)
ADTRPAndrogen dependent TFPI regulating protein. (267 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (1032 aa)
NMIUncharacterized protein. (295 aa)
CLASP1Uncharacterized protein. (1555 aa)
TSPAN6Tetraspanin 6; Belongs to the tetraspanin (TM4SF) family. (371 aa)
GPATCH3G-patch domain containing 3. (562 aa)
FFAR4Free fatty acid receptor 4. (354 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (390 aa)
CASKUncharacterized protein; Belongs to the MAGUK family. (921 aa)
LOC100228042Uncharacterized protein. (678 aa)
METTL3Methyltransferase like 3. (449 aa)
LOC115497877OX-2 membrane glycoprotein-like. (407 aa)
NLRP3NACHT domain-containing protein. (901 aa)
RNF26RING-type domain-containing protein. (460 aa)
LOC100219522NAD-dependent protein deacetylase sirtuin-2-like. (455 aa)
SEMA3DUncharacterized protein; Belongs to the semaphorin family. (761 aa)
NRXN2Neurexin 2. (1546 aa)
LOC115495221Uncharacterized protein. (420 aa)
LEPTaeniopygia guttata leptin (LEP), mRNA. (168 aa)
SEMA7ASema domain-containing protein. (633 aa)
TNFRSF8Uncharacterized protein. (480 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (578 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (553 aa)
LOC100222319Uncharacterized protein. (710 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (729 aa)
PLA2G2APhospholipase A2 group IIA. (132 aa)
LOC100217684Reticulon 4 receptor. (482 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
CARTPTCART prepropeptide. (137 aa)
SHARPINSHANK associated RH domain interactor. (380 aa)
RYKReceptor like tyrosine kinase. (696 aa)
RTN4RL1Reticulon-4 receptor-like 1. (455 aa)
SEMA4CSema domain-containing protein; Belongs to the semaphorin family. (907 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1104 aa)
DUSP10Dual specificity phosphatase 10. (481 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (445 aa)
LOC100217684-2Reticulon-4 receptor. (482 aa)
CX3CL1Uncharacterized protein. (429 aa)
NENFNeudesin neurotrophic factor; Belongs to the cytochrome b5 family. (177 aa)
AJAP1AJAP1_PANP_C domain-containing protein. (364 aa)
LOC100226999Semaphorin-4C. (860 aa)
ENSTGUP00000034621annotation not available (86 aa)
CXCL8-2Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (184 aa)
SEMA6CSemaphorin 6C. (963 aa)
PROS1Uncharacterized protein. (659 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (405 aa)
SEMA6BSemaphorin-6B. (906 aa)
LOC115494026Ubiquitin carboxyl-terminal hydrolase CYLD isoform X1. (786 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (772 aa)
LOC115492161-2Barrier-to-autointegration factor. (90 aa)
BBS4Bardet-Biedl syndrome 4. (565 aa)
NRXN1Neurexin 1. (1499 aa)
TAFA3TAFA chemokine like family member 3. (194 aa)
LOC100219655semaphorin-7A. (1169 aa)
UCNUrocortin. (99 aa)
CXCL8-3Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (102 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (653 aa)
SEMA5BSemaphorin 5B. (1092 aa)
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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